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公开(公告)号：US08551695B2
公开(公告)日：2013-10-08
申请号：US13355966
申请日：2012-01-23
Applicant: Margaret Dah-Tsyr Chang , Ping-Chiang Lyu , Yuh-Ju Sun , Chia-Chin Sheu
Inventor： Margaret Dah-Tsyr Chang , Ping-Chiang Lyu , Yuh-Ju Sun , Chia-Chin Sheu
IPC: C12Q1/00
CPC classification number: C12N15/62 , C07K2319/20 , C12N9/2428
Abstract: The present invention provides a method for identifying starch binding sites of starch binding domain in CBM family. The CBM family is consisting of CBM20, CBM21, CBM25, CBM26, CBM34, and CBM41. The method further comprises predicting starch binding sites of starch binding domain in CBM family using the identified starch binding sites of starch binding domain with same topology.
Abstract translation: 本发明提供了一种用于鉴定CBM系列中淀粉结合结构域的淀粉结合位点的方法。 CBM系列由CBM20，CBM21，CBM25，CBM26，CBM34和CBM41组成。 该方法还包括使用具有相同拓扑结构的淀粉结合域的确定的淀粉结合位点预测CBM家族中淀粉结合结构域的淀粉结合位点。
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2.发明申请POLYSACCHARIDE-PROTEIN BINDING MODEL AND NANO-FIBRIL FORMATION OF A STARCH BINDING DOMAIN 有权多糖 - 蛋白质结合模型和纳米纤维形成淀粉结合域公开(公告)号：US20110129853A1
公开(公告)日：2011-06-02
申请号：US13009650
申请日：2011-01-19
Applicant: Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
Inventor： Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
IPC: G01N33/53
CPC classification number: C12N9/2428 , C07K7/08 , C07K2319/00 , C12Y302/01003
Abstract: A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X1NNNX2X3NYQX4X5X6X7X8, wherein the X1 and X8 mean a pair of opposite charged amino acid residues, and the X2, X3, X4, X5, X6, or X7 means an amino acid residue is described. A mixture for diminising a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.
Abstract translation: SBD的多糖 - 蛋白质结合模型和由X1NNNX2X3NYQX4X5X6X7X8组成的原纤维形成的14残基肽，其中X1和X8表示一对相对带电的氨基酸残基，X2，X3，X4，X5，X6或 X7表示氨基酸残基。 还提供了用于减少多糖的混合物，其包含至少两种淀粉结合结构域（SBD）和螺旋形式的多糖。 进一步描述提供寡糖的方法和淀粉样样原纤维的生产方法及其用途。
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Patent Agency Ranking
3.发明授权Polysaccharide-protein binding model and nano-fibril formation of a starch binding domain 有权多糖 - 蛋白结合模型和淀粉结合结构域的纳米原纤维形成公开(公告)号：US07919580B2
公开(公告)日：2011-04-05
申请号：US12359035
申请日：2009-01-23
Applicant: Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
Inventor： Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
CPC classification number: C12N9/2428 , C07K7/08 , C07K2319/00 , C12Y302/01003
Abstract: A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X1NNNX2X3NYQX4X5X6X7X8, wherein the X1 and X8 mean a pair of opposite charged amino acid residues, and the X2, X3, X4, X5, X6, or X7 means an amino acid residue is described. A mixture for diminising a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.
Abstract translation: SBD的多糖 - 蛋白质结合模型和由X1NNNX2X3NYQX4X5X6X7X8组成的原纤维形成的14残基肽，其中X1和X8表示一对相对带电的氨基酸残基，X2，X3，X4，X5，X6或 X7表示氨基酸残基。 还提供了用于减少多糖的混合物，其包含至少两种淀粉结合结构域（SBD）和螺旋形式的多糖。 进一步描述提供寡糖的方法和淀粉样样原纤维的生产方法及其用途。
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公开(公告)号：US20100048880A1
公开(公告)日：2010-02-25
申请号：US12447848
申请日：2006-10-31
Applicant: Margaret Dah-Tsyr Chang , Ping-Chiang Lyu , Yuh-Ju Sun , Chia-Chin Sheu
Inventor： Margaret Dah-Tsyr Chang , Ping-Chiang Lyu , Yuh-Ju Sun , Chia-Chin Sheu
CPC classification number: C12N15/62 , C07K2319/20 , C12N9/2428
Abstract: The present invention relates to a starch binding domain, a recombinant protein and a complex thereof. The present invention also relates to a method for separating a recombinant protein comprising a starch binding domain of the present invention.
Abstract translation: 本发明涉及淀粉结合结构域，重组蛋白及其复合物。 本发明还涉及分离包含本发明的淀粉结合结构域的重组蛋白质的方法。
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5.发明申请POLYSACCHARIDE-PROTEIN BINDING MODEL AND NANO-FIBRIL FORMATION OF A STARCH BINDING DOMAIN 有权多糖 - 蛋白质结合模型和纳米纤维形成淀粉结合域公开(公告)号：US20090186369A1
公开(公告)日：2009-07-23
申请号：US12359035
申请日：2009-01-23
Applicant: Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
Inventor： Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
CPC classification number: C12N9/2428 , C07K7/08 , C07K2319/00 , C12Y302/01003
Abstract: The present invention relates to a polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X1NNNX2X3NYQX4X5X6X7X8, wherein the X1 and X8 mean a pair of opposite charged amino acid residues, and the X2, X3, X4, X5, X6, or X7 means an amino acid residue. The present invention also relates to a mixture for diminising a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form. The present invention further relates to a method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof.
Abstract translation: 本发明涉及SBD的多糖 - 蛋白结合模型和由X1NNNX2X3NYQX4X5X6X7X8组成的原纤维形成的14残基肽，其中X1和X8表示一对相对带电的氨基酸残基，X2，X3，X4， X5，X6或X7表示氨基酸残基。 本发明还涉及用于减少多糖的混合物，其包含至少两种淀粉结合结构域（SBD）和螺旋形式的多糖。 本发明还涉及提供寡糖的方法，以及淀粉样样原纤维的制造方法及其用途。
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6.发明授权Polysaccharide-protein binding model and nano-fibril formation of a starch binding domain 有权多糖 - 蛋白结合模型和淀粉结合结构域的纳米原纤维形成公开(公告)号：US08999688B2
公开(公告)日：2015-04-07
申请号：US13009650
申请日：2011-01-19
Applicant: Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
Inventor： Margaret Dah-Tsyr Chang , Yuh-Ju Sun , Ping-Chiang Lyu , Shu-Chuan Lin , Wei-I Chou
CPC classification number: C12N9/2428 , C07K7/08 , C07K2319/00 , C12Y302/01003
Abstract: A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X1NNNX2X3NYQX4X5X6X7X8, wherein the X1 and X8 mean a pair of opposite charged amino acid residues, and the X2, X3, X4, X5, X6, or X7 means an amino acid residue is described. A mixture for diminishing a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.
Abstract translation: SBD的多糖 - 蛋白质结合模型和由X1NNNX2X3NYQX4X5X6X7X8组成的原纤维形成的14残基肽，其中X1和X8表示一对相对带电的氨基酸残基，X2，X3，X4，X5，X6或 X7表示氨基酸残基。 还提供了用于减少多糖的混合物，其包含至少两种淀粉结合结构域（SBD）和螺旋形式的多糖。 进一步描述提供寡糖的方法和淀粉样样原纤维的生产方法及其用途。
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公开(公告)号：US20120225492A1
公开(公告)日：2012-09-06
申请号：US13355966
申请日：2012-01-23
Applicant: Margaret Dah-Tsyr Chang , Ping-Chiang Lyu , Yuh-Ju Sun , Chia-Chin Sheu
Inventor： Margaret Dah-Tsyr Chang , Ping-Chiang Lyu , Yuh-Ju Sun , Chia-Chin Sheu
IPC: G01N33/566
CPC classification number: C12N15/62 , C07K2319/20 , C12N9/2428
Abstract: The present invention provides a method for identifying starch binding sites of starch binding domain in CBM family. The CBM family is consisting of CBM20, CBM21, CBM25, CBM26, CBM34, and CBM41. The method further comprises predicting starch binding sites of starch binding domain in CBM family using the identified starch binding sites of starch binding domain with same topology.
Abstract translation: 本发明提供了一种用于鉴定CBM系列中淀粉结合结构域的淀粉结合位点的方法。 CBM系列由CBM20，CBM21，CBM25，CBM26，CBM34和CBM41组成。 该方法还包括使用具有相同拓扑结构的淀粉结合域的确定的淀粉结合位点预测CBM家族中淀粉结合结构域的淀粉结合位点。
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