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    FUNCTIONALIZED NANOMATERIALS FOR CHELATION THERAPIES AND SORBENT DIALYSIS OF TOXINS
    2.
    发明申请
    FUNCTIONALIZED NANOMATERIALS FOR CHELATION THERAPIES AND SORBENT DIALYSIS OF TOXINS 审中-公开
    用于治疗和功能性氧化还原毒素的纳米材料

    公开(公告)号：US20110110985A1

    公开(公告)日：2011-05-12

    申请号：US12613998

    申请日：2009-11-06

    申请人： Glen E. Fryxell ,  Charles Timchalk ,  Raymond S. Addleman ,  Wassana Yantasee

    发明人： Glen E. Fryxell ,  Charles Timchalk ,  Raymond S. Addleman ,  Wassana Yantasee

    IPC分类号： A61K9/00 ,  A61K33/00 ,  A61P39/04

    CPC分类号： G21F9/002 ,  G21F9/12 ,  G21F9/162

    摘要： A therapy agent is disclosed that is made up of a functionalized nanomaterial that provides solutions to current problems facing the field of chelation therapies and dialysis of metals, radionuclides, and metabolic wastes. Through the coupling of groups tailored to selectively capture specific toxins and rigid porous backbone structures (e.g., mesoporous silica and mesoporous carbon), suitable materials that are highly effective and fast at capturing toxins (metals, radionuclides, and metabolic wastes) in the presence of competing ions and proteins. These materials may be embodied in a variety of treatment devices which allow for treatment and removal of these target materials through a variety of methodologies including oral, dermal and dialysis pathways.

    摘要翻译： 公开了一种治疗剂，其由功能化的纳米材料制成，其为解决螯合治疗领域的当前问题和金属，放射性核素和代谢废物的透析提供了解决方案。 通过适合选择性捕获特定毒素和刚性多孔骨架结构（例如介孔二氧化硅和介孔碳）的组的耦合，在存在下存在毒素（金属，放射性核素和代谢废物）的情况下，高效有效捕获毒素的合适材料 竞争离子和蛋白质。 这些材料可以体现在各种治疗装置中，这些治疗装置允许通过包括口服，皮肤和透析途径的各种方法来处理和去除这些靶材料。

    Electrochemical Sensor and Methods for Making and Using Same
    4.
    发明申请
    Electrochemical Sensor and Methods for Making and Using Same 审中-公开
    电化学传感器及其使用方法

    公开(公告)号：US20090288962A1

    公开(公告)日：2009-11-26

    申请号：US12427431

    申请日：2009-04-21

    申请人： Wassana Yantasee ,  Glen E. Fryxell ,  Raymond S. Addleman ,  Yuehe Lin ,  Charles Timchalk

    发明人： Wassana Yantasee ,  Glen E. Fryxell ,  Raymond S. Addleman ,  Yuehe Lin ,  Charles Timchalk

    IPC分类号： G01N27/30 ,  B05D5/12 ,  G01N27/26

    CPC分类号： G01N27/42 ,  G01N33/1813 ,  G01N33/493 ,  G01N2610/00

    摘要： A mercury-free, electrochemical sensor is described that includes a self-assembled monolayer on a mesoporous support (SAMMS) composite and a fluoropolymer component that is deposited on a measurement surface. The SAMMS component provides outstanding metal preconcentration. The fluoropolymer component acts as an antifouling binder. The sensor can detect various metals at a low detection level in the presence of fouling agents and without sample pretreatment. The sensor is also able to detect mixtures of metals simultaneously with excellent single and inter-electrode reproducibility. Service lifetimes are excellent.

    摘要翻译： 描述了一种无汞电化学传感器，其包括介孔载体（SAMMS）复合材料上的自组装单层和沉积在测量表面上的含氟聚合物组分。 SAMMS组件提供卓越的金属预浓缩。 氟聚合物组分用作防污粘合剂。 传感器可以在存在污染物的情况下检测低检测水平的各种金属，并且无需样品预处理。 传感器还能够同时检测金属的混合物，具有优异的单电极和电极间再现性。 使用寿命很好。

    Carbon nanotube nanoelectrode arrays
    5.
    发明授权
    Carbon nanotube nanoelectrode arrays 失效
    碳纳米管纳米电极阵列

    公开(公告)号：US07452452B2

    公开(公告)日：2008-11-18

    申请号：US11017480

    申请日：2004-12-20

    申请人： Zhifeng Ren ,  Yuehe Lin ,  Wassana Yantasee ,  Guodong Liu ,  Fang Lu ,  Yi Tu

    发明人： Zhifeng Ren ,  Yuehe Lin ,  Wassana Yantasee ,  Guodong Liu ,  Fang Lu ,  Yi Tu

    IPC分类号： G01N27/30 ,  G01N27/327

    CPC分类号： B82Y30/00 ,  B82Y10/00 ,  B82Y40/00 ,  C01B32/162 ,  C01B2202/08 ,  C01B2202/34 ,  C01B2202/36 ,  D01F9/1271 ,  D01F9/1272 ,  D01F9/1275 ,  D01F9/1276 ,  H01L51/0048 ,  H01L51/0052 ,  Y10S977/747 ,  Y10S977/92 ,  Y10S977/957

    摘要： The present invention relates to microelectode arrays (MEAs), and more particularly to carbon nanotube nanoelectrode arrays (CNT-NEAs) for chemical and biological sensing, and methods of use. A nanoelectrode array includes a carbon nanotube material comprising an array of substantially linear carbon nanotubes each having a proximal end and a distal end, the proximal end of the carbon nanotubes are attached to a catalyst substrate material so as to form the array with a pre-determined site density, wherein the carbon nanotubes are aligned with respect to one another within the array; an electrically insulating layer on the surface of the carbon nanotube material, whereby the distal end of the carbon nanotubes extend beyond the electrically insulating layer; a second adhesive electrically insulating layer on the surface of the electrically insulating layer, whereby the distal end of the carbon nanotubes extend beyond the second adhesive electrically insulating layer; and a metal wire attached to the catalyst substrate material.

    摘要翻译： 本发明涉及微电极阵列（MEA），更具体地涉及用于化学和生物学感测的碳纳米管纳米电极阵列（CNT-NEAs）和使用方法。 纳米电极阵列包括碳纳米管材料，其包括各自具有近端和远端的基本上线性的碳纳米管阵列，碳纳米管的近端附着到催化剂衬底材料上， 确定的位置密度，其中所述碳纳米管在所述阵列内相对于彼此对准; 在碳纳米管材料的表面上的电绝缘层，由此碳纳米管的远端延伸超过电绝缘层; 在所述电绝缘层的表面上的第二粘合电绝缘层，由此所述碳纳米管的远端延伸超过所述第二粘合电绝缘层; 以及连接到催化剂基板材料的金属线。

    Carbon nanotube nanoelectrode arrays
    6.
    发明申请
    Carbon nanotube nanoelectrode arrays 失效
    碳纳米管纳米电极阵列

    公开(公告)号：US20050230270A1

    公开(公告)日：2005-10-20

    申请号：US11017480

    申请日：2004-12-20

    申请人： Zhifeng Ren ,  Yuehe Lin ,  Wassana Yantasee ,  Guodong Liu ,  Fang Lu

    发明人： Zhifeng Ren ,  Yuehe Lin ,  Wassana Yantasee ,  Guodong Liu ,  Fang Lu

    IPC分类号： C01B31/02 ,  D01F9/127 ,  H01L51/00 ,  H01L51/30 ,  G01N27/26

    CPC分类号： B82Y30/00 ,  B82Y10/00 ,  B82Y40/00 ,  C01B32/162 ,  C01B2202/08 ,  C01B2202/34 ,  C01B2202/36 ,  D01F9/1271 ,  D01F9/1272 ,  D01F9/1275 ,  D01F9/1276 ,  H01L51/0048 ,  H01L51/0052 ,  Y10S977/747 ,  Y10S977/92 ,  Y10S977/957

    摘要： The present invention relates to microelectode arrays (MEAs), and more particularly to carbon nanotube nanoelectrode arrays (CNT-NEAs) for chemical and biological sensing, and methods of use. A nanoelectrode array includes a carbon nanotube material comprising an array of substantially linear carbon nanotubes each having a proximal end and a distal end, the proximal end of the carbon nanotubes are attached to a catalyst substrate material so as to form the array with a pre-determined site density, wherein the carbon nanotubes are aligned with respect to one another within the array; an electrically insulating layer on the surface of the carbon nanotube material, whereby the distal end of the carbon nanotubes extend beyond the electrically insulating layer; a second adhesive electrically insulating layer on the surface of the electrically insulating layer, whereby the distal end of the carbon nanotubes extend beyond the second adhesive electrically insulating layer; and a metal wire attached to the catalyst substrate material.

    摘要翻译： 本发明涉及微电极阵列（MEA），更具体地涉及用于化学和生物学感测的碳纳米管纳米电极阵列（CNT-NEAs）和使用方法。 纳米电极阵列包括碳纳米管材料，其包括各自具有近端和远端的基本上线性的碳纳米管阵列，碳纳米管的近端附着到催化剂衬底材料上， 确定的位置密度，其中所述碳纳米管在所述阵列内相对于彼此对准; 在碳纳米管材料的表面上的电绝缘层，由此碳纳米管的远端延伸超过电绝缘层; 在所述电绝缘层的表面上的第二粘合电绝缘层，由此所述碳纳米管的远端延伸超过所述第二粘合电绝缘层; 以及连接到催化剂基板材料的金属线。