摘要:
Herein disclosed are therapeutic agents for renal diseases and organ preservatives containing a compound represented by the general formula (1): ##STR1## wherein X represents an oxygen atom or a group represented by the general formula (2): ##STR2## where n represents an integer from 0 to 2, R.sub.1 represents a hydrogen atom or an acyl group, R.sub.2 represents a hydrogen atom, a lower alkyl group or a lower alkenyl group, R.sub.3 represents a lower alkyl group, R.sub.4, R.sub.5 and R.sub.6, which may be the same or different, each represents a hydrogen atom or an optionally substituted alkyl group, and R.sub.6 further represents a formyl, carboxyl, lower alkoxycarbonyl or optionally substituted carbamoyl group, or R.sub.3 and R.sub.4 may be taken together to form a five-membered ring, or R.sub.5 and R.sub.6 may be taken together to form a cycloalkyl group, provided that when the five-membered ring formed by R.sub.3 and R.sub.4 and the benzene ring form benzofuran or benzo[b]thiophene, R.sub.6 is absent.
摘要:
2,3-Dihydrobenzofuran derivatives of general formula (1): wherein R1 represents a hydrogen atom or an acyl group; R2, R3 and R4 represent a hydrogen atom, a lower alkyl group or a lower alkenyl group; R5 and R6 represent a hydrogen atom or an optionally substituted alkyl group, or R5 and R6 combine to form a cycloalkyl group or a saturated heterocyclic group containing one or more oxygen atoms or alkyl-substituted nitrogen atoms, provided that R2 and R3 can not simultaneously represent a t-butyl group, or optically active isomers or pharmaceutically acceptable salts thereof are useful as therapeutic or prophylactic agents for various renal diseases and as organ preservatives.
摘要翻译:通式(1)的2,3-二氢苯并呋喃衍生物:其中R1表示氢原子或酰基; R2,R3和R4表示氢原子,低级烷基或低级烯基; R 5和R 6表示氢原子或任选取代的烷基,或者R 5和R 6结合形成环烷基或含有一个或多个氧原子或烷基取代的氮原子的饱和杂环基,条件是R 2和R 3不能同时 代表叔丁基,或其光学活性异构体或其药学上可接受的盐可用作各种肾脏疾病的治疗剂或预防剂和作为器官防腐剂。
摘要:
A temperature-compensating method of a resistance bridge circuit constructed of a plurality of resistance devices, comprises: a first step of adjusting in direction and in curvature a temperature characteristic curve of an output signal issued from the resistance bridge circuit in which a resistor for temperature compensation is connected in parallel with one of a pair of the resistance devices, the pair being disposed in adjacent arms of the resistance bridge circuit; and a second step of applying an additional signal to the output signal of the resistance bridge circuit so as to offset the temperature variation of the output signal of the resistance bridge circuit.
摘要:
In the case where a battery is reversely connected, unnecessary current-carrying to a glow plug is avoided.Power MOS type field effect transistors 1-1 to 1-n are provided according to a number of glow plugs 5-1 to 5-n to be connected in series between a vehicle battery and the glow plugs 5-1 to 5-n and can be controlled in conduction or non-conduction by a glow-plug control part 51, while a MOS type field effect transistor 2 for protection against reverse connection is provided in series connection between a battery-power joining terminal 3, to which a positive voltage of a vehicle battery is applied, and the ground to cause a reverse current to flow to a fuse 4 through the MOS type field effect transistor 2 at the time of reverse connection of a battery to melt the fuse 4 early whereby current-carrying to the glow plugs 5-1 to 5-n can be avoided.
摘要:
An object of the present invention is to provide a pharmaceutical composition and a method for preventing or treating a respiratory disease. The pharmaceutical composition comprises a compound represented by formula (1): or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要:
2,3-Dihydrobenzofuran derivatives of general formula (1): wherein R1 represents a hydrogen atom or an acyl group; R2, R3 and R4 represent a hydrogen atom, a lower alkyl group or a lower alkenyl group; R5 and R6 combine to form a cycloalkyl group or a saturated heterocyclic group containing one or more oxygen atoms or sulfur atoms, provided that R2 and R3 can not simultaneously represent a t-butyl group, or optically active isomers or pharmaceutically acceptable salts thereof are useful as therapeutic or prophylactic agents for various renal diseases and as organ preservatives.
摘要翻译:通式(1)的2,3-二氢苯并呋喃衍生物:其中R1表示氢原子或酰基; R2,R3和R4表示氢原子,低级烷基或低级烯基; R 5和R 6结合形成含有一个或多个氧原子或硫原子的环烷基或饱和杂环基,条件是R 2和R 3不能同时代表叔丁基,或其光学活性异构体或药学上可接受的盐是有用的 作为各种肾脏疾病的治疗剂或预防剂和作为器官防腐剂。