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1.发明授权Reagents, methods, and systems for detecting methicillin-resistant Staphylococcus 有权用于检测耐甲氧西林葡萄球菌的试剂，方法和系统公开(公告)号：US08735554B2
公开(公告)日：2014-05-27
申请号：US12991679
申请日：2009-05-07
IPC分类号： C07K16/12 , G01N33/569
CPC分类号： G01N33/56938 , C07K16/1271 , C07K2317/55 , C07K2317/92 , G01N2469/10
摘要： The present invention provides PBP2a peptide antigens for generating antibodies against MRSA, and provides high-affinity binding agents that detect MRSA by selective immunoreactivity with PBP2a. The antibodies are useful in methods and systems for detecting MRSA, including biosensor systems, or as components of diagnostic or detection kits. The antibodies, in some embodiments, have therapeutic value against MRSA infection.
摘要翻译： 本发明提供用于产生针对MRSA的抗体的PBP2a肽抗原，并提供通过与PBP2a的选择性免疫反应性检测MRSA的高亲和力结合剂。 抗体可用于检测MRSA的方法和系统，包括生物传感器系统，或诊断或检测试剂盒的组成部分。 在一些实施方案中，抗体具有抗MRSA感染的治疗价值。
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2.发明授权公开(公告)号：US07833758B2
公开(公告)日：2010-11-16
申请号：US11584253
申请日：2006-10-20
摘要： West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
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3.发明申请Identification of Oligonucleotides for the Capture, Detection and Quantitation of Hepatitis A Viral Nucleic Acid 审中-公开鉴定用于捕获，检测和定量甲型肝炎病毒核酸的寡核苷酸公开(公告)号：US20120219941A1
公开(公告)日：2012-08-30
申请号：US13301599
申请日：2011-11-21
CPC分类号： C12Q1/706 , C12Q1/703 , Y02A50/54 , C12Q2563/107 , C12Q2545/114 , C12Q2525/15 , C12Q2563/143
摘要： Hepatitis A virus-specific primers and probes derived from conserved regions of the hepatitis A virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
摘要翻译： 公开了甲型肝炎病毒特异性引物和衍生自甲型肝炎病毒基因组保守区域的探针。 还公开了使用捕获寡核苷酸，引物和探针的基于核酸的测定。
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4.发明授权Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus 失效鉴定用于西尼罗病毒捕获，检测和定量的寡核苷酸公开(公告)号：US07132233B2
公开(公告)日：2006-11-07
申请号：US10729421
申请日：2003-12-05
CPC分类号： C07K14/005 , C12N2770/24122 , C12Q1/701
摘要： West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
摘要翻译： 公开了西尼罗病毒捕获寡核苷酸，衍生自西尼罗河病毒基因组保守区域的引物和探针。 还公开了使用捕获寡核苷酸，引物和探针的基于核酸的测定。
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公开(公告)号：US06936442B2
公开(公告)日：2005-08-30
申请号：US10187253
申请日：2002-06-28
CPC分类号： C12Q1/701
摘要： Human parvovirus B19 primers and probes derived from conserved regions of the parvovirus B19 genome are disclosed. Also disclosed are nucleic acid-based assays using the primers and probes.
摘要翻译： 公开了衍生自细小病毒B19基因组的保守区的人细小病毒B19引物和探针。 还公开了使用引物和探针的基于核酸的测定法。
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6.发明申请公开(公告)号：US20120015345A1
公开(公告)日：2012-01-19
申请号：US13088273
申请日：2011-04-15
CPC分类号： C07K14/005 , C12N2770/24122 , C12Q1/701
摘要： West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
摘要翻译： 公开了西尼罗病毒捕获寡核苷酸，衍生自西尼罗河病毒基因组保守区域的引物和探针。 还公开了使用捕获寡核苷酸，引物和探针的基于核酸的测定。
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7.发明申请Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus 有权鉴定用于西尼罗病毒捕获，检测和定量的寡核苷酸公开(公告)号：US20070128637A1
公开(公告)日：2007-06-07
申请号：US11584252
申请日：2006-10-20
CPC分类号： C07K14/005 , C12N2770/24122 , C12Q1/701
摘要： West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
摘要翻译： 公开了西尼罗病毒捕获寡核苷酸，衍生自西尼罗河病毒基因组保守区域的引物和探针。 还公开了使用捕获寡核苷酸，引物和探针的基于核酸的测定。
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8.发明申请Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus 失效鉴定用于西尼罗病毒捕获，检测和定量的寡核苷酸公开(公告)号：US20050032729A1
公开(公告)日：2005-02-10
申请号：US10729421
申请日：2003-12-05
CPC分类号： C07K14/005 , C12N2770/24122 , C12Q1/701
摘要： West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
摘要翻译： 公开了西尼罗病毒捕获寡核苷酸，衍生自西尼罗河病毒基因组保守区域的引物和探针。 还公开了使用捕获寡核苷酸，引物和探针的基于核酸的测定。
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公开(公告)号：US07867731B2
公开(公告)日：2011-01-11
申请号：US10977087
申请日：2004-10-28
申请人： Christoph Reinhard , Anne Bennett Jefferson , Vivien W. Chan , Joerg Kaufmann , Hong Xin , Giulia C. Kennedy , Greg Harrowe , Hamiduddin Khoja , Venkatakrishna Shyamala
发明人： Christoph Reinhard , Anne Bennett Jefferson , Vivien W. Chan , Joerg Kaufmann , Hong Xin , Giulia C. Kennedy , Greg Harrowe , Hamiduddin Khoja , Venkatakrishna Shyamala
IPC分类号： C12P21/00 , C12P21/02 , C12N15/09 , C07K14/00 , C07K14/435
CPC分类号： G01N33/5005 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K2039/505 , C07K14/47 , C07K14/723 , C12N9/1205 , C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , C12Q2600/158 , C12Y207/01037 , G01N33/5008 , G01N33/5011 , G01N33/57415 , G01N33/57419 , G01N33/57496 , G01N33/68 , G01N33/6842 , G01N2500/00
摘要： The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
摘要翻译： 本发明提供在癌细胞中差异表达的多核苷酸以及由此编码的多肽。 这些多核苷酸可用于各种诊断和治疗方法。 本发明还提供减少癌细胞生长的方法。 这些方法可用于治疗癌症。
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10.发明授权Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus 有权鉴定用于西尼罗病毒捕获，检测和定量的寡核苷酸公开(公告)号：US07807813B2
公开(公告)日：2010-10-05
申请号：US11584252
申请日：2006-10-20
CPC分类号： C07K14/005 , C12N2770/24122 , C12Q1/701
摘要： West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
摘要翻译： 公开了西尼罗病毒捕获寡核苷酸，衍生自西尼罗河病毒基因组保守区域的引物和探针。 还公开了使用捕获寡核苷酸，引物和探针的基于核酸的测定。
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