公开(公告)号：US5179004A

公开(公告)日：1993-01-12

申请号：US454189

申请日：1989-12-21

申请人： Anton Haselbeck ,  Wolfgang Hosel ,  Herbert von der Eltz ,  Edith Schickaneder

发明人： Anton Haselbeck ,  Wolfgang Hosel ,  Herbert von der Eltz ,  Edith Schickaneder

IPC分类号： G01N33/53 ,  G01N33/536 ,  G01N33/543 ,  G01N33/58 ,  G01N33/68

CPC分类号： G01N33/68 ,  G01N33/5308 ,  G01N33/583 ,  Y10S435/961

摘要： For the detection of compounds containing carbohydrate the compound to be detected is reacted with a conjugate which contains a group which enables a specific binding to the substance to be detected and contains a hapten with a molecular weight from 300 to 1200, afterwards the complex formed is brought into contact with labelled antibodies directed against the hapten and the label is determined in a known way.

摘要翻译： 为了检测含有碳水化合物的化合物，将要检测的化合物与含有能够与被检测物质特异性结合的基团的缀合物反应，并含有分子量为300〜1200的半抗原，之后形成的复合物为 与针对半抗原的标记抗体接触，并以已知的方式测定标记。

公开(公告)号：US20060080040A1

公开(公告)日：2006-04-13

申请号：US11112919

申请日：2005-04-22

申请人： Ursula Garczarek ,  Pavel Kubalec ,  Wolfgang Hosel

发明人： Ursula Garczarek ,  Pavel Kubalec ,  Wolfgang Hosel

IPC分类号： G06F19/00

CPC分类号： G01N30/8624 ,  G01N30/8682 ,  G01N2030/862 ,  H01J49/0027

摘要： The invention provides a method for grouping measurement data obtained by effecting two or more techniques to provide characterization data characterizing at least one sample with respect to characterizing substances. According to one aspect of the invention, the grouping is effected on the basis of at least one statistical distribution of deviations (Δm/zi) of a respective characterizing measurement value. According to another aspect of the invention, the grouping is effected on the basis of at least one collective characteristic of a plurality of respective quantitative measurement values (Ii).

摘要翻译： 本发明提供了一种用于对通过实施两种或多种技术获得的测量数据进行分组的方法，以提供表征关于特征物质的至少一个样品的表征数据。 根据本发明的一个方面，基于相应特征测量值的偏差的至少一个统计分布（Deltam / zI i），进行分组。 根据本发明的另一方面，基于多个相应的定量测量值（I SUB）的至少一个集合特征进行分组。

公开(公告)号：US6136545A

公开(公告)日：2000-10-24

申请号：US926452

申请日：1997-09-10

申请人： Wolfgang Hosel ,  Wolfgang Mutter

发明人： Wolfgang Hosel ,  Wolfgang Mutter

IPC分类号： G01N33/543 ,  G01N33/536 ,  G01N33/546 ,  G01N33/554

CPC分类号： G01N33/54313

摘要： The invention concerns a method for the determination of an analyte in a sample liquid wherein the sample liquid is incubated with (a) a first receptor which binds to a first epitope that is only present once on the analyte and is immobilized on a particulate carrier material and (b) a second receptor which binds to a second epitope on the analyte and has at least two binding sites for the second epitope, the first epitope being different from the second epitope and the analyte is determined by means of the binding to both receptors.

摘要翻译： 本发明涉及一种用于测定样品液体中分析物的方法，其中将样品液体与（a）第一受体温育，第一受体与仅在分析物上存在一次的第一表位结合并固定在颗粒载体材料上 和（b）第二受体，其结合分析物上的第二表位并且具有至少两个第二表位的结合位点，第一表位不同于第二表位，分析物通过结合两个受体来测定 。

公开(公告)号：US06635420B1

公开(公告)日：2003-10-21

申请号：US09508138

申请日：2000-10-13

申请人： Wolfgang Hosel ,  Helmut Lenz ,  Jochen Peter

发明人： Wolfgang Hosel ,  Helmut Lenz ,  Jochen Peter

IPC分类号： G01N3353

CPC分类号： C07K1/22 ,  B01D15/3804 ,  B01D15/422 ,  Y10S435/803 ,  Y10S435/81 ,  Y10S435/814 ,  Y10S435/815 ,  Y10S435/971 ,  Y10S435/975 ,  Y10S436/823 ,  Y10S436/824

摘要： The invention concerns a method for the purification of a target substance from a biological sample by immobilizing the target substance on a solid phase by means of a high affinity binding pair and subsequently eluting it by adding a partner of the binding pair in a free form. In addition reagent kits for carrying out the method are disclosed.

摘要翻译： 本发明涉及通过用高亲合力结合对将目标物质固定在固相上并随后通过以游离形式加入结合对的伴侣来洗脱来从生物样品中纯化目标物质的方法。 此外，公开了用于实施该方法的试剂盒。