公开(公告)号：US08575288B2

公开(公告)日：2013-11-05

申请号：US10517357

申请日：2003-05-21

申请人： Shinji Hayashi ,  Akitaka Nishio ,  Masami Okuo ,  Kensaku Sonoda ,  Chihiro Imase ,  Yoshikazu Nakashima

发明人： Shinji Hayashi ,  Akitaka Nishio ,  Masami Okuo ,  Kensaku Sonoda ,  Chihiro Imase ,  Yoshikazu Nakashima

IPC分类号： B05D5/00 ,  C08F20/00

CPC分类号： G02B5/223 ,  B82Y20/00 ,  G02B2207/101 ,  G02F1/133634

摘要： A curable resin composition is provided which uses a fumarate copolymer which is excellent in thermal discoloration resistance as a binder component and is capable of forming details of a color filter. The curable resin composition of the present invention is a photocurable resin composition for forming a protective layer, RGB pixels, a black matrix or a spacer of a color filter, and contains as a binder component a fumarate copolymer having at least a molecular structure wherein a constituent unit represented by the following Formula 1 and a constituent unit having an acidic functional group(s) are linked, preferably further having a constituent unit with an ethylenically unsaturated bond: wherein, each of R1 and R2 is independently a branched C3-8 alkyl group which may be substituted, or a C4-8 cycloalkyl group which may be substituted.

摘要翻译： 提供一种可固化树脂组合物，其使用作为粘合剂组分具有优异耐热变色性的富马酸盐共聚物，并且能够形成滤色器的细节。 本发明的固化性树脂组合物是形成保护层的光固化性树脂组合物，RGB像素，黑色矩阵或滤色器的间隔物，并且含有至少具有分子结构的富马酸酯共聚物作为粘合剂成分，其中， 由下式1表示的结构单元和具有酸性官能团的结构单元连接，优选进一步具有带有烯属不饱和键的构成单元：其中，R 1和R 2各自独立地为支链C 3-8烷基 可以被取代的基团，或可被取代的C4-8环烷基。

公开(公告)号：US07491408B2

公开(公告)日：2009-02-17

申请号：US10538799

申请日：2002-12-13

申请人： Atsuhiko Ogura ,  Shinji Tanaka ,  Yoshikazu Nakashima ,  Shigeru Kitano

发明人： Atsuhiko Ogura ,  Shinji Tanaka ,  Yoshikazu Nakashima ,  Shigeru Kitano

IPC分类号： A61L15/16 ,  A61F13/00 ,  C08G69/10

CPC分类号： A61L31/148 ,  A61L31/06 ,  C08G73/02 ,  C08G73/024 ,  C08G73/028 ,  C08L79/02

摘要： A novel A1-B-A2 polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1 and A2 each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1 is bonded to one end of segment B and segment A2 is bonded to the other end of segment B.

摘要翻译： 提供数均分子量为10000〜100000的新颖的A1-B-A2聚合物，其具有优异的生物吸收性，即使在体内大量嵌入时也能在规定时间内消失，具有良好的动力学性质， 并且可用于制备组织抗粘附膜。 该聚合物由具有至少修饰和未修饰的氨基酸组中的至少一个的片段A1和A2组成，由具有数均分子量为8000-50000的PEG构成的片段B.聚合物含有修饰和未修饰的氨基酸基团 ，改性氨基酸的含量为聚合物中全部氨基酸的20〜85摩尔％，段A1与段B的一端连接，段A2键合在段B的另一端。

公开(公告)号：US20060252908A1

公开(公告)日：2006-11-09

申请号：US10538799

申请日：2002-12-13

申请人： Atsuhiko Ogura ,  Shinji Tanaka ,  Yoshikazu Nakashima ,  Shigeru Kitano

发明人： Atsuhiko Ogura ,  Shinji Tanaka ,  Yoshikazu Nakashima ,  Shigeru Kitano

IPC分类号： C08G69/10

CPC分类号： A61L31/148 ,  A61L31/06 ,  C08G73/02 ,  C08G73/024 ,  C08G73/028 ,  C08L79/02

摘要： A novel A1-B-A2 polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1 and A2 each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1 is bonded to one end of segment B and segment A2 is bonded to the other end of segment B.

摘要翻译： 提供了数均分子量为10000〜100000的新型的高分子聚合物，其具有优异的生物吸收性，即使在预定时间内即使在 在体内大量嵌入，具有良好的动力学性质，对制备组织抗粘膜有用。 该聚合物由具有至少修饰的和未修饰的氨基酸基团中的至少一个的片段A 1和A 2组成，并且由具有数均分子量的PEG构成的片段B 该聚合物含有经修饰和未修饰的氨基酸基团，修饰氨基酸的含量为聚合物中所有氨基酸的20至85mol％，段A < 被结合到段B的一端，段A 2结合到段B的另一端。

公开(公告)号：US20110306985A1

公开(公告)日：2011-12-15

申请号：US12986848

申请日：2011-01-07

申请人： Takayuki INOUE ,  Koichi KURAMOTO ,  Yoshio NAKASHIMA ,  Naohiko SUGITA ,  Mamoru MITSUISHI ,  Yoshikazu NAKASHIMA

发明人： Takayuki INOUE ,  Koichi KURAMOTO ,  Yoshio NAKASHIMA ,  Naohiko SUGITA ,  Mamoru MITSUISHI ,  Yoshikazu NAKASHIMA

IPC分类号： A61B19/00

CPC分类号： G06T19/003 ,  A61B34/20 ,  A61B34/30 ,  A61B2034/107 ,  G06T15/08 ,  G06T2210/41

摘要： A surgical assistance system for operating on biological tissue using a surgical tool attached to an arm of an automatically-controlled surgical instrument so that an optimal feed rate of the tool is calculated and outputted to the surgical instrument, the system including: a device for storing and voxelizing medical image data obtained from a biological tissue subject to surgery; a device for setting an operative location based on the shape of the biological tissue; a device for calculating a tool path along which the tool travels to perform surgery at an operative location; a device for determining the region of interference between the tool and the voxels; a device for determining the hardness of the biological tissue in the interference region; a device for calculating an optimal tool feed rate corresponding to the hardness; and a device for outputting the feed rate obtained by the calculations to the surgical instrument.

摘要翻译： 一种外科辅助系统，用于使用附接到自动控制的手术器械的臂上的外科手术工具进行生物组织的操作，从而计算出所述工具的最佳进给速率并将其输出到所述手术器械，所述系统包括： 并且从进行手术的生物组织获得的医学图像数据的体素化; 用于基于生物组织的形状设置操作位置的装置; 用于计算工具行进的工具路径以在操作位置执行手术的装置; 用于确定所述工具与所述体素之间的干涉区域的装置; 用于确定干涉区域中生物组织的硬度的装置; 用于计算对应于硬度的最佳刀具进给速率的装置; 以及用于将通过计算获得的进给速率输出到外科器械的装置。

公开(公告)号：US20100247752A1

公开(公告)日：2010-09-30

申请号：US10517357

申请日：2003-05-21

申请人： Shinji Hayashi ,  Akitaka Nishio ,  Masami Okuo ,  Kensaku Sonoda ,  Chihiro Imase ,  Yoshikazu Nakashima

发明人： Shinji Hayashi ,  Akitaka Nishio ,  Masami Okuo ,  Kensaku Sonoda ,  Chihiro Imase ,  Yoshikazu Nakashima

IPC分类号： B05D5/00

CPC分类号： G02B5/223 ,  B82Y20/00 ,  G02B2207/101 ,  G02F1/133634

摘要： A curable resin composition containing as the binder a fumarate copolymer which is excellent in thermal discoloration resistance and capable of forming details of a color filter, namely, a photocurable resin composition useful in forming overcoats, RGB pixels, black matrixes or spacers in the production of color filters, which contains as the binder a fumarate copolymer having a molecular structure comprising constituent units represented by the general formula (1) and constituent units having acidic functional groups, and preferably further containing constituent units having ethylenically unsaturated bonds: (1) wherein R1 and R2 are each independently branched C3-8 alkyl which may be substituted, or C4-8 cycloalkyl which may be substituted.

摘要翻译： 一种固化性树脂组合物，其含有耐热变色性优异且能够形成滤色器的细节的富马酸盐共聚物，即在制备过涂层时可用于形成外涂层的可光固化树脂组合物，RGB像素，黑矩阵或间隔物 作为粘合剂的含有具有由通式（1）表示的构成单元和具有酸性官能团的构成单元的分子结构的富马酸盐共聚物，优选含有具有烯键式不饱和键的构成单元的粘合剂的滤色器：（1）其中R1 和R 2各自独立地为可被取代的分支的C 3-8烷基，或可被取代的C 4-8环烷基。