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    REAGENTS AND METHODS FOR DETECTING INFLUENZA VIRUS PROTEINS
    2.
    发明申请
    REAGENTS AND METHODS FOR DETECTING INFLUENZA VIRUS PROTEINS 审中-公开
    用于检测流感病毒蛋白的试剂和方法

    公开(公告)号：US20120141519A1

    公开(公告)日：2012-06-07

    申请号：US13322459

    申请日：2010-05-28

    申请人： Xuguang Li ,  Runtao He ,  Gary Van Domselaar

    发明人： Xuguang Li ,  Runtao He ,  Gary Van Domselaar

    IPC分类号： A61K39/145 ,  C07K16/10 ,  C07K1/00 ,  A61P31/16 ,  C12P21/08 ,  G01N33/573 ,  C12N9/96 ,  A61P37/04

    CPC分类号： G01N33/56983 ,  A61K39/12 ,  A61K39/145 ,  A61K2039/505 ,  A61K2039/55566 ,  A61K2039/6081 ,  C07K16/1018 ,  C07K16/40 ,  C07K2317/34 ,  C12N9/2402 ,  C12N2760/16134 ,  C12Y302/01018 ,  G01N33/573 ,  G01N2333/924 ,  G01N2333/9506

    摘要： Two universally conserved sequences from influenza type A neuraminidases were identified by large scale sequence analysis then chemically modified and conjugated to carrier proteins to generate mono-specific and monoclonal antibodies. The two antibodies, one targeting the N-terminus of the type A neuraminidase and the other sequence close to enzymatic active site, were capable of binding to all 9 subtypes of neuraminidase while demonstrating remarkable specificity against the viral neuraminidase sequences since no cross-reactivity against allantoic proteins was observed. Quantitative analyses of NA using slot blot suggest that the antibodies can be used for NA antigen quantitation in vaccines. These represent the first time the antibody-based immunoassay can be used for NA quantitative determination.

    摘要翻译： 通过大规模序列分析鉴定了来自甲型流感A型神经氨酸酶的两种普遍保守的序列，然后化学修饰并与载体蛋白缀合以产生单特异性和单克隆抗体。 靶向A型神经氨酸酶的N末端的两种抗体和接近酶活性位点的其他序列能够结合所有9种亚型的神经氨酸酶，同时显示出对病毒神经氨酸酶序列的显着特异性，因为没有交叉反应 观察尿囊蛋白。 使用狭缝印迹的NA的定量分析表明抗体可用于疫苗中的NA抗原定量。 这些代表了首次基于抗体的免疫测定可用于NA定量测定。

    Method of preparing nano-level platinum/carbon electrocatalyst for cathode of fuel cell
    3.
    发明授权
    Method of preparing nano-level platinum/carbon electrocatalyst for cathode of fuel cell 失效
    制备燃料电池阴极纳米级铂/碳电催化剂的方法

    公开(公告)号：US06815391B2

    公开(公告)日：2004-11-09

    申请号：US10424215

    申请日：2003-04-25

    申请人： Wei Xing ,  Xuguang Li ,  Tianhong Lu

    发明人： Wei Xing ,  Xuguang Li ,  Tianhong Lu

    IPC分类号： H01M488

    CPC分类号： H01M4/92 ,  B01J21/18 ,  B01J23/42 ,  B01J37/16 ,  H01M4/926 ,  H01M2008/1095

    摘要： The present invention relates to a method for preparing nano-level Pt/C electrocatalyst for cathode of fuel cell. By employing ammonium chloride, potassium chloride, ammonium bromide, potassium bromide, ammonium iodide or potassium iodide as anchoring agent for the chloroplatinic acid, the present invention realizes the preparation of Pt/C electrocatalyst with platinum micro-particles homogeneously distributed in the interstices as well as on the surfaces of the active carbon. The sizes of the platinum particles in the catalyst are homogeneous and their average diameter is in the range of 2.5 to 4.5 mm. The present method is a novel one for preparing nanometer level Pt/C electrocatalyst. Said electrocatalyst possesses high specific activity per unit mass for the catalytic reduction of oxygen.

    Method for bit-stream data compression
    4.
    发明授权
    Method for bit-stream data compression 失效
    位流数据压缩方法

    公开(公告)号：US5684693A

    公开(公告)日：1997-11-04

    申请号：US557617

    申请日：1995-11-14

    申请人： Xuguang Li

    发明人： Xuguang Li

    IPC分类号： E21B47/12 ,  G01V1/42 ,  G06F19/00

    CPC分类号： G01V1/42 ,  E21B47/12 ,  G01V2210/161

    摘要： A plurality of sensors, each of which is coupled to a data channel, are mounted on a downhole logging tool for periodically measuring and sampling, at preselected timed sample intervals, petrophysical characteristics of the borehole sidewall material. The sample values are arranged in a two-dimensional array of a plurality of time series in channel-sequential order, indexed by consecutive sample number. Means are provided for transforming the plurality of time series from the time domain to the wavelet domain. The wavelet coefficients for each transformed time series are compressed by thresholding. The compressed wavelet coefficients corresponding to each time series are transmitted to a receiver where the compressed wavelet coefficients are decompressed by formatting same into a broken sequence of wavelet coefficients. The original time series is reconstructed by inversely transforming the broken sequence of wavelet coefficients from the wavelet domain back to the time domain.

    摘要翻译： 多个传感器，每个传感器联接到数据通道，安装在井下测井工具上，以预定的定时采样间隔周期性地测量和采样钻​​孔侧壁材料的岩石物理特性。 样本值以通道顺序排列的多个时间序列的二维阵列排列，由连续样本数索引。 提供了用于将多个时间序列从时域变换为小波域的装置。 每个变换时间序列的小波系数通过阈值进行压缩。 对应于每个时间序列的压缩小波系数被发送到接收机，其中压缩小波系数通过将其格式化为小波系数的断裂序列来解压缩。 通过将小波系数的断裂序列从小波域反向变换到时域来重构原始时间序列。

    Reagents and methods for detecting influenza virus proteins
    5.
    发明授权
    Reagents and methods for detecting influenza virus proteins 有权
    用于检测流感病毒蛋白质的试剂和方法

    公开(公告)号：US08926982B2

    公开(公告)日：2015-01-06

    申请号：US13322459

    申请日：2010-05-28

    申请人： Xuguang Li ,  Runtao He ,  Gary Van Domselaar

    发明人： Xuguang Li ,  Runtao He ,  Gary Van Domselaar

    IPC分类号： A61K39/145 ,  C07K16/10 ,  G01N33/569 ,  G01N33/573 ,  C12N9/24 ,  A61K39/00

    CPC分类号： G01N33/56983 ,  A61K39/12 ,  A61K39/145 ,  A61K2039/505 ,  A61K2039/55566 ,  A61K2039/6081 ,  C07K16/1018 ,  C07K16/40 ,  C07K2317/34 ,  C12N9/2402 ,  C12N2760/16134 ,  C12Y302/01018 ,  G01N33/573 ,  G01N2333/924 ,  G01N2333/9506

    摘要： Two universally conserved sequences from influenza type A neuraminidases were identified by large scale sequence analysis then chemically modified and conjugated to carrier proteins to generate mono-specific and monoclonal antibodies. The two antibodies, one targeting the N-terminus of the type A neuraminidase and the other sequence close to enzymatic active site, were capable of binding to all 9 subtypes of neuraminidase while demonstrating remarkable specificity against the viral neuraminidase sequences since no cross-reactivity against allantoic proteins was observed. Quantitative analyses of NA using slot blot suggest that the antibodies can be used for NA antigen quantitation in vaccines. These represent the first time the antibody-based immunoassay can be used for NA quantitative determination.

    摘要翻译： 通过大规模序列分析鉴定了来自甲型流感A型神经氨酸酶的两种普遍保守的序列，然后化学修饰并与载体蛋白缀合以产生单特异性和单克隆抗体。 靶向A型神经氨酸酶的N末端的两种抗体和接近酶活性位点的其他序列能够结合所有9种亚型的神经氨酸酶，同时显示出对病毒神经氨酸酶序列的显着特异性，因为没有交叉反应 观察尿囊蛋白。 使用狭缝印迹的NA的定量分析表明抗体可用于疫苗中的NA抗原定量。 这些代表了首次基于抗体的免疫测定可用于NA定量测定。

    Ground fault circuit interrupter
    6.
    发明授权
    Ground fault circuit interrupter 失效
    接地故障电路断路器

    公开(公告)号：US07692904B2

    公开(公告)日：2010-04-06

    申请号：US11901759

    申请日：2007-09-18

    申请人： Xuguang Li ,  Xiaobing Dong ,  Yi Yin

    发明人： Xuguang Li ,  Xiaobing Dong ,  Yi Yin

    IPC分类号： H02H3/00

    CPC分类号： H02H11/002

    摘要： A method of preventing an overload current from a power supply to a load through a ground fault circuit interrupter includes the steps of: obtaining an interrupted fault current from a hot wire to a ground wire via a first zero-phase current inductor and a fault current from a neutral wire to the ground wire via a second zero-phase current inductor; amplifying a signal of the fault current by an Op-Amp; and determining the fault current by a programmable control module, wherein when the fault current is larger than a preset threshold, the programmable control module sends a control signal to a control switch such that the control switch electrifies a second coil of a trip breaker to drive an armature at an unlocked position, so as to separate a movable terminal with a fixed terminal for electrically disconnecting the load with the power supply.

    摘要翻译： 通过接地故障电路断续器防止来自电源到负载的过载电流的方法包括以下步骤：经由第一零相电流电感器和故障电流从热线到接地线获得中断的故障电流 通过第二个零相电流电感从中性线到地线; 通过Op-Amp放大故障电流的信号; 以及通过可编程控制模块确定所述故障电流，其中当所述故障电流大于预设阈值时，所述可编程控制模块向控制开关发送控制信号，使得所述控制开关使跳闸断路器的第二线圈通电以驱动 电枢处于解锁位置，以便将可移动端子与固定端子分开，以使电源与电源电断开。

    Seismic data acquisition system
    8.
    发明授权
    Seismic data acquisition system 失效
    地震数据采集系统

    公开(公告)号：US5600318A

    公开(公告)日：1997-02-04

    申请号：US396128

    申请日：1995-02-28

    申请人： Xuguang Li

    发明人： Xuguang Li

    IPC分类号： G01V1/24 ,  H04B14/04 ,  G06F15/00

    CPC分类号： G01V1/247

    摘要： The present invention is a method of processing digitized signal samples generated by a free running analog-to-digital converter and sampled at a first sample rate. The method includes the steps of convolving the digitized signal samples with a single-stage digital filter and generating a series of resampled signal samples having a second sample rate no greater than the first sample rate. The resampled signal samples are synchronized with a predetermined time reference during the step of generating the series of resampled signal samples.The present invention is also an apparatus for recording seismic surveys. The apparatus comprises: a delta-sigma analog-to-digital converter; a means for calculating an average of a plurality of outputs of the delta-sigma converter; a means for subtracting the average from a single output of the converter; and a single-stage digital filter which has the capability of synchronizing digital signal samples from the delta-sigma converter to a predetermined time reference and can resample the digital signal samples to a lower sampling rate than that rate provided by the delta-sigma converter.

    摘要翻译： 本发明是一种处理由自由运行的模数转换器产生并以第一采样率采样的数字化信号采样的方法。 该方法包括以下步骤：将数字化信号样本与单级数字滤波器进行卷积，并产生具有不大于第一采样率的第二采样率的一系列重采样信号样本。 在产生一系列重采样信号样本的步骤期间，重新采样的信号样本与预定的时间基准同步。 本发明也是用于记录地震勘测的装置。 该装置包括：Δ-Σ模数转换器; 用于计算所述Δ-Σ转换器的多个输出的平均值的装置; 用于从转换器的单个输出中减去平均值的装置; 以及具有将来自Δ-Σ转换器的数字信号样本与预定时间基准同步的能力的单级数字滤波器，并且可以将数字信号样本重新采样到比由Δ-Σ转换器提供的速率更低的采样速率。

    Ground fault circuit interrupter
    10.
    发明申请
    Ground fault circuit interrupter 失效
    接地故障电路断路器

    公开(公告)号：US20080225448A1

    公开(公告)日：2008-09-18

    申请号：US11901759

    申请日：2007-09-18

    申请人： Xuguang Li ,  Xiaobing Dong ,  Yi Yin

    发明人： Xuguang Li ,  Xiaobing Dong ,  Yi Yin

    IPC分类号： H02H3/04

    CPC分类号： H02H11/002

    摘要： A method of preventing an overload current from a power supply to a load through a ground fault circuit interrupter includes the steps of: obtaining an interrupted fault current from a hot wire to a ground wire via a first zero-phase current inductor and a fault current from a neutral wire to the ground wire via a second zero-phase current inductor; amplifying a signal of the fault current by an Op-Amp; and determining the fault current by a programmable control module, wherein when the fault current is larger than a preset threshold, the programmable control module sends a control signal to a control switch such that the control switch electrifies a second coil of a trip breaker to drive an armature at an unlocked position, so as to separate a movable terminal with a fixed terminal for electrically disconnecting the load with the power supply.

    摘要翻译： 通过接地故障电路断续器防止来自电源到负载的过载电流的方法包括以下步骤：经由第一零相电流电感器和故障电流从热线到接地线获得中断的故障电流 通过第二个零相电流电感从中性线到地线; 通过Op-Amp放大故障电流的信号; 以及通过可编程控制模块确定所述故障电流，其中当所述故障电流大于预设阈值时，所述可编程控制模块向控制开关发送控制信号，使得所述控制开关使跳闸断路器的第二线圈通电以驱动 电枢处于解锁位置，以便将可移动端子与固定端子分开，以使电源与电源电断开。