公开(公告)号：US20070217163A1

公开(公告)日：2007-09-20

申请号：US11376616

申请日：2006-03-15

Applicant: Wilson Greatbatch ,  Jeffrey Deal

Inventor： Wilson Greatbatch ,  Jeffrey Deal

IPC: H05K7/20

CPC classification number: A61N1/375 ,  A61N1/37211 ,  A61N1/3787

Abstract: An implantable device includes a device case comprising amorphous non-ferrous metal alloy material and having lower electrical conductivity than crystalline atomic structures comprising the same alloy constituents. The generation of eddy currents is thereby reduced and inductive charging and/or telemetry system operation can take place at higher frequencies with a resulting improvement in energy and data transfer efficiency.

Abstract translation: 可植入装置包括包含无定形有色金属合金材料并且具有比包含相同合金成分的结晶原子结构更低导电性的装置壳体。 从而降低了涡流的产生，并且可以在较高频率下进行感应充电和/或遥测系统操作，从而提高了能量和数据传输效率。

公开(公告)号：US07136701B2

公开(公告)日：2006-11-14

申请号：US10727349

申请日：2003-12-03

Applicant: Wilson Greatbatch ,  Jeffrey Deal

Inventor： Wilson Greatbatch ,  Jeffrey Deal

IPC: A61N1/40

CPC classification number: H01M16/00 ,  A61N1/08 ,  A61N1/378 ,  H01M6/16 ,  H01M6/5016 ,  H01M6/5033 ,  H01M10/052 ,  H01M10/0525 ,  H02J7/0054

Abstract: A hybrid battery power source for implantable medical use provides a generally constant low internal resistance during discharge and avoids voltage delays of the type that develop as a result of run down-induced resistance increase in Li/SVO cells. The hybrid battery power source utilizes two batteries or cells, one being a primary cell of relatively high energy density and the other being a secondary cell of relatively low internal resistance that is rechargeable. The primary and secondary cells are connected in a parallel arrangement via a voltage boost/charge control circuit that is powered by the primary cell and adapted to charge the secondary cell while limiting charge/discharge excursions thereof in a manner that optimizes its output for high energy medical device use. The energy storage capacitors of the medical device in which the hybrid battery power source is situated are driven by the secondary cell. The primary cell is used to as an energy source for recharging the secondary cell.

Abstract translation: 用于可植入医疗用途的混合电池电源在放电期间提供通常恒定的低内部电阻，并且避免由于Li / SVO电池的下降引起的电阻增加而发展的类型的电压延迟。 混合电池电源使用两个电池或电池，一个是相对较高能量密度的主电池，另一个是可再充电的内阻相对较低的二次电池。 主电池和次电池通过电压升压/充电控制电路以并联装置连接，该电压升压/充电控制电路由主电池供电并且适于对二次电池充电，同时以优化其高能量输出的方式限制充电/放电偏移 医疗器械使用。 混合电池电源所在的医疗装置的储能电容器由二次电池驱动。 主电池用作再次充电二次电池的能量源。

公开(公告)号：US20060111752A1

公开(公告)日：2006-05-25

申请号：US10994565

申请日：2004-11-22

Applicant: Wilson Greatbatch ,  Jeffrey Deal

Inventor： Wilson Greatbatch ,  Jeffrey Deal

IPC: A61N1/378

CPC classification number: A61N1/3975 ,  A61N1/3787 ,  H01M10/052 ,  H01M10/44 ,  H01M10/441 ,  H01M10/46

Abstract: A high energy battery power source suitable for use in an implantable medical device includes an input, an output, and two or more battery modules each comprising two or more battery cells. The battery cells are of relatively low voltage and permanently configured within each battery module in an electrically parallel arrangement in order to provide a desired current discharge level needed to achieve high-energy output. A switching system configures the battery modules between a first configuration wherein the battery modules are electrically connected in parallel to each other and to the input in order to receive charging energy at the relatively low voltage, and a second configuration wherein the battery modules are electrically connected in series to each other in order to provide to the output a relatively high voltage corresponding to the number of battery modules at a current level corresponding to the number of battery cells in a single battery module.

Abstract translation: 适用于可植入医疗装置的高能量电池电源包括输入端，输出端和两个或更多个电池模块，每个电池模块包括两个或多个电池单元。 电池单元具有相对低的电压并且以电并联的方式永久地配置在每个电池模块内，以便提供实现高能量输出所需的期望的电流放电水平。 交换系统将电池模块配置在第一配置之间，其中电池模块彼此并联电连接到输入端，以便在相对低的电压下接收充电能量;以及第二配置，其中电池模块电连接 彼此串联，以向输出提供对应于在单个电池模块中与电池单元的数量相对应的当前电平的电池模块的数量的相对高的电压。

公开(公告)号：US07020519B2

公开(公告)日：2006-03-28

申请号：US10407916

申请日：2003-04-04

Applicant: Wilson Greatbatch ,  Jeffrey Deal

Inventor： Wilson Greatbatch ,  Jeffrey Deal

IPC: A61N1/18

CPC classification number: H01M16/00 ,  A61N1/378 ,  H01M6/16 ,  H01M6/5016 ,  H01M6/5033 ,  H01M10/052 ,  H01M10/0525 ,  H02J7/0054

Abstract: A hybrid battery power source for implantable medical use provides a generally constant low internal resistance during discharge and avoids voltage delays of the type that develop as a result of run down-induced resistance increase in Li/SVO cells. The hybrid battery power source utilizes two batteries or cells, one being a primary cell of relatively high energy density and the other being a secondary cell of relatively low internal resistance that is rechargeable. The primary and secondary cells are connected in a parallel arrangement via a voltage boost/charge control circuit that is powered by the primary cell and adapted to charge the secondary cell while limiting charge/discharge excursions thereof in a manner that optimizes its output for high energy medical device use. The energy storage capacitors of the medical device in which the hybrid battery power source is situated are driven by the secondary cell. The primary cell is used to as an energy source for recharging the secondary cell.

公开(公告)号：US4314554A

公开(公告)日：1982-02-09

申请号：US57744

申请日：1979-07-16

Applicant: Wilson Greatbatch

Inventor： Wilson Greatbatch

IPC: A61N1/18 ,  A61B17/58 ,  A61F2/28 ,  A61N1/08 ,  A61N1/20 ,  A61N1/32 ,  A61N1/372 ,  A61N1/30

CPC classification number: A61B17/58 ,  A61N1/08 ,  A61N1/205 ,  A61N1/326 ,  A61N1/372 ,  A61F2002/2821

Abstract: A method and apparatus for providing germicidal and healing treatment of tissue such as bone wherein an electrode of silver or like material is applied to a living tissue site to be healed, initially a direct voltage is applied to the electrode of a polarity driving the electrode as an anode to release silver ions to create a germicidal environment at the site, and thereafter a direct voltage of opposite polarity is applied to the electrode driving it as a cathode to stimulate healing of the tissue at the site. The apparatus is implanted in the body of a patient, and in one embodiment a battery is connected through a switch to the electrode and a reference electrode, the switch initially connecting the electrode as an anode and thereafter changeable by an external operator such as a magnet to connect the electrode as a cathode. In another embodiment, another electrode and an element cooperate with the treating electrode to form a galvanic couple with the treating electrode to create a germicidal environment and a predetermined time thereafter the arrangement changes to a biogalvanic couple with body fluid to cause healing of the tissue. In either embodiment a wave shaping circuit can be operatively associated with the treating electrode to facilitate external monitoring of the apparatus when implanted.

Abstract translation: 一种用于提供诸如骨的组织的杀菌和愈合治疗的方法和装置，其中将银或类似材料的电极施加到待愈合的生物体组织部位，最初将直流电压施加到驱动电极的极性的电极，如 阳极以释放银离子以在该位置产生杀菌环境，之后将极性相反的直流电压施加到驱动其作为阴极的电极上，以刺激该部位组织的愈合。 该装置植入患者体内，在一个实施例中，电池通过开关连接到电极和参考电极，开关最初将电极连接为阳极，然后可由诸如磁体的外部操作者 将电极连接成阴极。 在另一个实施方案中，另一个电极和元件与处理电极配合，以与处理电极形成电偶，以产生杀菌环境，此后，预定时间将布置改变为与体液的生物金属联接，从而引起组织愈合。 在任一实施例中，波形整形电路可以与处理电极可操作地相关联，以便于在植入时对装置进行外部监测。

公开(公告)号：US4294256A

公开(公告)日：1981-10-13

申请号：US57745

申请日：1979-07-16

Applicant: Wilson Greatbatch

Inventor： Wilson Greatbatch

IPC: A61N1/362 ,  A61N1/372 ,  A61N1/36

CPC classification number: A61N1/37211

Abstract: An artificial cardiac pacer including a pulse source of relatively high and constant frequency, such as a quartz crystal oscillator, and a frequency divider for converting the source pulses to a lower frequency suitable for application to pacer electrodes for heart stimulation is provided with a pulse rate controller operatively connected to the frequency converter for inhibiting a predetermined number of pulses in each time interval to change the frequency of pulses applied to the pacer electrodes. An external controller operatively coupled to the pulse rate control generates first and second command signals in response to manual selection which are received by the pulse rate control and cause an increase or decrease in the number of pulses inhibited.

Abstract translation: 提供了包括相对高和恒定频率的脉冲源的人造心脏起搏器，例如石英晶体振荡器和用于将源脉冲转换成适合于用于心脏刺激的起搏电极的较低频率的分频器，脉冲频率 控制器可操作地连接到变频器，用于在每个时间间隔中抑制预定数量的脉冲，以改变施加到起搏器电极的脉冲频率。 可操作地耦合到脉搏速率控制的外部控制器响应于由脉冲速率控制接收的手动选择产生第一和第二命令信号，并且导致抑制的脉冲数量的增加或减少。

公开(公告)号：US4135519A

公开(公告)日：1979-01-23

申请号：US853136

申请日：1977-11-21

Applicant: Wilson Greatbatch

Inventor： Wilson Greatbatch

IPC: A61N1/378 ,  H01M4/36 ,  H01M4/38 ,  H01M6/18 ,  A61N1/36

CPC classification number: H01M4/388 ,  A61N1/378 ,  H01M4/36 ,  H01M4/364 ,  H01M6/182

Abstract: A cardiac pacer having an alkali metal-halogen cell comprising an alkali metal anode, preferably lithium, a solid alkali metal-halogen electrolyte and a cathode comprising a mixture of two halogens, for example iodine and bromine, the two halogens providing discharge of the cell at two different levels of cell output voltage. The two halogens are in different proportions by weight of the mixture thereby providing a two step output voltage-time characteristic. The second step or plateau in the output voltage characteristic provides an early warning of pacer battery exhaustion.

Abstract translation: 一种具有碱金属卤素电池的心脏起搏器，其包含碱金属阳极，优选锂，固体碱金属 - 卤素电解质和包含两种卤素如碘和溴的混合物的阴极，所述两种卤素提供电池的放电 在两个不同级别的电池输出电压。 两种卤素按混合物的重量不同，由此提供两步输出电压 - 时间特性。 输出电压特性的第二步或平台提供了电池耗尽的预警。

公开(公告)号：US4128703A

公开(公告)日：1978-12-05

申请号：US812641

申请日：1977-07-05

Applicant: Ralph T. Mead ,  Wilson Greatbatch ,  Frank W. Rudolph ,  Norbert W. Frenz, Jr.

Inventor： Ralph T. Mead ,  Wilson Greatbatch ,  Frank W. Rudolph ,  Norbert W. Frenz, Jr.

IPC: H01M2/02 ,  H01M6/18

CPC classification number: H01M6/182

Abstract: A lithium-iodine cell comprising a casing of electrically conducting material, an anode including a lithium element within the casing, an electrical conductor operatively connected to the lithium element and extending out from the casing, and a cathode comprising iodine-containing material in operative contact with both the casing and the lithium element. The anode electrical conductor is completely sealed from the rest of the cell, and the casing serves as the cathode current collector. The anode operative surface is provided with a coating of an organic electron donor material. The anode is enclosed within an insulator element within the casing and a ferrule having one end within the insulator and the other end extending from the casing.

Abstract translation: 一种锂 - 碘电池，包括导电材料的壳体，在壳体内包含锂元素的阳极，可操作地连接到锂元素并从壳体延伸出来的电导体，以及包含操作接触的含碘材料的阴极 与壳体和锂元素。 阳极电导体与电池的其余部分完全密封，并且壳体用作阴极集电器。 阳极工作表面设置有有机电子给体材料的涂层。 阳极被封装在壳体内的绝缘体元件内，并且套管具有在绝缘体内的一端，另一端从壳体延伸。

公开(公告)号：US4071662A

公开(公告)日：1978-01-31

申请号：US647002

申请日：1976-01-07

Applicant: Ralph T. Mead ,  Wilson Greatbatch ,  Frank W. Rudolph

Inventor： Ralph T. Mead ,  Wilson Greatbatch ,  Frank W. Rudolph

IPC: H01M4/06 ,  H01M6/18 ,  H01M2/02

CPC classification number: H01M4/06 ,  H01M6/182

Abstract: A lithium-iodine cell comprising a cathode including a charge transfer complex of an organic donor component and iodine, an anode including a lithium element having a surface operatively contacting the charge transfer complex material, and a coating on the lithium surface of an organic electron donor material, preferably but not necessarily the organic donor component of the charge transfer complex. The organic electron donor material preferably comprises polyvinyl pyridine polymer and in particular two-vinyl pyridine polymer. A solution of two-vinyl pyridine polymer in benzene is brushed onto the anode lithium surface and then exposed to a desiccant. A number of coatings preferably are applied successively to provide a resulting or finished coating of increased thickness.

Abstract translation: 一种锂碘电池，其包含阴极，其包括有机供体组分和碘的电荷转移络合物，包含具有可操作地接触电荷转移络合物材料的表面的锂元素的阳极和有机电子给体的锂表面上的涂层 材料，优选但不一定是电荷转移络合物的有机供体组分。 有机电子给体材料优选包含聚乙烯基吡啶聚合物，特别是二乙烯基吡啶聚合物。 将二乙烯基吡啶聚合物在苯中的溶液刷在阳极锂表面上，然后暴露于干燥剂中。 优选连续施加多个涂层以提供增加厚度的所得或成品涂层。

公开(公告)号：US06988001B2

公开(公告)日：2006-01-17

申请号：US10283530

申请日：2002-10-30

Applicant: Wilson Greatbatch ,  Michael L. Weiner

Inventor： Wilson Greatbatch ,  Michael L. Weiner

IPC: A61N1/362

CPC classification number: A61N1/056 ,  A61N1/0565

Abstract: A hermetic component housing for use with a photonic catheter connected to a photonic pacemaker or other medical system designed for compatibility with Magnetic Resonance Imaging (MRI) procedures. The hermetic housing includes a housing body having a proximal end and a distal end. The body is formed with a hermetically sealed interior for carrying one or more electrical and/or optical components therein. The proximal end of the body is adapted to mount to a distal end of a photonic catheter carrying a fiber optic element or bundle. A hermetic terminal is provided to allow the fiber optic element or bundle to communicate with the body interior. The body can be adapted to mount (or function as) one or more electrodes designed for delivering or sensing electrical signals to body tissue, or it may be adapted to mount no electrodes. The component housing may be implemented by itself at the distal end of the photonic catheter, or it may be used in conjunction with other housings of like or different construction.