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公开(公告)号：US08600479B2
公开(公告)日：2013-12-03
申请号：US12531808
申请日：2008-03-20
申请人： William D. Dalke , Kevin Lillehei , Thomas A. Jellison , Michael J. Gerber , James E. Matsuura , Stephen L Warren
发明人： William D. Dalke , Kevin Lillehei , Thomas A. Jellison , Michael J. Gerber , James E. Matsuura , Stephen L Warren
IPC分类号： A61B5/05
CPC分类号： A61K51/0491 , Y10T137/0402
摘要： A catheter system adapted for navigating, guiding and implanting a catheter or a plurality of catheters in a spatially-defined implantation within the tissue of a patient is provided. The system can include a tissue navigation system and a probe to inform the navigation system to guide emplacement of the catheters within a target tissue. The probe can provide images, such as fiberoptic visual images, or ultrasound images, or can provide radiolocation data, to guide the catheter emplacement. The catheters supply a pressurized liquid including a bioactive agent, such as can be used in the treatment of cancer, for example 123I- or 125I-IUDR. The system and methods provided can be used in the treatment of locally advanced tumors, such as cancers of the brain, head or neck, esophagus, prostate, ovary, liver, pancreas, bladder or rectum.
摘要翻译： 提供了一种导管系统，其适于在病人组织内的空间限定的植入物中导航，引导和植入导管或多个导管。 该系统可以包括组织导航系统和探针，以通知导航系统来引导导管在目标组织内的位置。 探针可以提供诸如光学视觉图像或超声图像的图像，或者可以提供无线电定位数据来引导导管放置。 导管提供包括生物活性剂的加压液体，例如可用于治疗癌症，例如123I-或125I-IUDR。 提供的系统和方法可用于局部晚期肿瘤的治疗，如脑，头颈部，食管，前列腺，卵巢，肝，胰腺，膀胱或直肠癌。
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公开(公告)号：US20100222668A1
公开(公告)日：2010-09-02
申请号：US12531808
申请日：2008-03-20
申请人： William D. Dalke , Kevin Lillehei , Thomas A. Jellison , Michael J. Gerber , James E. Matsuura , Stephen L. Warren
发明人： William D. Dalke , Kevin Lillehei , Thomas A. Jellison , Michael J. Gerber , James E. Matsuura , Stephen L. Warren
CPC分类号： A61K51/0491 , Y10T137/0402
摘要： A catheter system adapted for navigating, guiding and implanting a catheter or a plurality of catheters in a spatially-defined implantation within the tissue of a patient is provided. The system can include a tissue navigation system and a probe to inform the navigation system to guide emplacement of the catheters within a target tissue. The probe can provide images, such as fiberoptic visual images, or ultrasound images, or can provide radiolocation data, to guide the catheter emplacement. The catheters supply a pressurized liquid including a bioactive agent, such as can be used in the treatment of cancer, for example 123I- or 125I-IUDR. The system and methods provided can be used in the treatment of locally advanced tumors, such as cancers of the brain, head or neck, esophagus, prostate, ovary, liver, pancreas, bladder or rectum.
摘要翻译： 提供了一种导管系统，其适于在病人组织内的空间限定的植入物中导航，引导和植入导管或多个导管。 该系统可以包括组织导航系统和探针，以通知导航系统来引导导管在目标组织内的位置。 探针可以提供诸如光学视觉图像或超声图像的图像，或者可以提供无线电定位数据来引导导管放置。 导管提供包括生物活性剂的加压液体，例如可用于治疗癌症，例如123I-或125I-IUDR。 提供的系统和方法可用于局部晚期肿瘤的治疗，如脑，头颈部，食管，前列腺，卵巢，肝，胰腺，膀胱或直肠癌。
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公开(公告)号：US20110202074A1
公开(公告)日：2011-08-18
申请号：US12937154
申请日：2009-04-09
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0642 , A61B2017/00805 , A61B2017/0409 , A61B2017/0414 , A61B2017/0416 , A61B2017/0417 , A61B2017/0427 , A61B2017/0451 , A61B2017/06052 , A61B2017/06176
摘要： The invention relates to a medical suture (100) and devices and methods for deploying a medical suture. One embodiment of the invention relates to a suture deployment device (800) and method of use, wherein the suture deployment devices includes a housing (805), a substantially hollow elongate needle (600), a suture storage cartridge (700), a push rod (740) adapted to retractably extend through the hollow elongate needle, and a deployment mechanism (815) for retractably extending the push rod though the hollow elongate needle, wherein the push rod is adapted to eject a loaded suture from a distal end of the hollow elongate needle when extended.
摘要翻译： 本发明涉及医用缝合线（100）以及用于部署医用缝合线的装置和方法。 本发明的一个实施例涉及一种缝合线展开装置（800）和使用方法，其中所述缝合线展开装置包括壳体（805），基本上中空的细长针（600），缝线存储筒（700），推动 杆（740）适于可伸缩地延伸穿过中空细长针;以及展开机构（815），用于通过所述中空细长针可伸缩地延伸所述推杆，其中所述推杆适于从所述中空细长针的远端喷射加载的缝合线 中空细长针伸长时。
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公开(公告)号：US4772093A
公开(公告)日：1988-09-20
申请号：US917915
申请日：1986-10-10
CPC分类号： G02B23/26 , A61B1/00096 , A61B1/00101 , A61B1/0011 , A61B1/00165 , A61B1/00167 , Y10S600/92
摘要： An elongated image-carrying member that enables microendoscopy to be practiced using normal-sized catheters, includes a drawn, fused, central multi-fiber micro-unit of about 0.5 mm diameter, having about 2,000 glass fibers in coherent array, with a polymeric coating bonded to its pristine as-drawn outer surface. This combination achieves sufficient flexibility and optical qualities to enable effective use to provide vision for inspection of small passages and ducts. Flexible image-carrying members having diameter of 0.5 millimeter or less and catheters of diameter of 3 mm or less incorporating such members and effective working channels are achievable. For vision in remote areas, the micro-unit is employed with a substantially spherical lens with an ocular system for providing a focus range from less than about 2 mm to infinity and having resolution of detail down to the order of about 0.001 inch. The micro-optical member may be employed with a handpiece in a vision system, the micro-optical member being joined to the handpiece by a detachable connector having a stepped structure for precise alignment between the handle and the micro-optical member. By application of a relatively thin coating containing an opaque constituent to the as drawn micro-unit, degradation of the image and avoidance of artifacts caused by wave guiding effect are avoided. Devices with varying bend radiuses are also shown.
摘要翻译： 使用正常大小的导管实现微内窥镜检查的细长图像承载构件包括具有大约0.5mm直径的拉伸，熔化的中心多纤维微单元，具有约2000个相干阵列的玻璃纤维，聚合物涂层 粘合到其原始的外表面。 这种组合实现了足够的灵活性和光学质量，以有效地使用以提供小通道和管道检查的视觉。 直径为0.5毫米或更小的柔性图像承载构件和直径为3mm或更小的导管结合了这些构件和有效的工作通道是可以实现的。 对于远程区域的视觉，微单元采用具有眼睛系统的基本上球面的透镜，用于提供从小于约2mm到无穷远的聚焦范围，并且具有约0.001英寸量级的细节分辨率。 微型光学构件可以与视觉系统中的手持件一起使用，微型光学构件通过具有阶梯结构的可拆卸连接器与手持件接合，用于手柄和微型光学构件之间的精确对准。 通过将涂层中含有不透明成分的相对薄的涂层施加到如图所示的微单元上，避免了图像的劣化和避免由波导效应引起的伪影。 还显示了具有不同弯曲半径的设备。
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