利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

20 条记录 (耗时 0.013 秒)

    CHEMICAL SYNTHESIS DEVICE
    1.
    发明申请
    CHEMICAL SYNTHESIS DEVICE 审中-公开
    化学合成装置

    公开(公告)号：US20080081005A1

    公开(公告)日：2008-04-03

    申请号：US11835457

    申请日：2007-08-08

    申请人： Mio SUZUKI ,  Shigenori TOGASHI ,  Tetsuro MIYAMOTO ,  Tadashi SANO

    发明人： Mio SUZUKI ,  Shigenori TOGASHI ,  Tetsuro MIYAMOTO ,  Tadashi SANO

    IPC分类号： G05D7/00

    CPC分类号： B01J19/0093 ,  B01J19/0006 ,  B01J2219/00191 ,  B01J2219/00869 ,  B01J2219/0095 ,  B01J2219/00961

    摘要： An object of the present invention is to increase the volume of production even with the use of a microreactor, and to improve the quality of reaction products. A chemical synthesis device with a microreactor having a microchannel includes a plurality of microreactors arranged in parallel; a raw material tank that stores a raw material; a pump that delivers the raw material; an inlet solenoid valve and an outlet solenoid valve disposed at the inlet and outlet sides, respectively, of each of the microreactor; a temperature sensor that detects the temperature in the microreactor; and a pressure gage installed at the outlet side of the pump. The chemical synthesis device controls, in connection with values detected by the temperature sensor and the pressure gage, the opening and closing of the inlet solenoid valve and the outlet solenoid valve as well as a rate of flow from the pump.

    摘要翻译： 本发明的目的在于，通过使用微反应器来增加生产量，提高反应产物的质量。 具有微通道的微反应器的化学合成装置包括平行布置的多个微反应器; 储存原料的原料罐; 提供原料的泵; 分别设置在每个微反应器的入口侧和出口侧的入口电磁阀和出口电磁阀; 检测微反应器中的温度的温度传感器; 以及安装在泵出口侧的压力表。 化学合成装置与温度传感器和压力表检测到的值相关联，控制入口电磁阀和出口电磁阀的打开和关闭以及从泵的流量。

    Measuring apparatus for interaction of biomolecule
    2.
    发明申请
    Measuring apparatus for interaction of biomolecule 失效
    生物分子相互作用的测量装置

    公开(公告)号：US20070238162A1

    公开(公告)日：2007-10-11

    申请号：US11214948

    申请日：2005-08-31

    申请人： Tetsuro Miyamoto ,  Hiroyuki Takei ,  Shigenori Togashi ,  Ryo Miyake

    发明人： Tetsuro Miyamoto ,  Hiroyuki Takei ,  Shigenori Togashi ,  Ryo Miyake

    IPC分类号： C12M3/00

    CPC分类号： G01N21/253 ,  G01N21/553 ,  G01N35/028 ,  G01N35/1095

    摘要： In a measuring apparatus for biomolecule interaction, a fine particle sensor surface is dipped in a buffer solution in a reaction vessel to conduct spectral measurement by way of optical fibers. The buffer solution in the reaction vessel is made to enter an upper reaction vessel and discharged from a flow channel. Air is injected from a flow channel to inject a specimen from the discharge port to the reaction vessel. Then the specimen is sucked into the reaction vessel and brought into contact with the sensor surface where a ligand and an analyte in the specimen are bonded. Bonding is measured by a spectrophotometer through the optical fibers. A buffer solution is injected from the injection flow channel into the reaction vessel and the specimen is discharged out of the flow channel. The dissociation process in which the biomolecules are dissociated along with lowering of the concentration is measured.

    摘要翻译： 在用于生物分子相互作用的测量装置中，将细颗粒传感器表面浸入反应容器中的缓冲溶液中以通过光纤进行光谱测量。 将反应容器中的缓冲溶液进入上反应容器并从流动通道排出。 空气从流动通道注入，将样品从排放口注入反应容器。 然后将样品吸入反应容器中，并与样品中的配体和分析物结合的传感器表面接触。 通过分光光度计通过光纤测量粘合。 将缓冲溶液从注射流通道注入反应容器中，并将样品从流动通道排出。 测量其中生物分子随浓度降低而解离的解离过程。

    Optical biosensor for biomolecular interaction analysis
    3.
    发明申请
    Optical biosensor for biomolecular interaction analysis 失效
    光生物传感器用于生物分子相互作用分析

    公开(公告)号：US20060269966A1

    公开(公告)日：2006-11-30

    申请号：US11441076

    申请日：2006-05-26

    申请人： Tetsuro Miyamoto ,  Mami Hakari ,  Shigenori Togashi

    发明人： Tetsuro Miyamoto ,  Mami Hakari ,  Shigenori Togashi

    IPC分类号： G01N33/53 ,  C12M1/34

    CPC分类号： G01N21/554 ,  G01N21/274 ,  G01N21/314 ,  G01N2021/258 ,  G01N2021/3148

    摘要： Biomolecular and other interactions are analyzed with a simpler construction. A biotic sample is fixed to noble metal nanoparticles, and light is irradiated from a light source to the noble metal nanoparticles through an optical fiber. Light obtained after reflection of the irradiated light by the noble metal nanoparticles is introduced to one or more optical detecting units through another optical fiber. The optical detecting unit(s) separately measure the intensity of the input light in a second band including a maximum absorption wavelength, a first band covering a longer wavelength range than the range covered by the second band, and a third band covering a shorter wavelength range than the range covered by the second band.

    摘要翻译： 用更简单的结构分析生物分子和其他相互作用。 将生物样品固定在贵金属纳米粒子上，通过光纤将光从光源照射到贵金属纳米粒子上。 通过贵金属纳米颗粒反射照射光后获得的光通过另一光纤被引入一个或多个光学检测单元。 光学检测单元分别测量包括最大吸收波长的第二波段中的输入光的强度，覆盖比由第二波段覆盖的范围更长的波长范围的第一波段和覆盖较短波长的第三波段 范围超过第二频带覆盖的范围。

    Measuring apparatus for interaction of biomolecule
    5.
    发明授权
    Measuring apparatus for interaction of biomolecule 失效
    生物分子相互作用的测量装置

    公开(公告)号：US07629166B2

    公开(公告)日：2009-12-08

    申请号：US11214948

    申请日：2005-08-31

    申请人： Tetsuro Miyamoto ,  Hiroyuki Takei ,  Shigenori Togashi ,  Ryo Miyake

    发明人： Tetsuro Miyamoto ,  Hiroyuki Takei ,  Shigenori Togashi ,  Ryo Miyake

    IPC分类号： C12M1/34

    CPC分类号： G01N21/253 ,  G01N21/553 ,  G01N35/028 ,  G01N35/1095

    摘要： In a measuring apparatus for biomolecule interaction, a fine particle sensor surface is dipped in a buffer solution in a reaction vessel to conduct spectral measurement by way of optical fibers. The buffer solution in the reaction vessel is made to enter an upper reaction vessel and discharged from a flow channel. Air is injected from a flow channel to inject a specimen from the discharge port to the reaction vessel. Then the specimen is sucked into the reaction vessel and brought into contact with the sensor surface where a ligand and an analyte in the specimen are bonded. Bonding is measured by a spectrophotometer through the optical fibers. A buffer solution is injected from the injection flow channel into the reaction vessel and the specimen is discharged out of the flow channel. The dissociation process in which the biomolecules are dissociated along with lowering of the concentration is measured.

    摘要翻译： 在用于生物分子相互作用的测量装置中，将细颗粒传感器表面浸入反应容器中的缓冲溶液中以通过光纤进行光谱测量。 将反应容器中的缓冲溶液进入上反应容器并从流动通道排出。 空气从流动通道注入，将样品从排放口注入反应容器。 然后将样品吸入反应容器中，并与样品中的配体和分析物结合的传感器表面接触。 通过分光光度计通过光纤测量粘合。 将缓冲溶液从注射流通道注入反应容器中，并将样品从流动通道排出。 测量其中生物分子随浓度降低而解离的解离过程。

    MICROORGANISM SEPARATION SYSTEM
    6.
    发明申请
    MICROORGANISM SEPARATION SYSTEM 审中-公开
    微生物分离系统

    公开(公告)号：US20080098092A1

    公开(公告)日：2008-04-24

    申请号：US11755944

    申请日：2007-05-31

    申请人： Tadashi Sano ,  Yasuhiko Sasaki ,  Hajime Ikuta ,  Kazuichi Isaka ,  Tatsuo Sumino ,  Shigenori Togashi ,  Tetsuro Miyamoto

    发明人： Tadashi Sano ,  Yasuhiko Sasaki ,  Hajime Ikuta ,  Kazuichi Isaka ,  Tatsuo Sumino ,  Shigenori Togashi ,  Tetsuro Miyamoto

    IPC分类号： G06F15/16 ,  C12M1/00

    CPC分类号： C12M47/02 ,  C12M47/04

    摘要： A microorganism separation system comprising a sample solution container 34 containing microorganisms, a separator 1, and a receiver 47, designed to separate microorganisms from the sample solution; further comprising a microorganism detection sensor and a plate 49 which has a plurality of receivers 47 connected to each other and an identification indicator, wherein when the microorganism detection sensor judges that a microorganism has passed, supply of the sample solution is stopped, the detected microorganism is discharged together with the sample solution, and then the solution starts to be injected into the receiver; and, the number of times microorganisms are detected during the time period from the start of the injection to the end is recognized as separation quantity; and then as separation information, the separation quantity, number for a receiver 47 into which a microorganism was injected for each identification indicator, signal waveform sent from the microorganism detection sensor at the separation, date and temperature are stored.

    摘要翻译： 一种微生物分离系统，包括含有微生物的样品溶液容器34，分离器1和接收器47，设计用于将微生物与样品溶液分离; 进一步包括微生物检测传感器和板49，其具有彼此连接的多个接收器47和识别指示器，其中当微生物检测传感器判断微生物已经通过时，停止供应样品溶液，检测到的微生物 与样品溶液一起放出，然后溶液开始注入接收器; 并且在从注射开始到结束的时间段期间检测到微生物的次数被识别为分离量; 然后作为分离信息，存储分离量，针对每个识别指示符注入微生物的接收器47的数量，在分离，日期和温度从微生物检测传感器发送的信号波形。

    Molecular interaction detector and molecule recovery device using the same
    7.
    发明申请
    Molecular interaction detector and molecule recovery device using the same 审中-公开
    分子相互作用检测器和分子回收装置使用相同

    公开(公告)号：US20060263243A1

    公开(公告)日：2006-11-23

    申请号：US11437701

    申请日：2006-05-22

    申请人： Mami Hakari ,  Tetsuro Miyamoto ,  Shigenori Togashi

    发明人： Mami Hakari ,  Tetsuro Miyamoto ,  Shigenori Togashi

    IPC分类号： G01N31/22

    CPC分类号： G01N21/31

    摘要： In a molecular interaction detector, a noble-metal free-electron thin film is formed on a substrate. Styrene-made nanoparticles are adsorbed onto the thin film surface. Another noble-metal free-electron thin film is formed on upper-half surfaces of the nanoparticles and is modified by an organic linker molecule. The organic linker molecule has a linear or branched chemical structure including a functional group capable of being fixed to the surface of the noble-metal free-electron thin film with a linear chain made of 1 to 5 atoms. A detergent is used in a mobile phase. Deposition of materials having no relation with the measurement onto a sensor can be avoided in the molecular interaction detector.

    摘要翻译： 在分子相互作用检测器中，在基板上形成贵金属自由电子薄膜。 苯乙烯制造的纳米颗粒被吸附到薄膜表面上。 另外的贵金属自由电子薄膜形成在纳米颗粒的上半部表面，并被有机连接分子修饰。 有机连接分子具有直链或支链化学结构，其包括能够用1-5个原子的直链固定在贵金属自由电子薄膜的表面上的官能团。 在流动相中使用洗涤剂。 可以在分子相互作用检测器中避免将与测量无关的材料沉积到传感器上。

    Microreactor
    9.
    发明授权
    Microreactor 有权
    微反应器

    公开(公告)号：US08153070B2

    公开(公告)日：2012-04-10

    申请号：US12431011

    申请日：2009-04-28

    申请人： Yukako Asano ,  Tetsuro Miyamoto ,  Hajime Katou ,  Shigenori Togashi

    发明人： Yukako Asano ,  Tetsuro Miyamoto ,  Hajime Katou ,  Shigenori Togashi

    IPC分类号： B01J19/00 ,  B01J8/00 ,  B01J8/04 ,  B01J10/00

    CPC分类号： B01F5/0471 ,  B01F13/0059 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/0086 ,  B01J2219/00889

    摘要： A microreactor capable of reducing a pressure drop in an entire system includes a mixer 103 having a mixing channel for mixing two kinds of raw materials 101 and 102, and a reactor 109 having a reaction channel connected to the downstream side of the mixing channel to receive the mixture flowing out from the mixing channel and cause chemical reactions of the mixture inside the reaction channel. The reactor 109 a first reactor unit 107 having a large surface-to-volume (S-V) ratio of the reaction channel at an upstream side, and a second reactor unit 108 having a small S-V ratio of the reaction channel at a downstream.

    摘要翻译： 能够减少整个系统的压力降的微反应器包括具有用于混合两种原料101和102的混合通道的混合器103和具有连接到混合通道的下游侧的反应通道的反应器109以接收 混合物从混合通道流出并引起混合物在反应通道内的化学反应。 反应器109具有上游侧的反应通道的表面体积比（S-V）大的第一反应器单元107和在下游具有反应通道的S-V比小的第二反应器单元108。