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公开(公告)号：US20240026314A1
公开(公告)日：2024-01-25
申请号：US18254593
申请日：2021-11-24
Applicant: Steven ROTHSTEIN , Tariq AKHTAR , Jose CASARETTO , Colby PERRIN , Kristen VAN GELDER
Inventor： Steven ROTHSTEIN , Tariq AKHTAR , Jose CASARETTO , Colby PERRIN , Kristen VAN GELDER
CPC classification number: C12N9/1085 , C12N9/1011 , C12P7/22 , C12N15/63 , A61K8/347
Abstract: Described herein is a polypeptide encoding a prenyltransferase for prenylating a polyphenol and a polypeptide encoding an O-methyltransferase for methylating a polyphenol. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or a polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or the polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a fragment of the polypeptide or the variant thereof.
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2.发明授权公开(公告)号：US08742201B2
公开(公告)日：2014-06-03
申请号：US12775265
申请日：2010-05-06
Applicant: Steven Rothstein , Yong-Mei Bi
Inventor： Steven Rothstein , Yong-Mei Bi
CPC classification number: C07K14/415 , C12N15/8242 , C12N15/8243 , C12N15/8245 , C12N15/8261 , Y02A40/146
Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
Abstract translation: 本发明涉及用于糖感测所需的氮调节的GATA转录因子基因，并且该基因的表达调节调节植物特征。 本发明的GATA转录因子参与调节植物中的糖感测，其表达受氮状态的影响。 这种或基本相似的基因的增加的表达可以产生具有改善的氮利用率和增加的产量的植物。
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3.发明申请公开(公告)号：US20090276919A1
公开(公告)日：2009-11-05
申请号：US12494171
申请日：2009-06-29
Applicant: Steven Rothstein , Yong-Mei Bi
Inventor： Steven Rothstein , Yong-Mei Bi
CPC classification number: C12N15/8242 , C07K14/415 , C12N15/8243 , C12N15/8245 , C12N15/8261 , Y02A40/146
Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
Abstract translation: 本发明涉及用于糖感测所需的氮调节的GATA转录因子基因，并且该基因的表达调节调节植物特征。 本发明的GATA转录因子参与调节植物中的糖感测，其表达受氮状态的影响。 这种或基本相似的基因的增加的表达可以产生具有改善的氮利用率和增加的产量的植物。
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4.发明申请公开(公告)号：US20090075868A1
公开(公告)日：2009-03-19
申请号：US12149645
申请日：2008-05-06
Applicant: Fred Keeley , Aser Rothstein , Steven Rothstein , Kimberly Woodhouse
Inventor： Fred Keeley , Aser Rothstein , Steven Rothstein , Kimberly Woodhouse
IPC: A61K38/16 , A61K31/726
CPC classification number: A61K38/39 , A61K38/17 , A61L27/227
Abstract: In joint reconstruction, repair and cushioning applications, a synthetic polypeptide material is useful that contains cross-linked polypeptides that are modeled on human elastin or other fibrous proteins. The polypeptides comprise at least three consecutive beta-sheet/beta-turn structures and at least one amino acid residue that participates in cross-linking.
Abstract translation: 在关节重建，修复和缓冲应用中，合成多肽材料是有用的，其含有模拟人弹性蛋白或其它纤维蛋白的交联多肽。 多肽包含至少三个连续的β-折叠/β-转角结构和参与交联的至少一个氨基酸残基。
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5.发明申请公开(公告)号：US20070250956A1
公开(公告)日：2007-10-25
申请号：US11736017
申请日：2007-04-17
Applicant: Steven Rothstein , Yong-Mei Bi
Inventor： Steven Rothstein , Yong-Mei Bi
CPC classification number: C07K14/415 , C12N15/8242 , C12N15/8243 , C12N15/8245 , C12N15/8261 , Y02A40/146
Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
Abstract translation: 本发明涉及用于糖感测所需的氮调节的GATA转录因子基因，并且该基因的表达调节调节植物特征。 本发明的GATA转录因子参与调节植物中的糖感测，其表达受氮状态的影响。 这种或基本相似的基因的增加的表达可以产生具有改善的氮利用率和增加的产量的植物。
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Patent Agency Ranking
6.发明授权公开(公告)号：US06765086B2
公开(公告)日：2004-07-20
申请号：US09964662
申请日：2001-09-28
Applicant: Aser Rothstein , Fred Keeley , Steven Rothstein
Inventor： Aser Rothstein , Fred Keeley , Steven Rothstein
IPC: A61K3800
CPC classification number: A61K8/65 , A61K8/64 , A61K38/00 , A61K2800/70 , A61K2800/86 , A61L27/34 , A61L31/10 , A61Q19/00 , C07K14/78 , Y10S977/915 , C08L89/00
Abstract: A polypeptide is provided that has a secondary structure characterized by at least three beta-sheet/beta-turn structures, and that is not a naturally occurring fibrous protein. Such polypeptides, illustrated by one modeled on elastin, are useful in prosthesis.
Abstract translation: 提供了具有特征在于至少三个β-折叠/β-转角结构并且不是天然存在的纤维蛋白质的二级结构的多肽。 由弹性蛋白模拟的一种所示的多肽可用于假体。
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7.发明授权公开(公告)号：US06489446B1
公开(公告)日：2002-12-03
申请号：US09340736
申请日：1999-06-29
Applicant: Aser Rothstein , Fred Keeley , Steven Rothstein
Inventor： Aser Rothstein , Fred Keeley , Steven Rothstein
IPC: A61K3800
CPC classification number: A61K8/65 , A61K8/64 , A61K38/00 , A61K2800/70 , A61K2800/86 , A61L27/34 , A61L31/10 , A61Q19/00 , C07K14/78 , Y10S977/915 , C08L89/00
Abstract: A polypeptide is provided that has a secondary structure characterized by at least three beta-sheet/beta-turn structures, and that is not a naturally occurring fibrous protein. Such polypeptides, illustrated by one modeled on elastin, are useful in prosthesis.
Abstract translation: 提供了具有特征在于至少三个β-折叠/β-转角结构并且不是天然存在的纤维蛋白质的二级结构的多肽。 由弹性蛋白模拟的一种所示的多肽可用于假体。
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8.发明授权公开(公告)号：US08119598B2
公开(公告)日：2012-02-21
申请号：US12149645
申请日：2008-05-06
Applicant: Fred Keeley , Aser Rothstein , Steven Rothstein , Kimberly Woodhouse
Inventor： Fred Keeley , Aser Rothstein , Steven Rothstein , Kimberly Woodhouse
CPC classification number: A61K38/39 , A61K38/17 , A61L27/227
Abstract: In joint reconstruction, repair and cushioning applications, a synthetic polypeptide material is useful that contains cross-linked polypeptides that are modeled on human elastin or other fibrous proteins. The polypeptides comprise at least three consecutive beta-sheet/beta-turn structures and at least one amino acid residue that participates in cross-linking.
Abstract translation: 在关节重建，修复和缓冲应用中，合成多肽材料是有用的，其含有模拟人弹性蛋白或其它纤维蛋白的交联多肽。 多肽包含至少三个连续的β-折叠/β-转角结构和参与交联的至少一个氨基酸残基。
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9.发明申请NITROGEN LIMITATION ADAPTABILITY GENE AND PROTEIN AND MODULATION THEREOF 审中-公开NITROGEN限制适应性基因和蛋白质及其调节公开(公告)号：US20090328255A1
公开(公告)日：2009-12-31
申请号：US12304987
申请日：2007-06-13
Applicant: Steven Rothstein , Mingsheng Peng , Yong-Mei Bi
Inventor： Steven Rothstein , Mingsheng Peng , Yong-Mei Bi
CPC classification number: C12N15/8255 , C12N9/93 , C12N15/825 , C12N15/8261 , C12N15/8266 , C12N15/8271 , Y02A40/146
Abstract: The present invention relates to a nitrogen-regulated RING-like ubiquitin E3 ligase gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The RING-like ubiquitin E3 ligase of the present invention is involved in mediating nitrogen limitation adaptive responses in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
Abstract translation: 本发明涉及用于糖感测所需的氮调节的RING样泛素E3连接酶基因，并且该基因的表达调节调节植物特征。 本发明的RING样泛素E3连接酶涉及介导植物中氮限制适应性反应，其表达受氮状态的影响。 这种或基本相似的基因的增加的表达可以产生具有改善的氮利用率和增加的产量的植物。
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公开(公告)号：US20060179512A1
公开(公告)日：2006-08-10
申请号：US11331199
申请日：2006-01-13
Applicant: Steven Rothstein , Yong-Mei Bi
Inventor： Steven Rothstein , Yong-Mei Bi
CPC classification number: C12N15/8242 , C07K14/415 , C12N15/8243 , C12N15/8245 , C12N15/8261 , Y02A40/146
Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
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