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41 条记录 (耗时 0.021 秒)

    Methods and Apparatus for Treating Glaucoma
    2.
    发明申请
    Methods and Apparatus for Treating Glaucoma 有权
    治疗青光眼的方法和装置

    公开(公告)号：US20090227934A1

    公开(公告)日：2009-09-10

    申请号：US12398847

    申请日：2009-03-05

    申请人： Charles L. Euteneuer ,  Thomas R. Hektner ,  Andrew T. Schieber ,  John Wardle

    发明人： Charles L. Euteneuer ,  Thomas R. Hektner ,  Andrew T. Schieber ,  John Wardle

    IPC分类号： A61F9/007 ,  A61B17/32

    CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F2009/00885 ,  A61F2009/00891 ,  A61K9/0051 ,  A61M27/002 ,  A61M2210/0612 ,  Y10S623/905 ,  Y10S623/906

    摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

    摘要翻译： 提供了用于治疗青光眼的眼部植入物，其可以包括任何数量的特征。 更具体地说，本发明涉及有利于将流体从眼睛的一个区域转移到眼睛的另一区域的植入物。 植入物的一个特点是它包括适于插入眼睛前房的近端入口部分和远侧入口部分，以及适于插入施莱姆氏管的中间部分。 植入物的另一个特征是它可被偏置以呈现预定的形状以帮助放置在眼睛内。

    System and method of providing a blood-free interface for intravascular light delivery
    3.
    发明授权
    System and method of providing a blood-free interface for intravascular light delivery 失效
    为血管内光输送提供无血界面的系统和方法

    公开(公告)号：US5876426A

    公开(公告)日：1999-03-02

    申请号：US662585

    申请日：1996-06-13

    申请人： Stewart M. Kume ,  Thomas R. Hektner

    发明人： Stewart M. Kume ,  Thomas R. Hektner

    IPC分类号： A61B18/00 ,  A61B18/24 ,  A61M3/02 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/104 ,  A61B18/245 ,  A61B2018/0097 ,  A61M2025/105 ,  A61M2025/1072 ,  A61M3/0279

    摘要： A system and method of providing a blood-free interface for intravascular light delivery is disclosed. The method includes the steps of inserting a balloon catheter into the vasculature of a patient wherein the balloon catheter includes an infusion layer disposed about the balloon; inserting a light delivery catheter into the working lumen of the balloon catheter; inflating the balloon to displace blood inside the vasculature; infusing a liquid to displace blood between the inflated balloon and the inside wall of the vasculature so as to provide a relatively blood-free interface; and delivering light through the blood-free interface to the vasculature from the light delivery catheter. Fluid may be infused into the working lumen of the balloon catheter and around the light delivery catheter in order to displace any blood in the lumen. The system includes a light delivery catheter and a balloon catheter where the balloon catheter includes a long shaft having an inflation lumen, an infusion lumen and a working lumen. A balloon is connected to the distal end of the shaft and an infusion layer is disposed about the balloon. The catheter may include one or more radial restraints disposed about the balloon to center the working lumen and to limit the expandable diameter of the balloon. The radial restraint imparts flexibility and allows the balloon and the working lumen to be centered in vasculature that is curved (i.e., non-linear).

    摘要翻译： 公开了提供用于血管内光输送的无血界面的系统和方法。 该方法包括以下步骤：将气囊导管插入患者的脉管系统中，其中气囊导管包括围绕气囊设置的输注层; 将光输送导管插入到气囊导管的工作腔中; 充气气球以置换血管内的血液; 输注液体以置换充气气囊和脉管系统内壁之间的血液，以提供相对无血液的界面; 并将光通过无血清界面从光输送导管输送到脉管系统。 可以将流体输入气囊导管的工作腔和光输送导管周围，以便置换内腔中的任何血液。 该系统包括光输送导管和球囊导管，其中气囊导管包括具有充气腔，输液腔和工作腔的长轴。 气球连接到轴的远端，并且输注层围绕气球设置。 导管可以包括围绕气囊设置的一个或多个径向限制器，以使工作腔体居中并限制气囊的可扩张直径。 径向约束提供了灵活性，并允许气球和工作腔在弯曲（即非线性）的脉管系统中居中。

    Guide wire with swivel
    4.
    发明授权
    Guide wire with swivel 失效
    导丝与旋转

    公开(公告)号：US5247942A

    公开(公告)日：1993-09-28

    申请号：US864443

    申请日：1992-04-06

    申请人： Richard R. Prather ,  Thomas R. Hektner

    发明人： Richard R. Prather ,  Thomas R. Hektner

    IPC分类号： A61B17/22 ,  A61M25/01

    CPC分类号： A61M25/0905 ,  A61B2017/22072

    摘要： A guide wire, and methods of use thereof, comprising a main part, an extension part, and a connector. The connector connects the main part to the extension part such that the main part and the extension part can be rotated relative to each other.

    摘要翻译： 导丝及其使用方法，包括主要部分，延伸部分和连接器。 连接器将主要部分连接到延伸部分，使得主要部分和延伸部分可相对于彼此旋转。

    Catheter system for the delivery of a low volume bolus
    7.
    发明授权
    Catheter system for the delivery of a low volume bolus 有权
    用于输送低体积推注的导管系统

    公开(公告)号：US06764461B2

    公开(公告)日：2004-07-20

    申请号：US09138131

    申请日：1998-08-21

    申请人： Timothy J. Mickley ,  Thomas R. Hektner ,  Louis Ellis ,  Gary L. Hendrickson

    发明人： Timothy J. Mickley ,  Thomas R. Hektner ,  Louis Ellis ,  Gary L. Hendrickson

    IPC分类号： A61F1320

    CPC分类号： A61M25/104 ,  A61M5/00 ,  A61M29/02 ,  A61M2025/0057 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1086 ,  A61M2025/1093

    摘要： A catheter system includes a catheter having a proximal end, a distal end, and a lumen extending therein. An administering portion is disposed at the distal end of the catheter and is configured to administer a bolus of liquid in response to positive pressure in a distal portion of the lumen. The catheter system of the present invention has a dead space of less 0.32 cc and preferably less than 0.15 cc in which residual therapeutic agents remain after delivery. The present invention also includes a method of administering a liquid to a treatment site. The distal end of the catheter is transluminally positioned proximate the treatment site. The catheter is charged by placing a bolus of the liquid in the lumen A positive pressure is created to drive the bolus to the administering tip to express the bolus from the distal end of the catheter.

    摘要翻译： 导管系统包括具有近端，远端和在其中延伸的内腔的导管。 给药部分设置在导管的远端处，并且构造成响应于内腔的远端部分中的正压而施用大量液体。 本发明的导管系统具有小于0.32cc，优选小于0.15cc的死空间，其中残留的治疗剂在分娩后残留。 本发明还包括向处理部位施用液体的方法。 导管的远端位于治疗部位附近。 导管通过将大量液体放置在内腔中来进行充电。产生正压力以将推注驱动到施用尖端以从导管的远端表达推注。

    Intravascular radiation delivery system
    8.
    发明授权
    Intravascular radiation delivery system 失效
    血管内辐射输送系统

    公开(公告)号：US06582353B1

    公开(公告)日：2003-06-24

    申请号：US09618253

    申请日：2000-07-18

    申请人： Roger N. Hastings ,  Thomas R. Hektner ,  Stewart M. Kume

    发明人： Roger N. Hastings ,  Thomas R. Hektner ,  Stewart M. Kume

    IPC分类号： A61N500

    CPC分类号： A61M25/0127 ,  A61M25/1002 ,  A61M2025/0177 ,  A61M2025/1047 ,  A61M2025/105 ,  A61M2025/1095 ,  A61N5/1002 ,  A61N2005/1003

    摘要： An intravascular radiation delivery system including a catheter, a radiation source disposed in an open-ended lumen in the catheter and a closed-ended sheath surrounding the radiation source so as to prevent blood and other fluids from coming into contact with the radiation source. Preferably, the open-ended lumen is centered in the balloon for uniform radiation delivery. The catheter may include a blood perfusion lumen under the balloon or around the balloon. The open-ended lumen in the catheter may have a reduced diameter adjacent the distal end of the catheter to prevent the radiation source from exiting the lumen. Methods of using the radiation delivery system are also disclosed. An alternative method of delivering radiation to a treatment site inside the vasculature of a patient using a gas-filled balloon catheter and a radiation source disposed in the balloon catheter. The treatment site is exposed to radiation, preferably beta radiation, through the gas-filled balloon.

    摘要翻译： 一种血管内辐射传播系统，包括导管，设置在导管内的开放式腔内的辐射源和围绕辐射源的封闭护套，以防止血液和其它流体与辐射源接触。 优选地，开口腔在球囊中居中以使辐射均匀。 导管可以包括气囊下方或气球周围的血液灌注腔。 导管中的开口腔可以具有邻近导管远端的减小的直径，以防止辐射源离开内腔。 还公开了使用辐射递送系统的方法。使用设置在球囊导管中的充气球囊导管和辐射源将辐射递送到患者脉管系统内部的治疗部位的替代方法。 通过充气球囊将治疗部位暴露于辐射，优选β辐射。

    Method for intravascular radioactive treatment
    9.
    发明授权
    Method for intravascular radioactive treatment 失效
    血管内放射治疗方法

    公开(公告)号：US06422989B1

    公开(公告)日：2002-07-23

    申请号：US09434744

    申请日：1999-11-05

    申请人： Thomas R. Hektner

    发明人： Thomas R. Hektner

    IPC分类号： A61N500

    CPC分类号： A61N5/1002 ,  A61N2005/1008

    摘要： A device, system and method for delivering radiation to interior body sites, including stenosed blood vessel regions for the purpose of inhibiting restenosis after angioplasty. A string having a radioactive first region, a second region, and an intermediate region is disposed within or along an elongate shaft having a distal return member. The string intermediate portion is typically initially looped over the distal return member. The radioactive region is normally initially disposed within a radiation shielding vault or enclosure. The elongate shaft can be advanced within a vessel to the site to be treated, followed by pulling the string to advance the string radioactive region within the shaft to the treatment site. After exposure, the string can be retracted, placing the radioactive string region back within the vault. The string can be used and re-used without sterilization when used within catheter lumens not in fluid communication with bodily fluids.

    摘要翻译： 用于将辐射递送到内部身体部位（包括狭窄的血管区域）以用于在血管成形术后抑制再狭窄的装置，系统和方法。 具有放射性第一区域，第二区域和中间区域的串被布置在具有远端返回构件的细长轴内或沿其延伸。 弦中间部分通常最初环绕在远端返回构件上。 放射性区域通常最初设置在辐射屏蔽保险库或外壳内。 细长轴可以在容器内前进到待处理的位置，然后拉动绳子以将杆内的弦放射性区域推进到处理位置。 曝光后，弦可以缩回，将放射线区域放回保险库内。 当在不与体液流体连通的导管腔内使用时，可以使用并重新使用该串而不进行灭菌。