公开(公告)号：US20090076481A1

公开(公告)日：2009-03-19

申请号：US12076846

申请日：2008-03-24

申请人： THOMAS J. STEGMANN ,  KENNETH A. THOMAS ,  JOHN W. JACOBS ,  TUGAN MUFTULER ,  SHADFAR BAHRI ,  HON YU ,  VANCE GARDNER

发明人： THOMAS J. STEGMANN ,  KENNETH A. THOMAS ,  JOHN W. JACOBS ,  TUGAN MUFTULER ,  SHADFAR BAHRI ,  HON YU ,  VANCE GARDNER

IPC分类号： A61M5/00 ,  A61B5/05

CPC分类号： A61K38/204 ,  A61K38/1709 ,  A61K38/18 ,  A61K38/1808 ,  A61K38/1825 ,  A61K38/1833 ,  A61K38/185 ,  A61K38/1858 ,  A61K38/1866 ,  A61K38/1875 ,  A61K38/1891 ,  A61K38/19 ,  A61K38/193 ,  A61K38/2006 ,  A61K38/22 ,  G01N33/74 ,  G01N33/84 ,  G01N2333/50 ,  G01N2333/96486 ,  G01N2800/10 ,  G01N2800/105

摘要： The invention relates to methods for the diagnosis, amelioration, and treatment of back pain, particularly lumbar back pain, in particular, back pain caused by muscular abnormalities, vertebral body osteoporosis, and disc degeneration. Patients with back pain are categorized into specific subsets that are deemed to have potential to respond to therapy. In particular, the invention includes a therapy involving stimulation of neovascularization so as to increase perfusion of various spine compartments.

摘要翻译： 本发明涉及用于诊断，改善和治疗背痛，特别是腰背痛的方法，特别是由肌肉异常，椎体骨质疏松症和椎间盘退变引起的背痛。 患有背痛的患者被分类为被认为有可能对治疗有反应的特定子集。 特别地，本发明包括涉及刺激新血管形成以增加各种脊柱隔室的灌注的疗法。

公开(公告)号：US08983570B2

公开(公告)日：2015-03-17

申请号：US12076846

申请日：2008-03-24

申请人： Thomas J. Stegmann ,  Kenneth A. Thomas ,  John W. Jacobs ,  Tugan Muftuler ,  Shadfar Bahri ,  Hon Yu ,  Vance Gardner

发明人： Thomas J. Stegmann ,  Kenneth A. Thomas ,  John W. Jacobs ,  Tugan Muftuler ,  Shadfar Bahri ,  Hon Yu ,  Vance Gardner

IPC分类号： A61B5/05 ,  G01N33/74 ,  G01N33/84 ,  A61K38/17 ,  A61K38/18

CPC分类号： A61K38/204 ,  A61K38/1709 ,  A61K38/18 ,  A61K38/1808 ,  A61K38/1825 ,  A61K38/1833 ,  A61K38/185 ,  A61K38/1858 ,  A61K38/1866 ,  A61K38/1875 ,  A61K38/1891 ,  A61K38/19 ,  A61K38/193 ,  A61K38/2006 ,  A61K38/22 ,  G01N33/74 ,  G01N33/84 ,  G01N2333/50 ,  G01N2333/96486 ,  G01N2800/10 ,  G01N2800/105

摘要： The invention relates to methods for the diagnosis, amelioration, and treatment of back pain, particularly lumbar back pain, in particular, back pain caused by muscular abnormalities, vertebral body osteoporosis, and disc degeneration. Patients with back pain are categorized into specific subsets that are deemed to have potential to respond to therapy. In particular, the invention includes a therapy involving stimulation of neovascularization so as to increase perfusion of various spine compartments.