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    Device and method for forming tires
    3.
    发明授权
    Device and method for forming tires 有权
    轮胎成型装置及方法

    公开(公告)号：US08225836B2

    公开(公告)日：2012-07-24

    申请号：US12267643

    申请日：2008-11-10

    Applicant: Zhiquan Zhang ,  Jianhao Zhang

    Inventor： Zhiquan Zhang ,  Jianhao Zhang

    IPC: B29D30/20

    CPC classification number: B29D30/20

    Abstract: Provided is a device for forming a special giant all-steel radial OTR tire in a continuous process, the device comprising a first base guide rail, a second base guide rail, a headstock, a main building drum, a belt housing, a belt drum and an overhead rail. The first base guide rail and the second base guide rail are parallel to each other. The overhead rail comprising a first traveling unit and a second traveling unit are disposed above the first base guide rail and the second base guide rail. A method for forming a special giant all-steel radial OTR tire in a continuous process is also provided.

    Abstract translation: 本发明提供一种用于在连续过程中形成特殊巨型全钢径向OTR轮胎的装置，该装置包括第一基座导轨，第二底座导轨，主轴箱，主构造鼓，皮带壳体，皮带鼓 和架空铁路。 第一基座导轨和第二基座导轨彼此平行。 包括第一行进单元和第二行进单元的架空轨道设置在第一基座导轨和第二基座导轨上方。 还提供了一种在连续过程中形成特殊巨型全钢径向OTR轮胎的方法。

    Inhibitors of NF-κB activity
    5.
    发明授权
    Inhibitors of NF-κB activity 有权
    NF-κB活性抑制剂

    公开(公告)号：US08691764B2

    公开(公告)日：2014-04-08

    申请号：US12593550

    申请日：2008-03-28

    Applicant: Zhiquan Zhang ,  Basil Rigas

    Inventor： Zhiquan Zhang ,  Basil Rigas

    IPC: A61K38/00 ,  A61P29/00 ,  C12N15/00 ,  C12N5/00 ,  C12N5/02 ,  A61P23/00 ,  A61P35/00

    CPC classification number: A61K38/1709 ,  A61K31/404 ,  A61K31/60 ,  A61K45/06 ,  A61K2300/00

    Abstract: The present invention provides a method for inhibiting NF-κB activity in a subject, the method comprising providing an agent capable of inducing expression of annexin 1, whereby said agent induces expression of annexin 1 and whereby said induced expression of annexin 1 inhibits NF-κB activity. Also provided are annexin 1 mimetics capable of binding to NF-κB and pharmaceutical compositions of such inducing and mimetic agents.

    Abstract translation: 本发明提供了抑制受试者的NF-κB活性的方法，所述方法包括提供能够诱导膜联蛋白1表达的药剂，由此所述药物诱导膜联蛋白1的表达，由此所述诱导的膜联蛋白1的表达抑制NF - ＆kgr; B活动。 还提供了能够结合NF-κB和这种诱导和模拟剂的药物组合物的膜联蛋白1模拟物。

    HYDRAULIC LOCKING MECHANISM FOR MULTIPLE EXTRUSION HEAD OF AN EXTRUDER
    7.
    发明申请
    HYDRAULIC LOCKING MECHANISM FOR MULTIPLE EXTRUSION HEAD OF AN EXTRUDER 有权
    挤压机多头挤压头液压闭锁机构

    公开(公告)号：US20110097435A1

    公开(公告)日：2011-04-28

    申请号：US12824258

    申请日：2010-06-28

    Applicant: Zhiquan ZHANG ,  Jianhao ZHANG

    Inventor： Zhiquan ZHANG ,  Jianhao ZHANG

    IPC: B29C47/08

    CPC classification number: B29C47/0822 ,  B29C47/0019 ,  B29C47/065 ,  B29C47/0808 ,  B29C47/14 ,  B29L2007/001 ,  B29L2009/00

    Abstract: A hydraulic locking mechanism for multiple extrusion heads of an extruder, has two Y-shaped clamping arms, six wedges, six pushing bars, six oil cylinder brackets, six oil cylinders, and six locking holes. A pair of locking holes is formed on both sides of an upper portion and a lower portion of the barrel and the extrusion head thereof, respectively. The wedge is disposed on inner wall of the locking hole, and a locking hole thereof has a sectional area gradually decreasing from the outside to the inside. The clamping arms are disposed on both sides of the barrel and the extrusion head via fastening devices. A through hole for the pushing bar is disposed on a branch of each of the clamping arm and corresponds to six locking holes. A piston rod of the oil cylinder is connected to a rear end of the pushing bar, the six oil cylinders and the six pushing bars are respectively fixed on six branches of the two clamping arms via six brackets of an oil cylinder. The pushing bar is capable of moving along the through hole for the pushing bar as being driven by the oil cylinder, and a front end thereof is inserted in the locking hole and penetrably disposed in the through hole for the pushing bar. A slant is formed on the outer side on a front end of the pushing bar.

    Abstract translation: 用于挤出机多个挤压头的液压锁定机构具有两个Y形夹紧臂，六个楔形件，六个推杆，六个油缸支架，六个油缸和六个锁定孔。 分别在筒体的上部和下部两侧分别形成一对锁定孔。 楔形件设置在锁定孔的内壁上，其锁定孔的截面积从外部向内侧逐渐减小。 夹紧臂通过紧固装置设置在筒的两侧和挤压头上。 用于推杆的通孔设置在每个夹持臂的分支上，并且对应于六个锁定孔。 油缸的活塞杆连接到推杆的后端，六个油缸和六个推杆分别通过油缸的六个支架固定在两个夹紧臂的六个分支上。 推杆能够沿着油压缸驱动的推杆的通孔移动，并且其前端插入锁定孔中并可穿透地设置在用于推杆的通孔中。 在推杆的前端的外侧形成倾斜。

    DEVICE AND METHOD FOR FORMING TIRES
    8.
    发明申请
    DEVICE AND METHOD FOR FORMING TIRES 有权
    用于形成轮胎的装置和方法

    公开(公告)号：US20090218036A1

    公开(公告)日：2009-09-03

    申请号：US12267643

    申请日：2008-11-10

    Applicant: Zhiquan ZHANG ,  Jianhao ZHANG

    Inventor： Zhiquan ZHANG ,  Jianhao ZHANG

    IPC: B29D30/08

    CPC classification number: B29D30/20

    Abstract: Provided is a device for forming a special giant all-steel radial OTR tire in a continuous process, the device comprising a first base guide rail, a second base guide rail, a headstock, a main building drum, a belt housing, a belt drum and an overhead rail. The first base guide rail and the second base guide rail are parallel to each other. The overhead rail comprising a first traveling unit and a second traveling unit are disposed above the first base guide rail and the second base guide rail. A method for forming a special giant all-steel radial OTR tire in a continuous process is also provided.

    Abstract translation: 本发明提供一种用于在连续过程中形成特殊巨型全钢径向OTR轮胎的装置，该装置包括第一基座导轨，第二底座导轨，主轴箱，主构造鼓，皮带壳体，皮带鼓 和架空铁路。 第一基座导轨和第二基座导轨彼此平行。 包括第一行进单元和第二行进单元的架空轨道设置在第一基座导轨和第二基座导轨上方。 还提供了一种在连续过程中形成特殊巨型全钢径向OTR轮胎的方法。

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