公开(公告)号：US5422576A

公开(公告)日：1995-06-06

申请号：US90725

申请日：1993-07-13

Applicant: Yi-Hsuan Kao ,  Patrick A. Turski ,  Stefan S. Winkler

Inventor： Yi-Hsuan Kao ,  Patrick A. Turski ,  Stefan S. Winkler

IPC: G01R33/56 ,  G01R33/561 ,  G01R33/563 ,  G01R33/20

CPC classification number: G01R33/5615 ,  G01R33/563 ,  G01R33/5608 ,  G01R33/5617 ,  G01R33/56316

Abstract: An NMR system performs a dual-echo fast-spin-echo scan to acquire two NMR data sets from which proton density-weighted and T.sub.2 -weighted images may be reconstructed. The two NMR data sets are combined to produce a composite NMR data set from which a black blood NMR angiogram is produced by a minimum intensity projection.

Abstract translation: NMR系统执行双重回波快速自旋回波扫描，以获得可重构质子密度加权和T2加权图像的两个NMR数据集。 组合两个NMR数据集以产生由最小强度投影产生黑血核磁共振血管造影图的复合NMR数据集。

公开(公告)号：US08427151B2

公开(公告)日：2013-04-23

申请号：US13007357

申请日：2011-01-14

Applicant: Yi-Hsuan Kao ,  Mu-Huo Teng ,  Wen-Yan Zheng ,  Yu-Fen Chen

Inventor： Yi-Hsuan Kao ,  Mu-Huo Teng ,  Wen-Yan Zheng ,  Yu-Fen Chen

IPC: G01V3/00

CPC classification number: A61B5/055 ,  A61B5/0042 ,  A61B5/0263 ,  A61B5/4064 ,  A61B5/7264 ,  G06T7/0016 ,  G06T7/11 ,  G06T7/136 ,  G06T7/174 ,  G06T2207/10096 ,  G06T2207/20076 ,  G06T2207/20224 ,  G06T2207/30016

Abstract: The present invention discloses a method and apparatus for brain perfusion magnetic resonance imaging (MRI) technique with the removal of cerebrospinal fluid (CSF) pixels. This invention utilizes a CSF/brain-contrast-enhanced image, wherein the CSF/brain-contrast-enhanced image is defined as the signal difference between CSF and brain matter divided by a standard deviation of air background random noise is larger than 3, acquired from the subject's brain, and applies a segmentation technique to remove the CSF pixels. After removing the CSF pixels on parametric images, the extent of brain tissue with delayed perfusion can be better identified. By using a good region of interest enclosing the correct delayed-perfusion region, the measurement on the tissue volume and perfusion parameters would be more accurate than the area contaminated by CSF pixels.

Abstract translation: 本发明公开了脑灌注磁共振成像（MRI）技术与去除脑脊液（CSF）像素的方法和装置。 本发明利用CSF /脑对比度增强图像，其中CSF /脑对比度增强图像被定义为CSF与脑部之间的信号差除以空气背景随机噪声的标准偏差大于3，获得 从受试者的脑部，并应用分割技术去除CSF像素。 在去除参数图像上的CSF像素后，可以更好地识别具有延迟灌注的脑组织的程度。 通过使用包围正确的延迟灌注区域的良好感兴趣区域，组织体积和灌注参数的测量将比被CSF像素污染的区域更准确。

公开(公告)号：US5361763A

公开(公告)日：1994-11-08

申请号：US025004

申请日：1993-03-02

Applicant: Yi-Hsuan Kao ,  James A. Sorenson ,  Mark M. Bahn

Inventor： Yi-Hsuan Kao ,  James A. Sorenson ,  Mark M. Bahn

IPC: A61B5/055 ,  G01R33/56 ,  G06T1/00 ,  G06T5/00 ,  G06T7/00

CPC classification number: G06T7/606 ,  G01R33/56 ,  G06T7/0081 ,  G01R33/5608 ,  G06T2207/10081 ,  G06T2207/30096

Abstract: A dual echo magnetic resonance imaging system produces two registered images of a patient in which the images have different contrast relationships between different tissue types. A two dimensional feature space histogram of the two images is produced and a separate centroid is located in the feature space histogram for each one of a pair of tissue types. A Cartesian coordinate system is defined in the feature space so that one axis of the system passes through the two centroids. Vector decomposition is employed to project each image element data point in the feature space onto a point on the one axis. The fractional quantity of each tissue type present in the image element is determined based upon the Euclidean distances from that axis point to the respective centroids. The fractional quantity is calculated for each element in the original images to form a pair of tissue images. The elements of a tissue image are processed to measure the amount of that tissue type in the imaged portion of the patient.

Abstract translation: 双回波磁共振成像系统产生患者的两个记录图像，其中图像在不同组织类型之间具有不同的对比度关系。 产生两个图像的二维特征空间直方图，并且单个质心位于一对组织类型中的每一个的特征空间直方图中。 在特征空间中定义笛卡尔坐标系，使系统的一个轴穿过两个质心。 矢量分解用于将特征空间中的每个图像元素数据点投影到一个轴上的点上。 基于从该轴点到各个质心的欧几里德距离来确定存在于图像元素中的每种组织类型的分数。 对原始图像中的每个元素计算分数，以形成一对组织图像。 处理组织图像的元件以测量患者的成像部分中的组织类型的量。

公开(公告)号：US20120184843A1

公开(公告)日：2012-07-19

申请号：US13007357

申请日：2011-01-14

Applicant: Yi-Hsuan Kao ,  Mu-Huo Teng ,  Wen-Yan Zheng ,  Yu-Fen Chen

Inventor： Yi-Hsuan Kao ,  Mu-Huo Teng ,  Wen-Yan Zheng ,  Yu-Fen Chen

IPC: A61B5/055 ,  G06K9/00

CPC classification number: A61B5/055 ,  A61B5/0042 ,  A61B5/0263 ,  A61B5/4064 ,  A61B5/7264 ,  G06T7/0016 ,  G06T7/11 ,  G06T7/136 ,  G06T7/174 ,  G06T2207/10096 ,  G06T2207/20076 ,  G06T2207/20224 ,  G06T2207/30016

Abstract: The present invention discloses a method and apparatus for brain perfusion magnetic resonance imaging (MRI) technique with the removal of cerebrospinal fluid (CSF) pixels. This invention utilizes a CSF/brain-contrast-enhanced image, wherein the CSF/brain-contrast-enhanced image is defined as the signal difference between CSF and brain matter divided by a standard deviation of air background random noise is larger than 3, acquired from the subject's brain, and applies a segmentation technique to remove the CSF pixels. After removing the CSF pixels on parametric images, the extent of brain tissue with delayed perfusion can be better identified. By using a good region of interest enclosing the correct delayed-perfusion region, the measurement on the tissue volume and perfusion parameters would be more accurate than the area contaminated by CSF pixels.

Abstract translation: 本发明公开了脑灌注磁共振成像（MRI）技术与去除脑脊液（CSF）像素的方法和装置。 本发明利用CSF /脑对比度增强图像，其中CSF /脑对比度增强图像被定义为CSF与脑部之间的信号差除以空气背景随机噪声的标准偏差大于3，获得 从受试者的脑部，并应用分割技术去除CSF像素。 在去除参数图像上的CSF像素后，可以更好地识别具有延迟灌注的脑组织的程度。 通过使用包围正确的延迟灌注区域的良好感兴趣区域，组织体积和灌注参数的测量将比被CSF像素污染的区域更准确。

公开(公告)号：US20130322718A1

公开(公告)日：2013-12-05

申请号：US13486974

申请日：2012-06-01

Applicant: Yi-Hsuan KAO ,  Michael Mu Huo Teng ,  Yi-Tzu Kao

Inventor： Yi-Hsuan KAO ,  Michael Mu Huo Teng ,  Yi-Tzu Kao

IPC: G06K9/00

CPC classification number: G06T11/008 ,  G06T2211/404 ,  G06T2211/412

Abstract: The present invention discloses a method and apparatus for measuring AIF and VOF on brain perfusion CT images. The AIF and VOF are used to calculate hemodynamic parameters. In this invention, bone voxels and neighboring voxels are removed first from the perfusion images and thus only brain voxels are included in the AIF and VOF measurement procedures; moreover, the selection criteria, such as large area under the concentration-time curve, early arrival of contrast agents, and narrow effective width, are used to select appropriate arterial and venous voxels for the AIF and VOF measurements.

Abstract translation: 本发明公开了一种脑灌注CT图像测量AIF和VOF的方法和装置。 AIF和VOF用于计算血液动力学参数。 在本发明中，首先从灌注图像中去除骨体素和相邻的体素，因此在AIF和VOF测量程序中仅包括脑体素; 此外，使用选择标准，如浓度 - 时间曲线下的大面积，造影剂的早到，狭窄的有效宽度，用于为AIF和VOF测量选择合适的动脉和静脉体素。

公开(公告)号：US5785042A

公开(公告)日：1998-07-28

申请号：US388614

申请日：1995-02-14

Applicant: Yi-Hsuan Kao

Inventor： Yi-Hsuan Kao

IPC: G01R33/565 ,  A61B5/055

CPC classification number: G01R33/565

Abstract: A method for correcting striation artifacts that are generated during a magnetic resonance imaging method. The method involves generating an image of a body area. The image is reconstructed from raw data collected in a spatial-frequency domain. As some of the data points in the raw data from which the image is generated are corrupted, the image of the body area contains striation artifacts. A region containing a homogenous material is selected. Next, the corrupted data points in the raw data are detected and corrected vis-a-vis a Fourier transform correction process, and a new corrected image essentially free of striation artifacts is generated.

Abstract translation: 一种用于校正在磁共振成像方法期间产生的条纹伪影的方法。 该方法涉及生成身体区域的图像。 从空间频域收集的原始数据重建图像。 由于生成图像的原始数据中的某些数据点已损坏，因此身体区域的图像包含条纹工件。 选择含有均质材料的区域。 接下来，根据傅里叶变换校正处理检测和修正原始数据中的损坏的数据点，并且生成基本上没有条纹伪影的新的校正图像。