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公开(公告)号：US08591841B2
公开(公告)日：2013-11-26
申请号：US13318691
申请日：2009-05-14
申请人： Yukako Asano , Tetsuro Miyamoto , Shigenori Togashi , Yoshishige Endo , Hidekazu Tsudome , Hajime Kato
发明人： Yukako Asano , Tetsuro Miyamoto , Shigenori Togashi , Yoshishige Endo , Hidekazu Tsudome , Hajime Kato
CPC分类号： B01J19/0093 , B01F5/0641 , B01F13/0059 , B01J2219/00783 , B01J2219/00867 , B01J2219/00889 , B01J2219/00891
摘要： In relation to a microreactor, and also a microreactor system applying the same therein, not producing any dead volume therein, and thereby achieving a high level of mixing properties even at a low solution flow rate and having a simple structure thereof, disclosed herein are a microreactor and microreactor system, comprising a channel for mixing up at least two (2) types of fluids, and thereby conducting mixing/reacting of fluids by conducting the mixing/reacting of the fluids at least one (1) time, i.e., being suitable for so-called a multi-step reaction.
摘要翻译： 关于微反应器以及其中应用其的微反应器系统，其中不产生任何死体积，从而即使在低溶液流速下实现高水平的混合特性并且具有简单的结构，这里公开了一种 微反应器和微反应器系统，其包括用于混合至少两种（2）类型的流体的通道，从而通过使流体的混合/反应进行混合/反应，至少一次（即）适合 用于所谓的多步反应。
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公开(公告)号：US08153070B2
公开(公告)日：2012-04-10
申请号：US12431011
申请日：2009-04-28
CPC分类号： B01F5/0471 , B01F13/0059 , B01J19/0093 , B01J2219/00783 , B01J2219/0086 , B01J2219/00889
摘要： A microreactor capable of reducing a pressure drop in an entire system includes a mixer 103 having a mixing channel for mixing two kinds of raw materials 101 and 102, and a reactor 109 having a reaction channel connected to the downstream side of the mixing channel to receive the mixture flowing out from the mixing channel and cause chemical reactions of the mixture inside the reaction channel. The reactor 109 a first reactor unit 107 having a large surface-to-volume (S-V) ratio of the reaction channel at an upstream side, and a second reactor unit 108 having a small S-V ratio of the reaction channel at a downstream.
摘要翻译： 能够减少整个系统的压力降的微反应器包括具有用于混合两种原料101和102的混合通道的混合器103和具有连接到混合通道的下游侧的反应通道的反应器109以接收 混合物从混合通道流出并引起混合物在反应通道内的化学反应。 反应器109具有上游侧的反应通道的表面体积比（S-V）大的第一反应器单元107和在下游具有反应通道的S-V比小的第二反应器单元108。
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公开(公告)号：US20120045370A1
公开(公告)日：2012-02-23
申请号：US13318691
申请日：2009-05-14
申请人： Yukako Asano , Tetsuro Miyamoto , Shigenori Togashi , Yoshishige Endo , Hidekazu Tsudome , Hajime Kato
发明人： Yukako Asano , Tetsuro Miyamoto , Shigenori Togashi , Yoshishige Endo , Hidekazu Tsudome , Hajime Kato
IPC分类号： B01J14/00
CPC分类号： B01J19/0093 , B01F5/0641 , B01F13/0059 , B01J2219/00783 , B01J2219/00867 , B01J2219/00889 , B01J2219/00891
摘要： In relation to a microreactor, and also a microreactor system applying the same therein, not producing any dead volume therein, and thereby achieving a high level of mixing properties even at a low solution flow rate and having a simple structure thereof, disclosed herein are a microreactor and microreactor system, comprising a channel for mixing up at least two (2) types of fluids, and thereby conducting mixing/reacting of fluids by conducting the mixing/reacting of the fluids at least one (1) time, i.e., being suitable for so-called a multi-step reaction.
摘要翻译： 关于微反应器以及其中应用其的微反应器系统，其中不产生任何死体积，从而即使在低溶液流速下实现高水平的混合特性并且具有简单的结构，这里公开了一种 微反应器和微反应器系统，其包括用于混合至少两种（2）类型的流体的通道，从而通过使流体的混合/反应进行混合/反应，至少一次（即）适合 用于所谓的多步反应。
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公开(公告)号：US20090269251A1
公开(公告)日：2009-10-29
申请号：US12431011
申请日：2009-04-28
IPC分类号： B01J19/00
CPC分类号： B01F5/0471 , B01F13/0059 , B01J19/0093 , B01J2219/00783 , B01J2219/0086 , B01J2219/00889
摘要： Disclosed herein is a microreactor capable of reducing a pressure drop in an entire system.The microreactor includes a mixer 103 having a mixing channel for mixing two kinds of raw materials 101 and 102, and a reactor 109 having a reaction channel connected to the downstream side of the mixing channel to receive the mixture flowing out from the mixing channel and cause chemical reactions of the mixture inside the reaction channel. The reactor 109 a first reactor unit 107 having a large surface-to-volume (S-V) ratio of the reaction channel at an upstream side, and a second reactor unit 108 having a small S-V ratio of the reaction channel at a downstream.
摘要翻译： 本文公开了一种能够减少整个系统中的压降的微反应器。 微反应器包括具有用于混合两种原料101和102的混合通道的混合器103和具有连接到混合通道的下游侧的反应通道的反应器109，以接收从混合通道流出的混合物，并引起 反应通道内混合物的化学反应。 反应器109具有上游侧的反应通道的表面体积比（S-V）大的第一反应器单元107和在下游具有反应通道的S-V比小的第二反应器单元108。
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5.发明申请公开(公告)号：US20080176330A1
公开(公告)日：2008-07-24
申请号：US11624397
申请日：2007-01-18
申请人： Yukako ASANO , Masashi Oda
发明人： Yukako ASANO , Masashi Oda
IPC分类号： G01N31/00
CPC分类号： G01M3/26 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00831 , B01J2219/00853 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00963
摘要： The present invention is to detect leakage of fluid from a channel in a microreactor certainly at an early stage. A chemical reactor has a microreactor with a pump for sending first, second solutions, and a channel for mixing and reacting the first, second solutions. The solution sending amount of the first, second solutions to be supplied to the microreactor is controlled by a pump controlling device. The microreactor has a first substrate with a channel and a second substrate to be bonded airtightly with the first substrate. A leak detecting channel is formed in the vicinity of the channel in the first substrate.
摘要翻译： 本发明是为了在早期阶段检测微反应器中的通道中的流体泄漏。 化学反应器具有微反应器，其具有用于发送第一溶液和第二溶液的泵，以及用于混合和反应第一溶液和第二溶液的通道。 供给微反应器的第一溶液的溶液送出量由泵控制装置控制。 微反应器具有带有通道的第一基板和与第一基板气密地接合的第二基板。 在第一基板中的通道附近形成泄漏检测通道。
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公开(公告)号：US20140050630A1
公开(公告)日：2014-02-20
申请号：US14114389
申请日：2011-05-13
申请人： Yukako Asano , Shigenori Togashi
发明人： Yukako Asano , Shigenori Togashi
CPC分类号： B01J19/0093 , B01J19/122 , B01J2219/00792 , B01J2219/00806 , B01J2219/00808 , B01J2219/00819 , B01J2219/00831 , B01J2219/00867 , B01J2219/00873 , B01J2219/00934 , B01J2219/00943
摘要： A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.
摘要翻译： 用于光反应的微反应器包括壳体上部，由允许透光的材料制成的盖板，由抑制光反射并具有高导热性的材料制成的流路板和壳体下部。 通过壳体上部和盖板的窗口将光照射到流路板的流路。 由允许透光的材料制成的盖板和由抑制光反射并具有高导热性的材料制成的流路板彼此焊接以形成一体。
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公开(公告)号：US09370760B2
公开(公告)日：2016-06-21
申请号：US14114389
申请日：2011-05-13
申请人： Yukako Asano , Shigenori Togashi
发明人： Yukako Asano , Shigenori Togashi
CPC分类号： B01J19/0093 , B01J19/122 , B01J2219/00792 , B01J2219/00806 , B01J2219/00808 , B01J2219/00819 , B01J2219/00831 , B01J2219/00867 , B01J2219/00873 , B01J2219/00934 , B01J2219/00943
摘要： A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.
摘要翻译： 用于光反应的微反应器包括壳体上部，由允许透光的材料制成的盖板，由抑制光反射并具有高导热性的材料制成的流路板和壳体下部。 通过壳体上部和盖板的窗口将光照射到流路板的流路。 由允许透光的材料制成的盖板和由抑制光反射并具有高导热性的材料制成的流路板彼此焊接以形成一体。
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公开(公告)号：US20080175768A1
公开(公告)日：2008-07-24
申请号：US11829147
申请日：2007-07-27
申请人： Tadashi Sano , Mio Suzuki , Yukako Asano , Shigenori Togashi , Tsutomu Kawamura , Tomofumi Shiraishi
发明人： Tadashi Sano , Mio Suzuki , Yukako Asano , Shigenori Togashi , Tsutomu Kawamura , Tomofumi Shiraishi
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00869 , B01J2219/00873 , B01J2219/00891
摘要： There is provided a reaction apparatus which is capable of keeping the pressure inside the reactor and is applicable to various fields. This reaction apparatus comprises: a raw material tank (2) for storing a raw material; a high-pressure pump (3) communicated with the raw material tank (2) and designed to deliver the raw material therefrom; a reactor (1) which is disposed on the downstream side of the high-pressure pump (3) and designed to be supplied with the raw material in a compressed state; a heating bath (11) for heating the reactor (1) to promote a reaction; and a product tank (7) for receiving and recovering a product; wherein the reaction apparatus is further equipped with an inlet port which is interposed between the heating bath (11) and the product tank (7), and with an injection pump (6) for injecting an injecting liquid through the inlet port, whereby a pressure of product flowing into the product tank (7) is enabled to be reduced by making use of the flow rate of the injecting liquid.
摘要翻译： 提供了能够保持反应器内的压力并适用于各种领域的反应装置。 该反应装置包括：原料罐（2），用于储存原料; 与原料罐（2）连通并设计成从原料罐（2）输送原料的高压泵（3） 反应器（1），其设置在所述高压泵（3）的下游侧并设计成以压缩状态供给所述原料; 用于加热反应器（1）以促进反应的加热浴（11） 和用于接收和回收产品的产品罐（7）; 其特征在于，所述反应装置还具有插入在所述加热槽（11）和所述产品罐（7）之间的入口端口，以及用于通过所述入口喷射注入液体的注入泵（6） 能够通过利用注射液的流量来减少流入产品罐（7）的产品。
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公开(公告)号：US20060210444A1
公开(公告)日：2006-09-21
申请号：US11375114
申请日：2006-03-15
IPC分类号： B01L3/00
CPC分类号： B01J19/0093 , B01F13/0059 , B01F13/0093 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00961 , B01J2219/00984 , B01J2219/00986 , B01J2219/00995 , F28D2021/0077
摘要： There is provided means for increasing a yield and a selectivity of objective substancean objective substance in a consecutive reaction. A substance manufacturing equipment for reacting a substance A and a substance B that can perform a consecutive reaction to produce a product of a first stage reaction as an objective substance, including: a microchannel; a mixing portion including a channel for introducing a solution containing the substance A into the microchannel and a channel for introducing a solution containing the substance B into the microchannel; and a temperature control equipment for controlling a temperature of a reaction system in the microchannel, wherein the temperature control equipment controls the temperature of the reaction system in the microchannel within a temperature range higher than a reaction temperature by a batch method and lower than a boiling point of the reaction system.
摘要翻译： 提供了在连续反应中提高目标物质的产率和选择性的方法。 一种使物质A和物质B反应的物质制造设备，其可以进行连续反应以产生作为目标物质的第一级反应的产物，包括：微通道; 混合部分，其包括用于将含有物质A的溶液引入微通道的通道和用于将含有物质B的溶液引入微通道的通道; 以及用于控制微通道中的反应系统的温度的温度控制设备，其中温度控制设备通过间歇法控制微通道内的反应体系在比反应温度高的温度范围内的温度，并且低于沸点 点反应体系。
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公开(公告)号：US08221686B2
公开(公告)日：2012-07-17
申请号：US12702872
申请日：2010-02-09
IPC分类号： B01J19/00
CPC分类号： B01J19/0093 , B01F11/0077 , B01F11/0094 , B01F11/0283 , B01F13/0059 , B01F15/00162 , B01F15/00207 , B01F15/065
摘要： A particle manufacturing device for manufacturing a particle by mixing a plural number of fluids, thereby manufacturing a particle, being uniform in the size or particle diameter thereof, with stability comprises a mixing channel portion, which is configured to mix the plural number of fluids therein, a residence channel portion, which is connected with the mixing channel portion in series, and in which the particles manufactured in the mixing channel portion reside, a sensor mechanism, which is configured to sense at least a condition of the residence channel portion, and an agitation giving mechanism, which is configured to give an agitation to the residence channel portion, upon basis of the condition, which is detected by the sensor mechanism.
摘要翻译： 用于通过混合多种流体制造颗粒的颗粒制造装置，由此制造尺寸或粒径均匀的颗粒，其稳定性包括混合通道部分，其被配置为将多个流体混合在其中 ，与混合通道部分串联连接并且其中在混合通道部分中制造的颗粒驻留的居住通道部分;传感器机构，其被构造成感测住住通道部分的至少条件;以及 基于由传感器机构检测到的状况，将搅拌给予机构配置成对居住通道部分进行搅拌。
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