Phase contrast observation device
    1.
    发明授权
    Phase contrast observation device 有权
    相位对比观察装置

    公开(公告)号:US06317261B1

    公开(公告)日:2001-11-13

    申请号:US09345164

    申请日:1999-06-30

    申请人: Tatsuro Otaki

    发明人: Tatsuro Otaki

    IPC分类号: G02B2106

    CPC分类号: G02B21/06 G02B21/14

    摘要: A phase contrast observation device for observing a phase object (O), and phase apertures for same. The device comprises, in order along an optical axis (AX), a light source (LS) capable of providing light (L), an illumination optical system (G2 and G3) for condensing the light and illuminating the object, an aperture stop (AP) having an aperture (AO) therein, arranged in the illumination optical system, an objective lens system (G2 and G3) for converging light from the illuminated object and forming an image of the object. The device also includes one of a number of novel phase apertures (Ph1-Ph4) arranged at a position inside said objective lens conjugate to the aperture stop. The phase apertures of the present invention allow for high-contrast and low-contrast imaging regardless of the phase content of the object.

    摘要翻译: 用于观察相位物体(O)的相位对比度观察装置及其相位孔径。 该装置沿着光轴(AX)依次包括能够提供光(L)的光源(LS),用于聚光并照亮物体的照明光学系统(G2和G3),孔径光阑 AP),布置在照明光学系统中的具有孔径(AO)的物镜系统(G2和G3),用于会聚来自被照射物体的光并形成物体的图像。 该装置还包括布置在与孔径光阑共轭的所述物镜内的位置处的许多新颖的相位孔径(Ph1-Ph4)中的一个。 本发明的相位孔径无论物体的相位含量如何,均允许高对比度和低对比度成像。

    Microscope system
    2.
    发明授权
    Microscope system 失效
    显微镜系统

    公开(公告)号:US06128128A

    公开(公告)日:2000-10-03

    申请号:US854465

    申请日:1997-05-12

    IPC分类号: G02B21/24 G02B21/02 G02B21/00

    CPC分类号: G02B21/02

    摘要: A microscope system for observing an image of a sample at desired magnifications includes a first objective lens having an objective side surface which is telecentric, a focusing lens, disposed in an optical path along which optical rays emitted from the first objective lens travel, for focusing the optical rays and forming a sample image and a second objective lens having a magnification factor different from that of the first objective lens. An interchanging member holds the first objective lens and the second objective lens and is used for placing one of the first and second objective lenses in an observational optical path between the sample and the focusing lens. The inequality 0.29

    摘要翻译: 用于以期望的倍率观察样品的图像的显微镜系统包括具有远心的物镜侧表面的第一物镜,设置在从第一物镜行进的光线穿过的光路中的聚焦透镜,用于聚焦 并且形成样本图像和具有与第一物镜不同的放大倍率的第二物镜。 交换构件保持第一物镜和第二物镜,并用于将第一和第二物镜之一放置在样品和聚焦透镜之间的观察光路中。 假设D为相当于样品的表面与物镜的附着面之间的距离的ff的焦距,fI为聚焦透镜的焦距,则满足不等式0.29

    Lens-barrel optical system and microscope apparatus
    3.
    发明授权
    Lens-barrel optical system and microscope apparatus 失效
    镜筒光学系统和显微镜装置

    公开(公告)号:US5847866A

    公开(公告)日:1998-12-08

    申请号:US694294

    申请日:1996-08-08

    申请人: Tatsuro Otaki

    发明人: Tatsuro Otaki

    CPC分类号: G02B21/361 G02B21/0088

    摘要: A microscope apparatus having an objective optical system for condensing a beam emitted from a sample to form an intermediate image; a lens-barrel optical system for focusing a beam from the intermediate image to form an observation image; and an eyepiece optical system for enlarging and projecting a beam from the observation image; wherein the lens-barrel optical system includes a relay lens system for focusing a beam from the intermediate image formed by the objective optical system to form the observation image and guiding a beam from the observation image to the eyepiece optical system; and a beam rotating unit having a plurality of reflecting members three-dimensionally arranged in an optical path between the objective optical system and the observation image, wherein the plurality of reflecting members successively reflect the beam from the objective optical system to invert the beam about an optical axis of the relay lens system, thereby forming the observation image in the form of an inverted image. This arrangement permits the lens-barrel optical system to form the inverted observation image as focusing the beam from the inverted intermediate image in the compact, easy, and cheap structure.

    摘要翻译: 一种显微镜装置,具有用于聚集从样本发射的光束以形成中间图像的物镜光学系统; 用于聚焦来自中间图像的光束以形成观察图像的透镜镜筒光学系统; 以及用于从观察图像放大和投影光束的目镜光学系统; 其中透镜镜筒光学系统包括用于聚焦来自由物镜光学系统形成的中间图像的光束以形成观察图像并将来自观察图像的光束引导到目镜光学系统的中继透镜系统; 以及光束旋转单元,其具有三维地布置在物镜光学系统和观察图像之间的光路中的多个反射部件,其中多个反射部件连续地反射来自物镜光学系统的光束, 中继透镜系统的光轴,从而以反转图像的形式形成观察图像。 这种布置允许透镜镜筒光学系统形成反转观察图像,将来自反转的中间图像的光束聚焦在紧凑,容易和便宜的结构中。

    Photographic apparatus with selectable photometric optical systems
    4.
    发明授权
    Photographic apparatus with selectable photometric optical systems 失效
    具有可选光度光学系统的摄影设备

    公开(公告)号:US5687416A

    公开(公告)日:1997-11-11

    申请号:US667601

    申请日:1996-06-21

    IPC分类号: G02B21/36 G03B7/08 G03B17/48

    摘要: The present invention relates to a photographic apparatus comprising a photometric system which can tolerate a wide range of change in contrast. This photographic apparatus attains, at least, a state in which an image from an optical instrument such as microscope can be photographed and a state in which the light intensity of the image formed by the optical instrument can be measured by the photometric system utilizing a light separated from incident light. This photometric system comprises a plurality of optical systems respectively having magnifications different from each other and a photosensor having a light receiving surface defined by a plurality of light intensity detectors, wherein these plurality of optical systems and plurality of detectors are intentionally selected so as to change the range of measurement of an image formed on the light receiving surface of the photosensor.

    摘要翻译: 本发明涉及一种包括能够容忍对比度的广泛变化的光度测量系统的照相设备。 该摄影装置至少可以获得可以拍摄诸如显微镜的光学仪器的图像的状态,并且可以通过利用光的光度系统来测量由光学仪器形成的图像的光强度的状态 与入射光分开。 该测光系统包括分别具有彼此不同的倍率的多个光学系统和具有由多个光强度检测器限定的光接收表面的光传感器,其中这些多个光学系统和多个检测器被有意地选择以便改变 在光传感器的光接收表面上形成的图像的测量范围。

    Inverted microscope having a variable stage position
    5.
    发明授权
    Inverted microscope having a variable stage position 有权
    倒置显微镜具有可变台位置

    公开(公告)号:US6160662A

    公开(公告)日:2000-12-12

    申请号:US321602

    申请日:1999-05-28

    摘要: An inverted microscope having a variable stage position, a compact size, excellent operability, and low cost. The inverted microscope includes a detachable stage unit to support a stage on which a specimen is positioned and to support an objective lens facing the specimen. A microscope housing supports the stage, and includes an imaging lens positioned to image a parallel light beam from the objective lens. An observation unit is positioned on the microscope housing to observe the image formed by the imaging lens. An illumination unit, positioned between the microscope housing and the stage unit, irradiates light having a predetermined wavelength toward the specimen, and includes a fluorescent light unit. The illumination unit is detachably mounted to the microscope housing, and the stage unit is detachably mounted to the illumination unit, and a height of the stage with respect to the microscope housing is variable. The height of the stage can be changed when the illumination unit between the microscope housing and the stage unit is removed.

    摘要翻译: 具有可变台位置,尺寸紧凑,可操作性好,成本低的倒置显微镜。 倒置显微镜包括可拆卸台单元,用于支撑放置样本的台,并支撑面向样品的物镜。 显微镜外壳支撑台,并且包括成像透镜,其定位成对来自物镜的平行光束成像。 观察单元位于显微镜壳体上以观察由成像透镜形成的图像。 位于显微镜壳体和台架单元之间的照明单元将具有预定波长的光照射到试样上,并且包括荧光灯单元。 照明单元可拆卸地安装到显微镜壳体上,并且台单元可拆卸地安装到照明单元,并且台架相对于显微镜外壳的高度是可变的。 当显微镜外壳和平台单元之间的照明单元被拆除时,可以改变舞台的高度。

    Condenser lens system for use in a microscope
    6.
    发明授权
    Condenser lens system for use in a microscope 失效
    电容透镜系统用于显微镜

    公开(公告)号:US5657166A

    公开(公告)日:1997-08-12

    申请号:US178847

    申请日:1994-01-07

    申请人: Tatsuro Otaki

    发明人: Tatsuro Otaki

    摘要: A condenser lens system to collect light from a light source to illuminate a sample, which comprises in a named order from the light source side, a front group of positive refracting power having at least one lens and a rear group of positive refracting power having at least a positive lens for liquid immersion located closest to the sample, the positive lens for liquid immersion having a flat surface on the sample side.

    摘要翻译: 一种聚光透镜系统,用于收集来自光源的光以照射样品,其包括来自光源侧的命名顺序,具有至少一个透镜的正折射率的正面组和正折射率的后组,其具有 用于最接近样品的液浸的最小正透镜,用于浸液的正透镜在样品侧具有平坦表面。

    Differential interference microscope apparatus and an observing method
using the same apparatus
    7.
    发明授权
    Differential interference microscope apparatus and an observing method using the same apparatus 失效
    差示干涉显微镜装置和使用相同装置的观察方法

    公开(公告)号:US5572359A

    公开(公告)日:1996-11-05

    申请号:US269125

    申请日:1994-06-30

    CPC分类号: G02B21/14 G02B21/00

    摘要: A differential interference microscope which includes a light source, a condenser optical system for condensing beams of light from the light source and illuminating an object with the beams of light, an objective optical system for converging the beams of light from the illuminated object and forming an image of the object, a pick-up device for photoelectrically detecting the image of the object, and a contrast enhancement circuit for enhancing a contrast of the image on the basis of an output signal of the pick-up device. A first polarizing element and a first birefringent element are disposed sequentially in an optical path between the light source and the object. The first polarizing element changes the beams of light from the light source into predetermined beams of polarized light. The first birefringent element separates the polarized light into an ordinary ray and an extraordinary ray. A second birefringent element and a second polarizing element are disposed sequentially in an optical path between the object and the image. The second birefringent element guides the two light beams from the object onto the same optical path. The second polarizing element causes the two light beams guided onto the same optical path to interfere with each other. The shear quantity S between the ordinary ray and the extraordinary ray satisfies the following condition:.delta./20.ltoreq.S

    摘要翻译: 一种差分干涉显微镜,包括光源,用于聚集来自光源的光束并用光束照射物体的聚光器光学系统,用于会聚来自被照射物体的光束的物镜光学系统,并形成 物体的图像,用于光电检测物体的图像的拾取装置,以及用于基于拾取装置的输出信号增强图像的对比度的对比度增强电路。 第一偏振元件和第一双折射元件依次设置在光源和物体之间的光路中。 第一偏振元件将来自光源的光束改变成预定的偏振光束。 第一双折射元件将偏振光分离成普通光线和非凡光线。 第二双折射元件和第二偏振元件依次设置在物体和图像之间的光路中。 第二双折射元件将来自物体的两个光束引导到相同的光路上。 第二偏振元件使引导到相同光路上的两个光束彼此干涉。 普通射线与非常光线之间的剪切量S满足以下条件:delta / 20

    Microscope having a pipette device
    8.
    发明授权
    Microscope having a pipette device 有权
    显微镜具有移液器装置

    公开(公告)号:US07092151B2

    公开(公告)日:2006-08-15

    申请号:US10889063

    申请日:2004-07-13

    IPC分类号: G02B21/00

    摘要: A well plate holding a specimen to be observed is placed on a fixed stage, and the specimen is observed through an objective lens disposed below the well plate. A well set on the optical axis is illuminated through transmitted illumination provided by a transmitted illumination device. The transmitted illumination device includes a plurality of LEDs disposed to form a ring shape, and a through hole is formed further inward relative to the LEDs. When injecting a reagent into the well being observed, the reagent is drawn by using a head at a pipette device, and then the head is moved to a point above the well being observed through the hole formed at the transmitted illumination device.

    摘要翻译: 将待观察的试样的孔板放置在固定台上,并通过设置在孔板下方的物镜观察样品。 通过由透射照明装置提供的透射照明照射光轴上的良好设置。 透射照明装置包括多个设置成环形的LED,并且相对于LED进一步向内形成通孔。 当将试剂注入观察到的井中时,通过在移液管装置上使用头部来吸取试剂,然后通过形成在透射照明装置上形成的孔将头移动到通过孔观察的点上。

    Focusing glass and photographic system
    9.
    发明授权
    Focusing glass and photographic system 失效
    聚焦玻璃和摄影系统

    公开(公告)号:US5802406A

    公开(公告)日:1998-09-01

    申请号:US801477

    申请日:1997-02-18

    IPC分类号: G03B13/24

    CPC分类号: G03B13/24

    摘要: A focusing glass and photographic system employing the same are disclosed. The photographic system includes an objective lens operable to form a real image of an object. The focusing glass is adapted to be situated at the real-image position, and comprises a semitransparent region surrounding a fully transmissive photographic zone. The photographic zone defines a region of the field of view of the objective (the field of view being viewable on the focusing screen) defining the metes and bounds of a photographic image obtainable using the photographic system.

    摘要翻译: 公开了一种聚焦玻璃和采用该聚焦玻璃的摄影系统。 摄影系统包括可操作以形成物体的真实图像的物镜。 聚焦玻璃适于位于实像位置,并且包括围绕完全透射照相区的半透明区域。 摄影区域限定了使用照相系统可获得的摄影图像的边界和界限的物镜视场的区域(可在聚焦屏幕上观看)。

    Microscope
    10.
    发明申请
    Microscope 有权
    显微镜

    公开(公告)号:US20050012990A1

    公开(公告)日:2005-01-20

    申请号:US10889063

    申请日:2004-07-13

    摘要: A well plate holding a specimen to be observed is placed on a fixed stage, and the specimen is observed through an objective lens disposed below the well plate. A well set on the optical axis is illuminated through transmitted illumination provided by a transmitted illumination device. The transmitted illumination device includes a plurality of LEDs disposed to form a ring shape, and a through hole is formed further inward relative to the LEDs. When injecting a reagent into the well being observed, the reagent is drawn by using a head at a pipette device, and then the head is moved to a point above the well being observed through the hole formed at the transmitted illumination device.

    摘要翻译: 将待观察的试样的孔板放置在固定台上,并通过设置在孔板下方的物镜观察样品。 通过由透射照明装置提供的透射照明照射光轴上的良好设置。 透射照明装置包括多个设置成环形的LED,并且相对于LED进一步向内形成通孔。 当将试剂注入观察到的井中时,通过在移液管装置上使用头部来吸取试剂,然后通过形成在透射照明装置上形成的孔将头移动到通过孔观察的点上。