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    Spray freeze dried liposomal ciprofloxacin powder aerosol drug delivery
    1.
    发明申请
    Spray freeze dried liposomal ciprofloxacin powder aerosol drug delivery 审中-公开
    喷雾冷冻干燥脂质体环丙沙星粉末气雾剂药物输送

    公开(公告)号：US20060280691A1

    公开(公告)日：2006-12-14

    申请号：US11445347

    申请日：2006-06-02

    申请人： Zhaolin Wang ,  Helena Orszanska ,  Warren Finlay

    发明人： Zhaolin Wang ,  Helena Orszanska ,  Warren Finlay

    IPC分类号： A61K9/127 ,  A61K9/14 ,  A61L9/04

    CPC分类号： A61K9/0075 ,  A61K9/127 ,  A61K9/1617

    摘要： A powder for inhalatory aerosol delivery, the powder having: spray freeze dried liposome particles with a biologically active agent, such as an antibiotic, encapsulated within a phospholipid, and a method of producing a powder for inhalatory aerosol delivery, the method including the steps of: mixing a biologically active agent with a phospholipid to form a liquid liposome suspension; and spray freeze drying the liposome suspension to form particles of powder.

    摘要翻译： 一种用于吸入气雾剂输送的粉末，该粉末具有：具有包封在磷脂内的生物活性剂如抗生素的喷雾冷冻干燥脂质体颗粒，以及生产用于吸入性气雾剂递送的粉末的方法，所述方法包括以下步骤： ：将生物活性剂与磷脂混合以形成液体脂质体悬浮液; 并喷雾冷冻干燥脂质体悬浮液以形成粉末颗粒。

    Heat exchanger using non-pure water for steam generation
    2.
    发明授权
    Heat exchanger using non-pure water for steam generation 有权

    公开(公告)号：US11149940B2

    公开(公告)日：2021-10-19

    申请号：US15656450

    申请日：2017-07-21

    申请人： Greg Naterer ,  Zhaolin Wang ,  Edward Secnik

    发明人： Greg Naterer ,  Zhaolin Wang ,  Edward Secnik

    IPC分类号： F22B1/06 ,  C01B3/08 ,  C01B13/02 ,  F22B27/16 ,  F28D3/02 ,  F28D7/10 ,  F28D21/00 ,  C02F1/16 ,  B01D1/00 ,  C01B3/04 ,  F22B37/26 ,  C02F1/00

    摘要： A process and a device are described for producing high purity and high temperature steam from non-pure water which may be used in a variety of industrial processes that involve high temperature heat applications. The process and device may be used with technologies that generate steam using a variety of heat sources, such as, for example industrial furnaces, petrochemical plants, and emissions from incinerators. Of particular interest is the application in a thermochemical hydrogen production cycle such as the Cu—Cl Cycle. Non-pure water is used as the feedstock in the thermochemical hydrogen production cycle, with no need to adopt additional and conventional water pre-treatment and purification processes. The non-pure water may be selected from brackish water, saline water, seawater, used water, effluent treated water, tailings water, and other forms of water that is generally believed to be unusable as a direct feedstock of industrial processes. The direct usage of this water can significantly reduce water supply costs.

    Production of hydrogen from water using a thermochemical copper-chlorine cycle
    3.
    发明授权
    Production of hydrogen from water using a thermochemical copper-chlorine cycle 有权
    使用热化学铜 - 氯循环从水生产氢气

    公开(公告)号：US08628725B2

    公开(公告)日：2014-01-14

    申请号：US12292722

    申请日：2008-11-25

    申请人： Kamiel Samy Gabriel ,  Zhaolin Wang ,  Greg Naterer

    发明人： Kamiel Samy Gabriel ,  Zhaolin Wang ,  Greg Naterer

    IPC分类号： B01J8/22 ,  C25C1/12

    CPC分类号： B01J10/005 ,  B01J7/00 ,  B01J8/002 ,  B01J8/003 ,  B01J8/0453 ,  B01J8/0496 ,  B01J2208/00752 ,  B01J2219/00006 ,  C01B3/068 ,  C01B13/0207 ,  C25C1/12 ,  Y02E60/36

    摘要： A system for producing hydrogen gas from water decomposition using a thermochemical CuCl cycle, the improvement comprising the use of an insulated hydrogen production reactor comprising a reaction chamber and a separation chamber; the reaction chamber having a hydrogen chloride gas inlet and a solid copper inlet; one or more levels provided in the reaction chamber, the number of which is dependant on production scale and pressure drop; each level comprising a perforated plate with associated filter media, the perforations of the plate and media being of decreasing size from top to bottom of the reaction chamber, and being sized to permit downward flow of the hydrogen gas and molten CuCl products, as well as the HCL gas reactant, and to prevent entrainment of solid copper in the molten CuCl; the separation chamber being located below the reaction chamber and being of greater cross section than the reaction chamber and comprising a first hydrogen removal and entrained copper removal zone and a second molten CuCl removal zone; removal of the reaction products being controlled so as to substantially decrease the amount of entrained copper in the molten CuCl; and the first zone having outlets for removal of hydrogen gas and entrained copper particles, with the second zone having an outlet for removal of molten CuCl.

    摘要翻译： 使用热化学CuCl循环从水分解产生氢气的系统，其改进包括使用包含反应室和分离室的绝热氢气生产反应器; 反应室具有氯化氢气体入口和固体铜入口; 在反应室中提供一个或多个水平，其数量取决于生产规模和压降; 每个级别包括具有相关过滤介质的多孔板，板和介质的穿孔从反应室的顶部到底部具有减小的尺寸，并且其尺寸允许氢气和熔融的CuCl产物向下流动，以及 HCL气体反应物，并防止在熔融的CuCl中夹带固体铜; 所述分离室位于所述反应室下方并且具有比所述反应室更大的横截面，并且包括第一除氢和夹带的铜去除区和第二熔融的CuCl去除区; 控制反应产物的去除以显着减少熔融的CuCl中夹带的铜的量; 并且第一区域具有用于除去氢气和夹带的铜颗粒的出口，其中第二区域具有用于除去熔融的CuCl的出口。

    Device and method for deagglomeration of powder for inhalation
    5.
    发明申请
    Device and method for deagglomeration of powder for inhalation 审中-公开
    用于吸入粉末解聚的装置和方法

    公开(公告)号：US20070125375A1

    公开(公告)日：2007-06-07

    申请号：US11476899

    申请日：2006-06-29

    申请人： Warren Finlay ,  Zhaolin Wang

    发明人： Warren Finlay ,  Zhaolin Wang

    IPC分类号： A61M15/00 ,  B65D83/06

    CPC分类号： A61M15/0086 ,  A61M11/003 ,  A61M15/0021 ,  A61M2202/064 ,  A61M2206/16

    摘要： A device and method for deagglomerating powder agglomerates for inhalation. The device includes an inlet connected to a chamber and to a powder source for supplying the chamber with powder agglomerates and a flow of gas that define a swirling fluid flow inside the chamber. The device also includes an outlet connected to the chamber for inhalation such that the swirling fluid flow in the chamber can exit from the chamber as a longitudinal fluid flow that is directed along a longitudinal axis of the outlet, and a secondary fluid flow that is directed away from the longitudinal axis of the outlet. A mesh in the outlet prevents powder agglomerates above a predetermined size from traversing the mesh, and reduces the secondary fluid flow relative to the longitudinal fluid flow exiting from the chamber to thereby reduce powder deposition in a mouth and throat of a user.

    摘要翻译： 用于吸入的粉末团块解聚集的装置和方法。 该装置包括连接到室的入口和用于向腔室供应粉末团聚体和在腔室内限定旋转流体流的气流的粉末源。 该装置还包括连接到腔室以用于吸入的出口，使得腔室内的旋流流体可以沿着沿着出口的纵向轴线引导的纵向流体流动而从腔室排出，并且引导的次级流体流 远离出口的纵向轴线。 出口中的网格防止超过预定尺寸的粉末团聚物穿过网，并且相对于从室离开的纵向流体流减少二次流体流动，从而减少用户口腔和喉部中的粉末沉积。

    Powder formation by atmospheric spray-freeze drying
    9.
    发明授权
    Powder formation by atmospheric spray-freeze drying 有权
    通过大气喷雾冷冻干燥形成粉末

    公开(公告)号：US07363726B2

    公开(公告)日：2008-04-29

    申请号：US11318864

    申请日：2005-12-28

    申请人： Zhaolin Wang ,  Warren H. Finlay

    发明人： Zhaolin Wang ,  Warren H. Finlay

    IPC分类号： F26B5/06

    CPC分类号： F26B5/06 ,  F26B13/30

    摘要： A method of manufacturing heat-sensitive pharmaceutical powder is disclosed. The original pharmaceutical substances are dissolved in a solution or suspended in a suspension, which is sprayed through an atomizing nozzle and frozen in a cold gas phase or liquid nitrogen atomized directly in the spray-freeze chamber or gas jacket at the same time (for cooling purposes). The particles are freeze-dried at roughly atmospheric pressure in a down-stream fluid flow with exit filter thereby to remove moisture entrapped on or inside the frozen particles. The system has applicability for forming other powders.

    摘要翻译： 公开了一种制造热敏药用粉末的方法。 将原始药物溶解在悬浮液中，悬浮在悬浮液中，该悬浮液通过雾化喷嘴喷雾并在冷气相或液氮中在冷冻室或气套中同时雾化（用于冷却 目的）。 颗粒在大气压下在具有出口过滤器的下游流体流中冷冻干燥，从而除去截留在冷冻颗粒上或内部的水分。 该系统适用于形成其他粉末。