Isolating method for umbilical cord blood-derived pluripotent stem cells expressing ZNF281

    公开(公告)号:US10584312B2

    公开(公告)日:2020-03-10

    申请号:US13257961

    申请日:2010-03-03

    摘要: The present invention relates to a method for isolating pluripotent/multipotent stem cells derived from umbilical cord blood, characterized by culturing mononuclear cells isolated from umbilical cord blood in a culture vessel containing fibronectin and then harvesting stem cells from the culture, the umbilical cord blood-derived pluripotent/multipotent stem cells isolated thereby; and a cell therapeutic agent containing the pluripotent/multipotent stem cells derived from umbilical cord blood or cells differentiated therefrom. The present invention also relates to a novel culture media for stem cells, a culture method for stem cells which is characterized by culturing and proliferating stem cells in the culture media, and a method for increasing sternness of stem cells which is characterized by a sphere culture or a three-dimensional culture of stem cells.

    Equine Amniotic Fluid-Derived Multipotent Stem Cells and a Method for Producing the Same
    2.
    发明申请
    Equine Amniotic Fluid-Derived Multipotent Stem Cells and a Method for Producing the Same 有权
    马氏羊血液衍生的多能干细胞及其生产方法

    公开(公告)号:US20130230924A1

    公开(公告)日:2013-09-05

    申请号:US13821303

    申请日:2011-09-07

    IPC分类号: C12N5/071 C12N5/0735

    摘要: The present invention relates to equine amniotic fluid-derived multipotent stem cells (eAF-MSCs) and a preparation method thereof. More particularly, the present invention relates to equine amniotic fluid-derived multipotent stem cells which exhibit all negative immunological characteristics with respect to the human markers, CD19, CD20, CD28, CD31, CD34, CD38, CD41a, CD62L, CD62P and CD200, and exhibit all positive immunological characteristics with respect to the human markers, CD44, CD90 and CD105, and have the ability to differentiate into ectoderm, mesoderm or endoderm-derived cells.The present invention confirmed that equine amniotic fluid can be a source of equine adult multipotent stem cell supply, and the equine amniotic fluid-derived multipotent stem cells exhibit excellent self-renewal ability and differentiation capability. Therefore, the cells can be used as an active ingredient for cell therapy of horses, which requires a large amount of cells. In particular, the stem cells of the present invention having excellent self-renewal ability and differentiation capability are useful for the treatment of bone, tendon, or muscle injuries and bone loss diseases of racehorses.

    摘要翻译: 本发明涉及马羊源多能干细胞(eAF-MSC)及其制备方法。 更具体地说,本发明涉及相对于人类标记物CD19,CD20,CD28,CD31,CD34,CD38,CD41a,CD62L,CD62P和CD200具有全部阴性免疫学特性的马羊羊多能干细胞,以及 相对于人类标志物CD44,CD90和CD105显示出所有阳性免疫学特征,并具有分化成外胚层,中胚层或内胚层衍生细胞的能力。 本发明证实马羊水可以成为马成人多能干细胞供应的来源,马羊羊多能干细胞表现出优异的自我更新能力和分化能力。 因此,细胞可以用作用于马的细胞治疗的活性成分,其需要大量的细胞。 特别地,本发明的具有优异的自我更新能力和分化能力的干细胞可用于治疗赛马的骨骼,肌腱或肌肉损伤和骨丢失疾病。

    ">
    3.
    发明申请
    "Pharmaceutical Composition Comprising Stem Cells Treated with NOD2 Agonist or Culture Thereof for Prevention and Treatment of Immune Disorders and Inflammatory Diseases" 有权
    “包含用NOD2激动剂治疗的干细胞的药物组合物或其免疫疾病和炎症疾病的预防和治疗”

    公开(公告)号:US20130209422A1

    公开(公告)日:2013-08-15

    申请号:US13818234

    申请日:2011-08-19

    IPC分类号: A61K35/28

    摘要: The present invention relates to a pharmaceutical composition for the prevention or treatment of immune disorders and inflammatory diseases, comprising stem cells that are generated by culturing stem cells expression Nucleotide-binding Oligomerization Domain protein 2 (NOD2) with a NOD2 agonist or a culture thereof. More particularly, the present invention relates to a method for suppressing immune responses or inflammatory responses of a subject, comprising the step of administering the pharmaceutical composition, the stem cells or culture thereof to the subject, a method for preparing an immunosuppressive drug or an anti-inflammatory drug using the stem cells or culture thereof, a method for preparing PGE2 or TGF-β1 comprising the step of culturing NOD2-expressing stem cells in culture medium with a NOD2 agonist, a graft comprising stem cells expressing NOD2 and the NOD2 agonist, a method for preparing the graft, a composite comprising stem cells expressing NOD2 and the NOD2 agonist, and a culture generated by culturing the NOD2-expressing stem cells with a NOD2 agonist.

    摘要翻译: 本发明涉及用于预防或治疗免疫疾病和炎性疾病的药物组合物,其包含通过用NOD2激动剂或其培养物培养干细胞表达核苷酸结合寡聚化结构域蛋白2(NOD2)而产生的干细胞。 更具体地,本发明涉及一种抑制受试者的免疫应答或炎症反应的方法,包括向受试者施用药物组合物,干细胞或培养物的步骤,制备免疫抑制药物或抗体的方法 使用干细胞或其培养物的炎症药物,制备PGE2或TGF-β1的方法,包括用NOD2激动剂培养培养基中培养表达NOD2的干细胞的步骤,包含表达NOD2的干细胞的移植物和NOD2激动剂, 制备移植物的方法,包含表达NOD2的干细胞和NOD2激动剂的复合物,以及通过用NOD2激动剂培养表达NOD2的干细胞产生的培养物。

    System and method for installing filtering membrane module to frame structure
    4.
    发明授权
    System and method for installing filtering membrane module to frame structure 有权
    过滤膜组件安装到框架结构的系统和方法

    公开(公告)号:US08506805B2

    公开(公告)日:2013-08-13

    申请号:US12682583

    申请日:2008-10-09

    IPC分类号: B01D29/00 B01D35/30

    摘要: A system and method for installing a large-sized filtering membrane module to a frame structure with easiness is disclosed, wherein the system comprises a frame structure to which the filtering membrane module is to be installed; and an installing apparatus for installing the filtering membrane module to the frame structure, wherein the installing apparatus comprises a horizontal rod parallel to an inserting direction of the filtering membrane module into the frame structure; and a moving unit movable toward the frame structure along the horizontal rod while supporting the filtering membrane module.

    摘要翻译: 公开了一种将大型过滤膜组件安装到框架结构的系统和方法,其中系统包括要安装过滤膜组件的框架结构; 以及用于将过滤膜组件安装到框架结构的安装装置,其中安装装置包括平行于过滤膜组件插入框架结构的插入方向的水平杆; 以及移动单元,其在支撑过滤膜组件的同时沿着水平杆向框架结构移动。

    WASHING MACHINE HAVING BALANCER
    5.
    发明申请
    WASHING MACHINE HAVING BALANCER 有权
    洗衣机有平衡机

    公开(公告)号:US20120144876A1

    公开(公告)日:2012-06-14

    申请号:US13402282

    申请日:2012-02-22

    IPC分类号: D06F37/22 D06F21/02

    CPC分类号: D06F37/225

    摘要: A front loading washing machine including a housing; a water reservoir installed in the housing to contain washing water; a spin tub provided in the water reservoir to hold laundry to be washed, the spin tub rotatable with respect to a horizontal axis of the washing machine, the spin tub including a cylindrical body, a front cover and a rear cover, the front cover having a front wall with an opening formed therein for receiving laundry and an annular recess having a predefined depth formed in the front wall of the front cover such that an outer annular side wall defining the annular recess establishes direct physical contact with a predefined area of an inner surface of the cylindrical body; and at least one balancer installed in the annular recess of the spin tub, the balancer comprising an annular shaped race formed of a plastic material.

    摘要翻译: 一种包括壳体的前装式洗衣机; 一个安装在外壳内以容纳洗涤水的储水器; 设置在所述储水器中以保持要洗涤的衣物的旋转桶,所述旋转桶相对于所述洗衣机的水平轴线可旋转,所述旋转桶包括圆筒体,前盖和后盖,所述前盖具有 具有形成在其中用于接收衣物的开口的前壁和形成在前盖的前壁中的预定深度的环形凹部,使得限定环形凹部的外环形侧壁与内部的预定区域形成直接的物理接触 圆柱体表面; 以及安装在旋转桶的环形凹部中的至少一个平衡器,该平衡器包括由塑料材料形成的环形圈。

    Memory structures and methods for video codec
    6.
    发明授权
    Memory structures and methods for video codec 有权
    视频编解码器的内存结构和方法

    公开(公告)号:US08180195B2

    公开(公告)日:2012-05-15

    申请号:US12071857

    申请日:2008-02-27

    IPC分类号: H04N7/12

    CPC分类号: H04N19/423 H04N19/61

    摘要: A memory device for storing a plurality of macroblocks may include a plurality of memory banks. Each macroblock may include m*n pixel data, wherein m is a positive integer, and wherein n also is a positive integer. The plurality of memory banks is adapted to store the pixel data, and wherein each memory bank is sized to store rows of m pixel data. An image processing system may include: a memory adapted to store a plurality of macroblocks; and a video codec. The memory may include a plurality of memory banks. Each memory bank may be sized to store rows of m pixel data. The video codec may be adapted to encode pixel data read from the memory. The video codec also may be adapted to decode the pixel data read from the memory.

    摘要翻译: 用于存储多个宏块的存储器件可以包括多个存储器组。 每个宏块可以包括m * n像素数据,其中m是正整数,并且其中n也是正整数。 多个存储体适于存储像素数据,并且其中每个存储体的大小设置为存储m个像素数据的行。 图像处理系统可以包括:适于存储多个宏块的存储器; 和视频编解码器。 存储器可以包括多个存储体。 每个存储体可以被设计成存储m个像素数据的行。 视频编解码器可以适于编码从存储器读取的像素数据。 视频编解码器也可以适于对从存储器读取的像素数据进行解码。

    Motor and recording disc drive apparatus
    8.
    发明申请
    Motor and recording disc drive apparatus 失效
    电机和记录盘驱动装置

    公开(公告)号:US20110304937A1

    公开(公告)日:2011-12-15

    申请号:US12926294

    申请日:2010-11-08

    申请人: Sang Sun Kang

    发明人: Sang Sun Kang

    IPC分类号: G11B17/02 H02K7/08

    摘要: Disclosed are a motor and a recording disc drive apparatus that can prevent a fluid in a fluid dynamic bearing from being discharged to the outside. A motor according to an aspect of the invention may include: a shaft; a sleeve having a cylindrical shape and supporting the shaft such that the shaft is rotatable therein; a rotor case engaged with an upper end of the shaft and having a rotor main wall having a cylindrical shape and protruding from one surface thereof in order to receive part of the sleeve; and a cover engaged with an end portion of the rotor main wall and extending the rotor main wall, wherein at least two sealing portions preventing leaks of a fluid used to lubricate the sleeve are formed between an internal circumferential surface, defined by the rotor main wall and the cover, and an outer circumferential surface of the sleeve.

    摘要翻译: 公开了一种能够防止流体动力轴承中的流体被排出到外部的马达和记录盘驱动装置。 根据本发明的一个方面的电动机可以包括:轴; 套筒,其具有圆柱形并支撑所述轴,使得所述轴可旋转; 转子壳体与轴的上端接合并且具有圆柱形形状并从其一个表面突出的转子主壁,以便容纳套筒的一部分; 以及与转子主壁的端部接合并且延伸转子主壁的盖,其中,在由转子主壁限定的内周面之间形成有防止用于润滑套筒的流体泄漏的至少两个密封部 和外壳,以及套筒的外周面。

    Video codecs, data processing systems and methods for the same
    9.
    发明授权
    Video codecs, data processing systems and methods for the same 失效
    视频编解码器,数据处理系统和方法相同

    公开(公告)号:US07986734B2

    公开(公告)日:2011-07-26

    申请号:US11018762

    申请日:2004-12-22

    申请人: Jung-Sun Kang

    发明人: Jung-Sun Kang

    IPC分类号: H04N7/18

    摘要: Exemplary embodiments of the present invention provide a data processing system which may include a task scheduler for enabling a plurality of independent data processing units to be operable in pipelining streams and/or controlling pipelined operations to be differentiated by tasks, and a memory pool for storing data from the data processing units. The data processing units may perform tasks in response to task start signals provided from the task scheduler. The data processing units may complete the tasks as instructed by the task scheduler, transmit task end signals to the scheduler and transition into standby states.

    摘要翻译: 本发明的示例性实施例提供一种数据处理系统,其可以包括任务调度器,用于使多个独立的数据处理单元能够在流水线中流动管理和/或控制由任务区分的流水线操作,以及用于存储的存储器池 来自数据处理单元的数据。 数据处理单元可以响应于从任务调度器提供的任务开始信号执行任务。 数据处理单元可以按任务调度器的指示完成任务,将任务结束信号发送到调度器并转换到待机状态。

    Washing machine having balancer
    10.
    发明授权
    Washing machine having balancer 有权
    洗衣机有平衡机

    公开(公告)号:US07942026B2

    公开(公告)日:2011-05-17

    申请号:US12801952

    申请日:2010-07-02

    IPC分类号: D06F35/00

    CPC分类号: D06F37/225

    摘要: A washing machine that has at least one balancer that increases durability by reinforcing the strength of the balancer and is installed on a rotating tub in a rapid and convenient way. The balancer includes first and second housings that have an annular shape and are fused to form a closed internal space, and the first housing including at least one support for reinforcing the strength of the balancer. A spin tub includes an annular recess corresponding to the balancer so as to be coupled with the balancer. The support protrudes from the first housing and comes into contact with a wall of the recess and guides the balancer to be maintained in the recess in place. The supports are integrally molded to the first housing at predetermined intervals along at least a first wall of the first housing.

    摘要翻译: 一种具有至少一个平衡器的洗衣机,其通过增强平衡器的强度而增加耐久性,并以快速和方便的方式安装在旋转桶上。 平衡器包括具有环形形状并被熔合以形成封闭的内部空间的第一和第二壳体,并且第一壳体包括用于增强平衡器的强度的至少一个支撑件。 旋转浴缸包括对应于平衡器的环形凹部,以便与平衡器相连。 支撑件从第一壳体突出并且与凹部的壁接触并且引导平衡器以保持在凹部中的适当位置。 支撑件沿着第一壳体的至少第一壁以预定间隔一体地模制到第一壳体。