利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

18 条记录 (耗时 0.021 秒)

    Shafts with pressure relief in cryotherapeutic catheters and associated devices, systems, and methods
    1.
    发明授权
    Shafts with pressure relief in cryotherapeutic catheters and associated devices, systems, and methods 有权
    在冷冻治疗导管和相关装置，系统和方法中具有压力释放的轴

    公开(公告)号：US09241752B2

    公开(公告)日：2016-01-26

    申请号：US13458120

    申请日：2012-04-27

    申请人： Stephen Nash ,  Grace Kelly

    发明人： Stephen Nash ,  Grace Kelly

    IPC分类号： A61B18/02 ,  A61M25/10 ,  A61B18/00 ,  A61B19/00

    CPC分类号： A61B18/02 ,  A61B90/03 ,  A61B2018/00005 ,  A61B2018/00023 ,  A61B2018/00166 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268 ,  A61B2090/032 ,  A61B2090/037 ,  A61M25/1006 ,  A61M25/10184 ,  A61M25/1025 ,  A61M2025/1061 ,  F04C2270/041

    摘要： Cryotherapeutic systems with features that can facilitate pressure relief in the event of exhaust-passage blockage and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment can include an elongated shaft having a distal portion and a pressure-relief portion proximal to the distal portion. The cryotherapeutic system can further include a supply lumen, an exhaust passage, and a balloon configured to receive refrigerant from the supply lumen and to exhaust refrigerant to the exhaust passage. The pressure-relief portion can be configured to release refrigerant from the exhaust passage when a pressure of refrigerant in the exhaust passage exceeds a threshold pressure less than a pressure rating of the balloon. The pressure-relief portion, for example, can include a rupture element configured to rupture at about the threshold pressure.

    摘要翻译： 本文公开了具有能够促进在排气通道堵塞的情况下的压力释放以及相关的装置，系统和方法的特征的冷冻治疗系统。 根据特定实施例构造的冷冻治疗系统可以包括细长轴，其具有远侧部分和靠近远端部分的压力释放部分。 冷冻治疗系统还可以包括供应管腔，排气通道和被配置为从供应管腔接纳制冷剂并将制冷剂排出到排气通道的气囊。 当排气通道中的制冷剂的压力超过小于气囊的额定压力的阈值压力时，减压部分可被构造成从排气通道释放制冷剂。 例如，减压部分可以包括构造成在约阈值压力下破裂的断裂元件。

    Catheter Having a Detachable Tip
    3.
    发明申请
    Catheter Having a Detachable Tip 失效
    导管有一个可拆卸的提示

    公开(公告)号：US20090264858A1

    公开(公告)日：2009-10-22

    申请号：US12107527

    申请日：2008-04-22

    申请人： Stephen Nash ,  Patricia O'Beirne ,  David Johnson ,  Stephen Gormley ,  Grace Kelly

    发明人： Stephen Nash ,  Patricia O'Beirne ,  David Johnson ,  Stephen Gormley ,  Grace Kelly

    IPC分类号： A61M31/00 ,  A61M25/00

    CPC分类号： A61M25/0069 ,  A61M2025/0057 ,  A61M2025/1093

    摘要： A catheter is disclosed that has a detachable tip for delivery of a therapeutic substance to a chronic total occlusion (CTO) within a body vessel. The tip is made from a biodegradable material and includes an active agent dispersed therethrough. The detachable tip pierces into the calcified lesion, detaches from the catheter, and remains embedded within the lesion as the tip degrades, thereby releasing the active agent. The active agent is a therapeutic substance effective to treat of a CTO. The active agent may be a drug, an enzyme, bacteria, or a parasite that degrades or softens the calcified lesion.

    摘要翻译： 公开了一种导管，其具有用于将治疗物质递送至体内容器内的慢性完全闭塞（CTO）的可拆卸末端。 尖端由可生物降解的材料制成并且包括分散在其中的活性剂。 可拆卸的尖端刺入钙化的病变，从导管分离，并且随着尖端降解而保持嵌入损伤内，从而释放活性剂。 活性剂是有效治疗CTO的治疗物质。 活性剂可以是降解或软化钙化病变的药物，酶，细菌或寄生虫。

    Acoustical warning system
    4.
    发明授权
    Acoustical warning system 有权
    声学预警系统

    公开(公告)号：US08998148B2

    公开(公告)日：2015-04-07

    申请号：US13507214

    申请日：2012-06-13

    申请人： Basant K. Parida ,  Abdullatif K. Zaouk ,  Jason Ross ,  Grant Stephen Nash

    发明人： Basant K. Parida ,  Abdullatif K. Zaouk ,  Jason Ross ,  Grant Stephen Nash

    IPC分类号： B61L23/00 ,  B61L25/02 ,  B61L29/00

    CPC分类号： B61L23/00

    摘要： A locomotive warning system includes an acoustical warning subsystem configured to emit variably directed sound. A controller subsystem is responsive to an initiation command and is configured to trigger the acoustical warning subsystem to begin a sounding sequence when the initiation command is received at a first directivity angle and to continue the sound blast sequence at increasing directivity angles for a pre-establish time and/or distance traveled.

    摘要翻译： 机车警告系统包括配置成发射可变导向声音的声学警告子系统。 控制器子系统响应于启动命令，并且被配置为当以第一方向角度接收到启动命令时触发声音警告子系统开始探测序列，并且以增加的方向角度继续声音喷射序列，用于预先建立 时间和/或距离。

    Catheter having a detachable tip
    7.
    发明授权
    Catheter having a detachable tip 失效
    导管具有可拆卸的尖端

    公开(公告)号：US08016799B2

    公开(公告)日：2011-09-13

    申请号：US12107527

    申请日：2008-04-22

    申请人： Stephen Nash ,  Patricia O'Beirne ,  David Johnson ,  Stephen Gormley ,  Grace Kelly

    发明人： Stephen Nash ,  Patricia O'Beirne ,  David Johnson ,  Stephen Gormley ,  Grace Kelly

    IPC分类号： A61M5/32

    CPC分类号： A61M25/0069 ,  A61M2025/0057 ,  A61M2025/1093

    摘要： A catheter is disclosed that has a detachable tip for delivery of a therapeutic substance to a chronic total occlusion (CTO) within a body vessel. The tip is made from a biodegradable material and includes an active agent dispersed therethrough. The detachable tip pierces into the calcified lesion, detaches from the catheter, and remains embedded within the lesion as the tip degrades, thereby releasing the active agent. The active agent is a therapeutic substance effective to treat of a CTO. The active agent may be a drug, an enzyme, bacteria, or a parasite that degrades or softens the calcified lesion.

    摘要翻译： 公开了一种导管，其具有用于将治疗物质递送至体内容器内的慢性完全闭塞（CTO）的可拆卸末端。 尖端由可生物降解的材料制成并且包括分散在其中的活性剂。 可拆卸的尖端刺入钙化的病变，从导管分离，并且随着尖端降解而保持嵌入损伤内，从而释放活性剂。 活性剂是有效治疗CTO的治疗物质。 活性剂可以是降解或软化钙化病变的药物，酶，细菌或寄生虫。

    Responsivity correction for electro-optical imagers
    8.
    发明申请
    Responsivity correction for electro-optical imagers 有权
    电光成像仪的响应校正

    公开(公告)号：US20070229681A1

    公开(公告)日：2007-10-04

    申请号：US11393989

    申请日：2006-03-30

    申请人： Christopher Leddy ,  Robert Coda ,  Johnny Lee ,  Stephen Nash

    发明人： Christopher Leddy ,  Robert Coda ,  Johnny Lee ,  Stephen Nash

    IPC分类号： H04N5/217

    CPC分类号： H04N5/217

    摘要： An imaging system and method with an arrangement for sensing the performance of an optical system and providing data in response thereto and electronically correcting nonuniformity in the performance of the optical system in response thereto. In the illustrative application, the nonuniformity is a porthole effect. In the preferred embodiment, the arrangement for correcting includes an arrangement for providing an inverse distortion to an output of the system electronically. The inverse distortion is applied by generating a plurality of spatial correction coefficients from the performance data, storing the coefficients and applying the coefficients to current data from the optical system. The spatial correction coefficients are statistically generated gain and level correction defect maps. The present teachings should enable a correction of optical distortion in nonideal electro-optical systems without requiring additional optics.

    摘要翻译： 一种成像系统和方法，具有用于感测光学系统的性能并且响应于其提供数据并且电子地校正光学系统响应于其的性能的不均匀性的装置。 在说明性应用中，不均匀性是舷窗效应。 在优选实施例中，用于校正的装置包括用于以电子方式向系统的输出提供反变形的装置。 通过从性能数据产生多个空间校正系数，存储系数并将系数应用于来自光学系统的当前数据来应用逆失真。 空间校正系数是统计生成的增益和电平校正缺陷图。 本教导应能够校正非理想电光学系统中的光学失真，而不需要额外的光学器件。

    SHAFTS WITH PRESSURE RELIEF IN CRYOTHERAPEUTIC CATHETERS AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS
    9.
    发明申请
    SHAFTS WITH PRESSURE RELIEF IN CRYOTHERAPEUTIC CATHETERS AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS 有权
    在压力导管和相关装置，系统和方法中的压力释放

    公开(公告)号：US20130289549A1

    公开(公告)日：2013-10-31

    申请号：US13458120

    申请日：2012-04-27

    申请人： Stephen Nash ,  Grace Kelly

    发明人： Stephen Nash ,  Grace Kelly

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02 ,  A61B90/03 ,  A61B2018/00005 ,  A61B2018/00023 ,  A61B2018/00166 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268 ,  A61B2090/032 ,  A61B2090/037 ,  A61M25/1006 ,  A61M25/10184 ,  A61M25/1025 ,  A61M2025/1061 ,  F04C2270/041

    摘要： Cryotherapeutic systems with features that can facilitate pressure relief in the event of exhaust-passage blockage and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment can include an elongated shaft having a distal portion and a pressure-relief portion proximal to the distal portion. The cryotherapeutic system can further include a supply lumen, an exhaust passage, and a balloon configured to receive refrigerant from the supply lumen and to exhaust refrigerant to the exhaust passage. The pressure-relief portion can be configured to release refrigerant from the exhaust passage when a pressure of refrigerant in the exhaust passage exceeds a threshold pressure less than a pressure rating of the balloon. The pressure-relief portion, for example, can include a rupture element configured to rupture at about the threshold pressure.

    摘要翻译： 本文公开了具有能够促进在排气通道堵塞的情况下的压力释放以及相关的装置，系统和方法的特征的冷冻治疗系统。 根据特定实施例构造的冷冻治疗系统可以包括细长轴，其具有远侧部分和靠近远端部分的压力释放部分。 冷冻治疗系统还可以包括供应管腔，排气通道和被配置为从供应管腔接纳制冷剂并将制冷剂排出到排气通道的气囊。 当排气通道中的制冷剂的压力超过小于气囊的额定压力的阈值压力时，减压部分可被构造成从排气通道释放制冷剂。 例如，减压部分可以包括构造成在约阈值压力下破裂的断裂元件。