公开(公告)号：US06174517B1

公开(公告)日：2001-01-16

申请号：US08975162

申请日：1997-11-20

Applicant: Isabelle Hansenne ,  Victoria Van Leeuwen

Inventor： Isabelle Hansenne ,  Victoria Van Leeuwen

IPC: A61K742

CPC classification number: B82Y5/00 ,  A61K8/0241 ,  A61K8/29 ,  A61K8/35 ,  A61K8/585 ,  A61K8/891 ,  A61K2800/413 ,  A61K2800/43 ,  A61K2800/624 ,  A61Q17/04

Abstract: The present invention relates to new cosmetic compositions for topical use which are intended more particularly for the photoprotection of the skin and/or hair against ultraviolet radiation and to their use in the abovementioned cosmetic application. Still more precisely, it relates to antisun compositions which comprise, in a cosmetically acceptable vehicle, an association of a specific screening agent, chosen from dibenzoylmethane derivatives, with at least one inorganic titanium oxide nanopigment treated with silanes and/or silicones.

Abstract translation: 本发明涉及用于局部用途的新型化妆品组合物，其更特别用于防紫外线辐射对皮肤和/或毛发的光保护及其在上述化妆品应用中的用途。 更准确地说，它涉及在化妆品可接受的载体中包含选自二苯甲酰甲烷衍生物的特定筛选剂与至少一种用硅烷和/或硅氧烷处理的无机氧化钛纳米颜料的缔合。

公开(公告)号：US5605679A

公开(公告)日：1997-02-25

申请号：US463762

申请日：1995-06-05

Applicant: Isabelle Hansenne ,  Victoria Van Leeuwen

Inventor： Isabelle Hansenne ,  Victoria Van Leeuwen

IPC: A61K8/19 ,  A61K20060101 ,  A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06 ,  A61K8/11 ,  A61K8/27 ,  A61K8/28 ,  A61K8/29 ,  A61K8/30 ,  A61K8/33 ,  A61K8/35 ,  A61K8/36 ,  A61K8/368 ,  A61K8/37 ,  A61K8/40 ,  A61K8/44 ,  A61K8/49 ,  A61K8/67 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61K9/113 ,  A61Q1/00 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q17/04 ,  C07C49/255 ,  C07C49/683 ,  C09K3/00 ,  A61K7/42 ,  A61K7/40

CPC classification number: A61Q17/04 ,  A61K8/35 ,  A61K8/40 ,  Y10S514/844 ,  Y10S514/938

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of 4-methylbenzylidenecamphor and, optionally, of 4-(tert-butyl)-4'-methoxydibenzoylmethane and (ii) a 2-ethylhexyl .alpha.-cyano-.beta.,.beta.-diphenylacrylate sunscreen solvent, in an amount sufficient to substantially completely dissolve the total amount of the sunscreen constituent (i), in a cosmetically acceptable vehicle, diluent or carrier therefor.

Abstract translation: 特别适用于对人体皮肤和/或头发进行增强光保护以抵抗UV-A和UV-B辐照（特别是太阳辐射）的破坏性影响的局部适用的防晒/化妆品组合物包括（i）光保护有效量的4-甲基亚苄基樟脑， 4-（叔丁基）-4'-甲氧基二苯甲酰甲烷和（ii）2-乙基己基α-氰基-β，β-二苯基丙烯酸酯防晒溶剂，其量足以基本上完​​全溶解防晒成分的总量 （i），在化妆品可接受的载体中，稀释剂或载体。

公开(公告)号：US07396526B1

公开(公告)日：2008-07-08

申请号：US09565716

申请日：2000-05-05

Applicant: Curtis A. Cole ,  Laura E. Flack ,  Claudia Kaminski ,  Victoria Van Leeuwen ,  Elvin R. Lukenbach

Inventor： Curtis A. Cole ,  Laura E. Flack ,  Claudia Kaminski ,  Victoria Van Leeuwen ,  Elvin R. Lukenbach

IPC: A61K31/74 ,  A61K9/00 ,  A61K8/02

CPC classification number: A61K8/365 ,  A61K8/368 ,  A61K8/671 ,  A61Q19/00 ,  A61Q19/08

Abstract: There are provided compositions which include a retinoid and preferably retinal; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinal; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.

Abstract translation: 提供了包含类视黄醇并优选视黄醛的组合物; 皮肤病学活性的酸; 和挥发性碱，例如氢氧化铵。 本发明的另一个实施方案包括包含类视黄醇并优选视黄醛的组合物; 皮肤病学活性的酸; 挥发性碱 和第二中和剂。 还提供了组合物，其包含类视黄醇，皮肤病学活性酸的中和铵盐，以及任选的除铵盐之外的中和盐。 还提供了减少有需要的哺乳动物的细纹，皱纹，皮肤粗糙度和孔径以及增加皮肤表面的清晰度，细胞周转，皮肤光泽，皮肤光滑度，皮肤渗透或胶原蛋白合成的方法。 如上所述的组合物局部施用于动物的皮肤。

公开(公告)号：US20050019284A1

公开(公告)日：2005-01-27

申请号：US10486096

申请日：2002-08-14

Applicant: Victoria Van Leeuwen ,  Marie-Paule Robert ,  Patricia Manissier

Inventor： Victoria Van Leeuwen ,  Marie-Paule Robert ,  Patricia Manissier

IPC: A61K8/19 ,  A61K8/29 ,  A61K8/67 ,  A61Q1/02 ,  A61Q17/04 ,  A61K7/021

CPC classification number: A61Q17/04 ,  A61K8/19 ,  A61K8/29 ,  A61K8/671 ,  A61Q1/02

Abstract: The present invention relates to cosmetic compositions having good physical and chemical stability, comprising a retinoid and at least one coloured pigment selected from metal oxides, the said pigments being treated (or coated) with one or more hydrophilic or lipophilic components.

Abstract translation: 本发明涉及具有良好物理和化学稳定性的化妆品组合物，其包含类视黄醇和至少一种选自金属氧化物的着色颜料，所述颜料用一种或多种亲水或亲脂性组分进行处理（或涂覆）。

公开(公告)号：US06544531B1

公开(公告)日：2003-04-08

申请号：US09436867

申请日：1999-11-09

Applicant: Curtis A. Cole ,  Laura E. Flack ,  Claudia Kaminski ,  Victoria Van Leeuwen

Inventor： Curtis A. Cole ,  Laura E. Flack ,  Claudia Kaminski ,  Victoria Van Leeuwen

IPC: A61K600

CPC classification number: A61Q19/00 ,  A61K8/365 ,  A61K8/368 ,  A61K8/671 ,  A61Q19/08 ,  Y10S977/926

Abstract: There are provided compositions which include a retinoid and preferably retinol; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinol; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.

Abstract translation: 提供了包含类视色素并且优选视黄醇的组合物; 皮肤病学活性的酸; 和挥发性碱，例如氢氧化铵。 本发明的另一个实施方案包括含有类视黄醇并优选视黄醇的组合物; 皮肤病学活性的酸; 挥发性碱 和第二中和剂。 还提供了组合物，其包含类视黄醇，皮肤病学活性酸的中和铵盐，以及任选的除铵盐之外的中和盐。 还提供了减少有需要的哺乳动物的细纹，皱纹，皮肤粗糙度和孔径以及增加皮肤表面的清晰度，细胞周转，皮肤光泽，皮肤光滑度，皮肤渗透或胶原蛋白合成的方法。 如上所述的组合物局部施用于动物的皮肤。

公开(公告)号：US5667765A

公开(公告)日：1997-09-16

申请号：US461015

申请日：1995-06-05

Applicant: Isabelle Hansenne ,  Victoria van Leeuwen

Inventor： Isabelle Hansenne ,  Victoria van Leeuwen

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06 ,  A61K8/11 ,  A61K8/19 ,  A61K8/29 ,  A61K8/33 ,  A61K8/35 ,  A61K8/368 ,  A61K8/37 ,  A61K8/41 ,  A61K8/49 ,  A61K8/72 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61K31/60 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/04 ,  C07C49/215 ,  C07C49/437 ,  C09K3/00 ,  A61K7/42

CPC classification number: A61Q17/04 ,  A61K8/35 ,  A61K8/368 ,  A61K2800/59

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one of the sunscreen compounds 4-methylbenzylidenecamphor and/or 4-(tert-butyl)-4'-methoxydibenzoylmethane and (ii) at least one homomenthyl and/or octyl salicylate sunscreen solvent, in an amount sufficient to substantially completely dissolve the total amount of the at least one sunscreen compound (i), in a cosmetically acceptable vehicle, diluent or carrier therefore.

Abstract translation: 特别适用于对UV-A和UV-B照射，特别是太阳辐射的破坏性影响的人皮肤和/或头发的增强光保护的局部适用的防晒/美容组合物包括（i）光保护有效量的至少一种 防晒化合物4-甲基亚苄基樟脑和/或4-（叔丁基）-4'-甲氧基二苯甲酰甲烷和（ii）至少一种水杨酸甲酯和/或辛基水杨酸盐​​防晒溶剂，其量足以基本上完​​全溶解at 至少一种防晒化合物（i），因此在化妆品可接受的载体，稀释剂或载体中。

公开(公告)号：US6096294A

公开(公告)日：2000-08-01

申请号：US775624

申请日：1997-01-02

Applicant: Isabelle Hansenne ,  Victoria Van Leeuwen

Inventor： Isabelle Hansenne ,  Victoria Van Leeuwen

IPC: C07D251/70 ,  A61K8/00 ,  A61K8/04 ,  A61K8/19 ,  A61K8/27 ,  A61K8/28 ,  A61K8/29 ,  A61K8/30 ,  A61K8/33 ,  A61K8/35 ,  A61K8/368 ,  A61K8/37 ,  A61K8/41 ,  A61K8/49 ,  A61K8/67 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/04 ,  A61Q19/00 ,  C09K3/00 ,  A61K7/42 ,  A61K7/40

CPC classification number: A61K8/368 ,  A61K8/4966 ,  A61Q17/04 ,  Y10S514/844 ,  Y10S514/938

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and (ii) at least one homomenthyl and/or octyl salicylate solvent for the triazine sunscreen compound (i), in a cosmetically acceptable vehicle, diluent or carrier therefor.

Abstract translation: 特别适用于对人体皮肤和/或头发的增强光保护的UV-A和UV-B照射，特别是太阳辐射的破坏性影响的局部适用防晒/化妆品组合物包括（i）光保护有效量的2,4,6 - 三（[（2'-乙基己基）氧羰基）苯胺基] -1,3,5-三嗪和（ii）三美制防晒化合物（i）的至少一种高分子和/或辛基水杨酸酯溶剂， 可接受的车辆，稀释剂或载体。