公开(公告)号：US08377482B2

公开(公告)日：2013-02-19

申请号：US11574692

申请日：2005-09-07

Applicant: Robert N. Laurie ,  William A. Smith

Inventor： Robert N. Laurie ,  William A. Smith

IPC: A61K33/00 ,  A61K33/04 ,  A61K33/18 ,  A61K33/24 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K31/194 ,  A61K31/28 ,  A61K31/295 ,  A61K31/30

CPC classification number: A61K33/34 ,  A61K9/0019 ,  A61K9/08 ,  A61K31/00 ,  A61K33/00 ,  A61K33/04 ,  A61K33/18 ,  A61K33/24 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K45/06 ,  A61K47/10 ,  A61K47/183 ,  A61K2300/00

Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.

Abstract translation: 本发明公开了一种微量元素溶液，其包含选自硒，铜，锌，锰和铬的至少一种金属; 和选自维生素，疫苗，生长兴奋剂，驱虫剂，葡聚糖铁，抗生素和同步制剂的组中的至少一种成分。 同步准备是可注射的激素制剂，可植入激素制剂，阴道内激素制剂和其他缓释激素制剂的组合。 抗生素包括口服，可注射和可植入的治疗药物。 疫苗包括抗原和抗原和佐剂的组​​合。 生长兴奋剂包括溶奶油，雌二醇，睾丸激素，孕激素和醋酸奈特隆。 驱虫剂包括大分子内酯，leramizoles，苯并咪唑和水杨酰苯胺。 大分子内酯包括多拉菌素，伊维菌素，阿维菌素和莫昔克丁。

公开(公告)号：US20130013085A1

公开(公告)日：2013-01-10

申请号：US13464170

申请日：2012-05-04

Applicant: William A. Smith ,  Sergey Samorezov ,  Brian L. Davis ,  Antonie J. vanden Bogert

Inventor： William A. Smith ,  Sergey Samorezov ,  Brian L. Davis ,  Antonie J. vanden Bogert

IPC: A61F2/74

CPC classification number: A61F2/64 ,  A61F2/68 ,  A61F2002/5006 ,  A61F2002/701 ,  A61F2002/704 ,  A61F2002/74 ,  A61F2002/744 ,  A61F2002/748

Abstract: An energy-storing prosthetic knee includes an upper leg structure and a lower leg structure hingedly connected to the upper leg structure. The lower and upper leg structures move pivotally relative to one another. A fluid actuator is operatively connected to the upper and lower leg structures such that relative pivotal movement of the upper and lower leg structures causes a fluid to flow in a predetermined manner within the fluid actuator. At least two controllable variable fluid flow resisting devices, an accumulator, and a control system are also provided. The control system is actuable to cause storage of the fluid energy for a predetermined length of time and release of the fluid energy at a predetermined time during the gait cycle. Both the storage and release of the fluid energy are variable by action of the control system without physical modification of other components of the prosthetic knee.

Abstract translation: 储能假肢膝盖包括与腿部结构铰接地连接的上腿结构和小腿结构。 下腿和上腿结构相对于彼此枢转地运动。 流体致动器可操作地连接到上部和下部腿部结构，使得上部和下部腿部结构的相对枢转运动导致流体以预定的方式在流体致动器内流动。 还提供了至少两个可控流量可变阻流装置，蓄能器和控制系统。 控制系统可致动以在步态循环期间在预定时间内使流体能量存储预定长度的时间和释放流体能量。 液体能量的储存和释放都可以通过控制系统的作用而变化，而不会对假肢膝盖的其他部件进行物理修改。

公开(公告)号：US07435059B2

公开(公告)日：2008-10-14

申请号：US10378444

申请日：2003-03-03

Applicant: William A. Smith ,  Leonard A. R. Golding

Inventor： William A. Smith ,  Leonard A. R. Golding

IPC: F04B49/00

CPC classification number: A61M1/1031 ,  A61M1/101 ,  A61M1/1036 ,  A61M1/1075 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/3334 ,  A61M2205/8243

Abstract: A system for pumping blood to assist or assume the cardiac function of a patient is characterized by a blood pump that exhibits a steep performance curve such that only small changes in pump flow occur for large changes in differential pressure across the pump. The pump therefore exhibits flow-limiting characteristics to protect the physiological system against harmful flow rates or pressures. Pump flow may also be limited by controlling the current provided to a driver from a power supply or by suitable restrictions within or external to the pump housing.

Abstract translation: 用于抽吸血液以辅助或承担患者心脏功能的系统的特征在于具有陡峭性能曲线的血泵，使得只有小的泵浦流量的变化才能发生，因为泵的差压的大的变化。 因此，泵具有流动限制特性，以保护生理系统免受有害的流速或压力。 泵流量还可以通过控制从电源提供给驾驶员的电流或通过在泵壳体内部或外部的适当限制来限制。

公开(公告)号：US20080102074A1

公开(公告)日：2008-05-01

申请号：US11574692

申请日：2005-09-07

Applicant: Robert N. Laurie ,  William A. Smith

Inventor： Robert N. Laurie ,  William A. Smith

IPC: A61K33/32 ,  A61K33/34 ,  A61K39/00 ,  A61P43/00

CPC classification number: A61K33/34 ,  A61K9/0019 ,  A61K9/08 ,  A61K31/00 ,  A61K33/00 ,  A61K33/04 ,  A61K33/18 ,  A61K33/24 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K45/06 ,  A61K47/10 ,  A61K47/183 ,  A61K2300/00

Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronisation preparation. The synchronisation preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.

Abstract translation: 本发明公开了一种微量元素溶液，其包含选自硒，铜，锌，锰和铬的至少一种金属; 和选自维生素，疫苗，生长兴奋剂，驱虫剂，葡聚糖铁，抗生素和同步制剂的组中的至少一种成分。 同步准备是可注射的激素制剂，可植入激素制剂，阴道内激素制剂和其他缓释激素制剂的组合。 抗生素包括口服，可注射和可植入的治疗药物。 疫苗包括抗原和抗原和佐剂的组​​合。 生长兴奋剂包括溶奶油，雌二醇，睾丸激素，孕激素和醋酸奈特隆。 驱虫剂包括大分子内酯，leramizoles，苯并咪唑和水杨酰苯胺。 大分子内酯包括多拉菌素，伊维菌素，阿维菌素和莫昔克丁。

公开(公告)号：US07189260B2

公开(公告)日：2007-03-13

申请号：US10333760

申请日：2001-03-19

Applicant: David Horvath ,  Leonard A. R. Golding ,  William A. Smith

Inventor： David Horvath ,  Leonard A. R. Golding ,  William A. Smith

IPC: A61M1/10

CPC classification number: F04D29/2211 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/122 ,  A61M1/127 ,  F04D13/0646

Abstract: In a centrifugal flow blood pump, usable in left ventricular assist applications, blood is pumped from an inlet (16) to an outlet (22) by a primary impeller (18). A portion of the blood that enters the pump follows a secondary channel (24) where a secondary impeller (70) routes the blood to lubricate a bearing between an impeller assembly (14) and a post formed by a component of the pump housing. The unique shape of the secondary impeller (70) prevents blood stagnation and provides for a well-washed fluid bearing.

Abstract translation: 在可用于左心室辅助应用的离心流血泵中，血液通过主叶轮（18）从入口（16）泵送到出口（22）。 进入泵的一部分血液遵循辅助通道（24），其中次级叶轮（70）引导血液以润滑叶轮组件（14）和由泵壳体的部件形成的柱之间的轴承。 二次叶轮（70）的独特形状防止血液滞留，并提供良好洗涤的流体轴承。

公开(公告)号：USD437620S1

公开(公告)日：2001-02-13

申请号：US29111055

申请日：1999-09-17

Applicant: William A. Smith ,  Nicholas L. Voden

Designer： William A. Smith ,  Nicholas L. Voden

公开(公告)号：US6010467A

公开(公告)日：2000-01-04

申请号：US916513

申请日：1997-08-22

Applicant: William A. Smith

Inventor： William A. Smith

IPC: A61H39/00 ,  A61H39/02 ,  A61N1/34 ,  A61H39/04 ,  A61N1/32

CPC classification number: A61N1/36021 ,  A61H39/002 ,  A61H39/02 ,  A61H2205/081

Abstract: An apparatus for enabling the patient himself or herself to engage the skin on his or her back to locate and treat trigger points thereunder, using a source of pulsed voltage. The apparatus includes a wand having a generally rigid and electrically-conductive arcuate handle of about an arm's length or less in length, a spade-shaped electrically-conductive extension with a free end formed with tapering straight edges merging in a rounded point and welded on its other end to the handle, and a cable secured on the other end of the handle to connect to connect the extension electrically to the source of pulsed voltage. A somewhat comparably-shaped sponge is fixed to the extension. A grip at the other end of the handle facilitates moving the wand so that a tapering straight edge and/or the rounded point of the spade-shaped extension glides over the back's skin when searching for trigger points, and for holding the rounded point there when a trigger point is located to enable precise electrically stimulation of the tissue near the trigger point.

Abstract translation: 一种用于使患者本人能够使用其脉冲电压源将皮肤贴靠在他或她的背部来定位和治疗其下的触发点的装置。 该装置包括具有大致刚性且导电的弓形手柄，其长度大约为臂长度或较短长度的锹状导电延伸部，其自由端形成有锥形直边并入圆形点并焊接在 另一端固定在手柄上，以及固定在手柄另一端上的电缆，用于将延长部分电连接到脉冲电压源。 一个稍微相对形状的海绵固定在延伸部上。 手柄另一端的把手有助于移动杖，使得当搜索触发点时，铲形延伸部的锥形直边缘和/或圆形点在背部皮肤上滑动，并且用于将圆角保持在那里， 触发点被定位成能够精确地电刺激触发点附近的组织。

公开(公告)号：US5890883A

公开(公告)日：1999-04-06

申请号：US820756

申请日：1997-03-19

Applicant: Leonard A. R. Golding ,  William A. Smith

Inventor： Leonard A. R. Golding ,  William A. Smith

IPC: F04D29/046 ,  A61M1/10 ,  F04D29/04 ,  F04D29/047 ,  F04B35/04

CPC classification number: F04D29/047 ,  A61M1/1017

Abstract: A blood pump incorporates a blood lubricated journal bearing that is characterized by a non-circular geometry. In one embodiment, the stationary bearing element, or stator, of the bearing is provided with a semi-elliptical shaped outer surface in an area opposite the load bearing film. The journal bearing configuration ensures that the blood flow therethrough is adequate, that the integrity of the blood is preserved and that bearing stability is maintained.

Abstract translation: 血泵结合了血液润滑的轴颈轴承，其特征在于非圆形几何形状。 在一个实施例中，轴承的固定轴承元件或定子在与承载膜相对的区域中设置有半椭圆形的外表面。 轴颈配置确保通过其中的血液流动充分，保持血液的完整性并保持轴承的稳定性。

公开(公告)号：US5595154A

公开(公告)日：1997-01-21

申请号：US387602

申请日：1995-02-13

Applicant: William A. Smith

Inventor： William A. Smith

IPC: F01C1/20 ,  F01C1/28 ,  F02B53/00

CPC classification number: F01C1/20 ,  F01C1/28 ,  F02B53/00

Abstract: A rotary engine is provided with a rotary piston that is rotatively mounted within a housing. The rotary piston includes a surrounding circumferential edge that is provided with a series of distinct depressions formed therein. Formed in the housing outwardly of the rotary piston is a pair of valve housings with each valve housing including a rotary valve mounted therein. Each of the rotary valves are driven in time relationship to the rotary piston. As the rotary piston rotates within the housing, there is a series of chambers defined between respective depressions and the housing. Moreover, as the rotary piston and rotary valves rotate, they cooperate to form four separate chambers around the rotary piston, including combustion, exhaust, intake, and compression chambers. In the embodiment illustrated herein, for each revolution of the rotary piston, there are two compression, intake, exhaust and combustion cycles or phases.

Abstract translation: 旋转发动机设置有旋转活塞，其旋转地安装在壳体内。 旋转活塞包括周围的圆周边缘，其中形成有一系列明显的凹陷。 在旋转活塞外部的壳体中形成有一对阀壳体，每个阀壳体包括安装在其中的旋转阀。 每个旋转阀与旋转活塞的时间关系被驱动。 当旋转活塞在壳体内旋转时，存在限定在相应凹部和壳体之间的一系列腔室。 此外，当旋转活塞和旋转阀旋转时，它们协作以围绕旋转活塞（包括燃烧，排气，进气和压缩室）形成四个独立的室。 在本文所示的实施例中，对于旋转活塞的每次旋转，存在两个压缩，进气，排气和燃烧循环或相。

公开(公告)号：US5464505A

公开(公告)日：1995-11-07

申请号：US251158

申请日：1994-05-31

Applicant: Michael W. Peters ,  William A. Smith ,  Mark A. Mueller ,  William K. Culbreth, III

Inventor： Michael W. Peters ,  William A. Smith ,  Mark A. Mueller ,  William K. Culbreth, III

IPC: B01D3/40 ,  C07D301/32 ,  C07D303/04

CPC classification number: C07D301/32 ,  B01D3/40

Abstract: Propylene oxide adducts of oxyethylene glycols are used as extractive distillation agents in an extractive distillation column in the distillation of propylene oxide contaminated with water, acetone and methanol to obtain an overhead propylene oxide distillate fraction contaminated with reduced quantities of water, acetone and methanol, and a heavier bottoms distillation fraction containing substantially all of the extractive distillation agent, and acetone and some of the methanol and water introduced into the distillation column.

Abstract translation: 氧化乙烯二醇的环氧丙烷加成物在萃取蒸馏塔中用于在被水，丙酮和甲醇污染的环氧丙烷的蒸馏中用作萃取蒸馏剂，以获得被减少量的水，丙酮和甲醇污染的顶部环氧丙烷馏分，以及 含有基本上所有萃取蒸馏剂的较重的塔底蒸馏馏分，以及引入蒸馏塔中的丙酮和一些甲醇和水。