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1.发明授权
公开(公告)号：US5330830A
公开(公告)日：1994-07-19
申请号：US868135
申请日：1992-04-14
申请人： Takao Miyamori , Kazuaki Hayashida , Jun Kamo
发明人： Takao Miyamori , Kazuaki Hayashida , Jun Kamo
CPC分类号： B01D67/0088 , B01D67/0093 , B01D2323/02 , B01D2323/30 , Y10T428/249953
摘要： A heat-resisting porous membrane comprises a porous polyolefin membrane having a crosslinked copolymer held on at least a part of the pore surfaces thereof, the crosslinked copolymer being composed of a monomer (A) comprising at least one multifunctional (meth)acrylate and a monomer (B) comprising at least one monofunctional (meth)acrylate having a hydrocarbon radical of 5 to 20 carbon atoms; and the heat-resisting porous membrane can be hydrophilized by additionally having a crosslinked polymer thereon. These heat-resisting porous membranes can be used in hot water for a long period of time without deteriorating the mechanical properties inherently possessed by the matrix of the porous membrane.
摘要翻译： 耐热多孔膜包括具有保留在其孔表面的至少一部分上的交联共聚物的多孔聚烯烃膜，所述交联共聚物由包含至少一种多官能（甲基）丙烯酸酯和单体的单体（A）组成， （B）包含至少一种具有5至20个碳原子的烃基的单官能（甲基）丙烯酸酯; 并且通过在其上另外具有交联聚合物，可以使耐热多孔膜亲水化。 这些耐热多孔膜可以长期在热水中使用，而不会降低多孔膜基体固有的机械性能。
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公开(公告)号：US5403483A
公开(公告)日：1995-04-04
申请号：US94981
申请日：1993-07-22
申请人： Kazuaki Hayashida , Takao Miyamori , Jun Kamo
发明人： Kazuaki Hayashida , Takao Miyamori , Jun Kamo
CPC分类号： B01D67/0088 , B01D39/083 , B01D2239/04 , B01D2239/0428 , B01D2239/0464 , B01D2239/0471 , B01D2239/0618
摘要： Disclosed is a hydrophobic porous membrane with a polymer having fluorinated alkyl side chains held in physical contact with the surface of a polyolefin porous membrane in which the fluorinated alkyl side chains of the polymer are crystallized, as well as its manufacturing process. Also disclosed is a hydrophobic porous membrane with a fluorinated crosslinked polymer from a fluorinated monomer with a fluorinated alkyl side chain and a crosslinking monomer held in physical contact with the surface of a polyolefin porous membrane, in which the fluorinated alkyl side chains of the fluorinated crosslinked polymer are crystallized, as well as its manufacturing process. These porous membranes use polyolefin porous membranes having a higher mechanical strength and lower costs than the fluorinated polymer porous membranes and still provide superior hydrophobicity over polytetrafluoroethylene type membranes.
摘要翻译： 公开了具有氟化烷基侧链与聚烯烃多孔膜的表面物理接触的聚合物的疏水性多孔膜，其中聚合物的氟化烷基侧链结晶，以及其制造方法。 还公开了一种疏水多孔膜，其具有氟化单体与氟化烷基侧链的氟化交联聚合物，并且交联单体与聚烯烃多孔膜的表面保持物理接触，其中氟化交联的 聚合物结晶，以及其制造过程。 这些多孔膜使用的聚烯烃多孔膜具有比氟化聚合物多孔膜更高的机械强度和更低的成本，并且仍然优于聚四氟乙烯型膜的疏水性。
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公开(公告)号：US5149649A
公开(公告)日：1992-09-22
申请号：US561323
申请日：1990-08-01
摘要： A method for culturing cells by supplying oxygen to a culture medium through a multilayer composite membrane consisting of a porous layer(s) and a nonporous layer(s) having a thickness of less than 10 micrometers laminated one after the other. By using this multilayer composite membrane for supplying oxygen to the culture medium, oxygen can be supplied to the culture medium and/or the culture broth without causing foaming in the culture medium, cell growth inhibition or reduction in productivity of cellular products.
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4.发明授权Process for the preparation of organic esters of ascorbic acid or erythorbic acid using ester hydralases in organic solvents containing 100-10,000 ppm of water 失效在含有100-10,000 PPM水的有机溶剂中使用酯类水合物制备抗坏血酸或硫酸的有机酸的方法
公开(公告)号：US5079153A
公开(公告)日：1992-01-07
申请号：US531701
申请日：1990-06-01
IPC分类号： C12P17/04
CPC分类号： C12P17/04
摘要： A process for the preparation of an organic ester of ascorbic acid or erythorbic acid represented by the general formula (II) or (III): ##STR1## wherein R.sub.1 is alkyl, aralkyl, or aryl, by reacting ascorbic acid or erythorbic acid with an organic acid or an ester thereof of the general formula (I) :R.sub.1 COOR.sub.2 (I)wherein R.sub.1 is as defined above and R.sub.2 is hydrogen, methyl, ethyl or propyl, in an organic solvent in the presence of an ester hydrolase.
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5.发明授权
公开(公告)号：US5071753A
公开(公告)日：1991-12-10
申请号：US607676
申请日：1990-11-01
IPC分类号： C12P17/04
CPC分类号： C12P17/04
摘要： A process for the preparation of an organic ester of ascorbic acid or erythorbic acid represented by the general formula (II) or (III): ##STR1## wherein R.sub.1 is alkyl, aralkyl, or aryl, by reacting ascorbic acid or erythorbic acid with an organic acid or an ester thereof of the general formula (I):wherein R.sub.1 is as defined above and R.sub.2 is hydrogen, methyl, ethyl or propyl, in an organic solvent in the presence of an ester hydrolase.
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公开(公告)号：US4885244A
公开(公告)日：1989-12-05
申请号：US104219
申请日：1987-10-05
申请人： Takao Miyamori , Ryozo Numazawa , Akihiro Sakimae , Hisao Onishi
发明人： Takao Miyamori , Ryozo Numazawa , Akihiro Sakimae , Hisao Onishi
CPC分类号： C08B37/0072 , C12P19/26 , Y10T436/188
摘要： High molecular weight hyaluronic acid can be efficiently produced by incorporating one or more compounds having at least one aromatic ring to which one or more hydroxyl groups are attached into a medium for producing hyaluronic acid by a bacterium capable of producing hyaluronic acid. By using this method, a sufficient amount of hyaluronic acid can be easily obtained without decomposing the high molecular structure of hyaluronic acid so that the process for isolating and purifying hyaluronic acid from the medium can be simplified.
摘要翻译： 高分子量透明质酸可以通过将一种或多种具有至少一个芳环的化合物（其中一个或多个羟基被连接到用于产生透明质酸的细菌的培养基中）而被能够产生透明质酸的细菌产生。 通过使用该方法，可以容易地获得足够量的透明质酸，而不会分解透明质酸的高分子结构，从而可以简化从培养基中分离和纯化透明质酸的方法。
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