Cream for stimulating mitochondrial activity in the skin
    2.
    发明授权
    Cream for stimulating mitochondrial activity in the skin 有权
    用于刺激皮肤线粒体活性的霜剂

    公开(公告)号:US08435547B2

    公开(公告)日:2013-05-07

    申请号:US11512771

    申请日:2006-08-30

    IPC分类号: A61K8/37 A61K8/00 A61K8/368

    摘要: A skin care composition is useful for augmenting cellular metabolism in skin cells and thereby enhancing the regulation of intracellular signaling. The composition comprises a primer for skin cell mitochondrial function, such as a Krebs cycle intermediate, a precursor of a Krebs cycle intermediate, salts or esters thereof, or combinations thereof. The composition may also include antioxidants for free radical regulation and a pharmaceutically acceptable topical vehicle, such as an emollient base for skin health. A method for stimulating the mitochondrial activity of skin cells comprises administering to the skin of a person in need thereof a composition as described herein.

    摘要翻译: 皮肤护理组合物可用于增加皮肤细胞中的细胞代谢,从而增强细胞内信号传导的调节。 该组合物包含用于皮肤细胞线粒体功能的引物,例如克雷伯循环中间体,克雷伯循环中间体的前体,其盐或酯或其组合。 组合物还可以包括用于自由基调节的抗氧化剂和药学上可接受的局部赋形剂,例如用于皮肤健康的润肤剂基质。 用于刺激皮肤细胞的线粒体活性的方法包括向有需要的人的皮肤施用如本文所述的组合物。

    Anti-aging cream
    3.
    发明申请
    Anti-aging cream 有权
    抗衰老霜

    公开(公告)号:US20080057088A1

    公开(公告)日:2008-03-06

    申请号:US11512771

    申请日:2006-08-30

    IPC分类号: A61K8/02 A61K31/225 A61K8/37

    摘要: A skin care composition is useful for augmenting cellular metabolism in skin cells and thereby enhancing the regulation of intracellular signaling. The composition comprises a primer for skin cell mitochondrial function, such as a Krebs cycle intermediate, a precursor of a Krebs cycle intermediate, salts or esters thereof, or combinations thereof. The composition may also include antioxidants for free radical regulation and a pharmaceutically acceptable topical vehicle, such as an emollient base for skin health. A method for stimulating the mitochondrial activity of skin cells comprises administering to the skin of a person in need thereof a composition as described herein.

    摘要翻译: 皮肤护理组合物可用于增加皮肤细胞中的细胞代谢,从而增强细胞内信号传导的调节。 该组合物包含用于皮肤细胞线粒体功能的引物,例如克雷伯循环中间体,克雷伯循环中间体的前体,其盐或酯或其组合。 组合物还可以包括用于自由基调节的抗氧化剂和药学上可接受的局部赋形剂,例如用于皮肤健康的润肤剂基质。 用于刺激皮肤细胞的线粒体活性的方法包括向有需要的人的皮肤施用如本文所述的组合物。

    Composite structure including a low vinyl acetate layer
    5.
    发明申请
    Composite structure including a low vinyl acetate layer 审中-公开
    复合结构包括低乙酸乙烯酯层

    公开(公告)号:US20060127463A1

    公开(公告)日:2006-06-15

    申请号:US11013131

    申请日:2004-12-15

    IPC分类号: A61F13/02 A61L15/16

    CPC分类号: A61K9/703 A61K9/7084

    摘要: A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer. A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.

    摘要翻译: 适于制备透皮递送装置的复合结构包括:(a)衬垫膜层; (b)包含乙酸乙烯酯重复单元含量为零至15重量%的容纳层,所述层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分与非极性聚合物的组合; 和(c)厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物,其中嵌段共聚物的A链段是苯乙烯链段。 基于不包括任何溶剂的组合物的总重量,该组合物包含1至15重量%的乙酸乙烯酯重复单元。