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公开(公告)号:US20220195420A1
公开(公告)日:2022-06-23
申请号:US17517282
申请日:2021-11-02
Applicant: 10x Genomics, Inc.
Inventor: Zahra Kamila Belhocine , Rajiv Bharadwaj , Christopher Hindson , Michael Schnall-Levin , Bill Kengli Lin , Anthony Makarewicz , Pranav Patel , Katherine Pfeiffer , Andrew D. Price , Mohammad Rahimi Lenji , Tobias Daniel Wheeler , Yifeng Yin
IPC: C12N15/10 , C12Q1/6806 , C12Q1/6869
Abstract: Methods and systems are provided for sample preparation techniques and sequencing of macromolecular constituents of cells and other biological materials.
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公开(公告)号:US20210372998A1
公开(公告)日:2021-12-02
申请号:US17209045
申请日:2021-03-22
Applicant: 10X Genomics, Inc.
Inventor: Zahra Kamila Belhocine , Jason Bell , Zachary Bent , Rajiv Bharadwaj , Christopher Hindson , Mohammad Rahimi Lenji , Bill Kengli Lin , Anthony Makarewicz , Geoffrey McDermott , Elliott Meer , Francesca Meschi , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Michael Schnall-Levin , Sarah Taylor , Jessica Michele Terry , Tobias Daniel Wheeler , Yifeng Yin , Xinying Zheng , Solongo Batjargal Ziraldo , Eswar Prasad Ramachandran Iyer , Luigi Jhon Alvarado Martinez
IPC: G01N33/532 , C07K14/74 , C12N15/85 , G01N33/543 , G01N33/548 , C12N15/10 , C12Q1/6804 , C12Q1/6806 , G01N33/50 , G01N33/53 , G01N33/58 , C12Q1/6818 , C12Q1/6827 , C12Q1/6881 , C12N15/11 , G01N33/569
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and antigen screening. Polynucleotide processing may be useful for a variety of applications. Antigen screening may comprise the use of one or more engineered cells. Engineered cells may be useful for characterizing one or more analytes including, for example, a polypeptide antigen.
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公开(公告)号:US20200002764A1
公开(公告)日:2020-01-02
申请号:US16443638
申请日:2019-06-17
Applicant: 10X Genomics, Inc.
Inventor: Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo , Stephane Claude Boutet , Sarah Taylor , Niranjan Srinivas
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6806
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
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公开(公告)号:US20180216162A1
公开(公告)日:2018-08-02
申请号:US15887947
申请日:2018-02-02
Applicant: 10X Genomics, Inc.
Inventor: Kamila Belhocine , Rajiv Bharadwaj , Christopher Hindson , Michael Schnall-Levin , Bill Lin , Anthony Makarewicz , Pranav Patel , Katherine Pfeiffer , Andrew D. Price , Mohammad Rahimi Lenji , Tobias Daniel Wheeler , Yifeng Yin
IPC: C12Q1/6806 , C12Q1/70
CPC classification number: C12N15/1065 , C12Q1/6806 , C12Q1/6869 , C12Q2563/149 , C12Q2563/179 , C12Q2531/113 , C12Q2535/122 , C12Q2563/159 , C12Q2565/625
Abstract: Methods and systems are provided for sample preparation techniques and sequencing of macromolecular constituents of cells and other biological materials.
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公开(公告)号:US20250146181A1
公开(公告)日:2025-05-08
申请号:US19016998
申请日:2025-01-10
Applicant: 10x Genomics, Inc.
Inventor: Zahra Kamila Belhocine , Rajiv Bharadwaj , Christopher Hindson , Michael Schnall-Levin , Bill Kengli Lin , Anthony Makarewicz , Pranav Patel , Katherine Pfeiffer , Andrew D. Price , Mohammad Rahimi Lenji , Tobias Daniel Wheeler , Yifeng Yin
IPC: C40B30/04 , C07K14/74 , C12N15/10 , C12N15/11 , C12N15/85 , C12Q1/6804 , C12Q1/6806 , C12Q1/6818 , C12Q1/6827 , C12Q1/6881 , C40B50/06 , C40B70/00 , G01N33/50 , G01N33/53 , G01N33/532 , G01N33/543 , G01N33/548 , G01N33/569 , G01N33/58
Abstract: Methods and systems are provided for sample preparation techniques and sequencing of macromolecular constituents of cells and other biological materials.
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公开(公告)号:US12264411B2
公开(公告)日:2025-04-01
申请号:US18593788
申请日:2024-03-01
Applicant: 10x Genomics, Inc.
Inventor: Zahra Kamila Belhocine , Rajiv Bharadwaj , Christopher Hindson , Michael Schnall-Levin , Bill Kengli Lin , Anthony Makarewicz , Pranav Patel , Katherine Pfeiffer , Andrew D. Price , Mohammad Rahimi Lenji , Tobias Wheeler , Yifeng Yin
IPC: C40B30/04 , C07K14/74 , C12N15/10 , C12N15/11 , C12N15/85 , C12Q1/6804 , C12Q1/6806 , C12Q1/6818 , C12Q1/6827 , C12Q1/6881 , C40B50/06 , G01N33/50 , G01N33/53 , G01N33/532 , G01N33/543 , G01N33/548 , G01N33/569 , G01N33/58 , C40B70/00
Abstract: Methods and systems are provided for sample preparation techniques and sequencing of macromolecular constituents of cells and other biological materials.
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公开(公告)号:US20250027150A1
公开(公告)日:2025-01-23
申请号:US18786209
申请日:2024-07-26
Applicant: 10x Genomics, Inc.
Inventor: Phillip Belgrader , Zachary Bent , Rajiv Bharadwaj , Vijay Kumar Sreenivasa Gopalan , Josephine Harada , Christopher Hindson , Mohammad Rahimi Lenji , Michael Ybarra Lucero , Geoffrey McDermott , Elliott Meer , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Serge Saxonov , John R. Stuelpnagel , Jessica Michele Terry , Tobias Daniel Wheeler , Indira Wu , Solongo Batjargal Ziraldo , Stephane Claude Boutet , Sarah Taylor , Niranjan Srinivas
IPC: C12Q1/6874 , C12Q1/6806 , C12Q1/683
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
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公开(公告)号:US20210102936A1
公开(公告)日:2021-04-08
申请号:US16897126
申请日:2020-06-09
Applicant: 10X Genomics, Inc.
Inventor: Zahra Kamila Belhocine , Jason Bell , Zachary Bent , Rajiv Bharadwaj , Christopher Hindson , Mohammad Rahimi Lenji , Bill Lin , Anthony Makarewicz , Geoffrey McDermott , Elliott Meer , Francesca Meschi , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Michael Schnall-Levin , Sarah Taylor , Jessica Michele Terry , Tobias Daniel Wheeler , Yifeng Yin , Xinying Zheng , Solongo Batjargal Ziraldo , Eswar Prasad Ramachandran Iyer , Luigi Jhon Alvarado Martinez
IPC: G01N33/532 , C07K14/74 , C12N15/85 , G01N33/543 , G01N33/548 , C12N15/10 , C12Q1/6804 , C12Q1/6806 , G01N33/50 , G01N33/53 , G01N33/58 , C12Q1/6818 , C12Q1/6827 , C12Q1/6881 , C12N15/11 , G01N33/569
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization from a single cell. Such polynucleotide processing may be useful for a variety of applications. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins) and chromatin (e.g., accessible chromatin).
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公开(公告)号:US20190383798A1
公开(公告)日:2019-12-19
申请号:US16375110
申请日:2019-04-04
Applicant: 10X Genomics, Inc.
Inventor: Kamila Belhocine , Jason Bell , Zachary Bent , Rajiv Bharadwaj , Christopher Hindson , Mohammad Rahimi Lenji , Bill Kengli Lin , Anthony Makarewicz , Geoffrey McDermott , Elliott Meer , Francesca Meschi , Tarjei Sigurd Mikkelsen , Christopher Joachim O'Keeffe , Katherine Pfeiffer , Andrew D. Price , Paul Ryvkin , Michael Schnall-Levin , Sarah Taylor , Jessica Michele Terry , Tobias Daniel Wheeler , Yifeng Yin , Xinying Zheng , Solongo Batjargal Ziraldo , Eswar Prasad Ramachandran Iyer , Luigi Jhon Alvarado Martinez
IPC: G01N33/50 , G01N33/543 , G01N33/53 , G01N33/569 , C12N15/10
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and antigen screening. Polynucleotide processing may be useful for a variety of applications. Antigen screening may comprise the use of one or more engineered cells. Engineered cells may be useful for characterizing one or more analytes including, for example, a polypeptide antigen.
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公开(公告)号:US10428326B2
公开(公告)日:2019-10-01
申请号:US15887947
申请日:2018-02-02
Applicant: 10X Genomics, Inc.
Inventor: Kamila Belhocine , Rajiv Bharadwaj , Christopher Hindson , Michael Schnall-Levin , Bill Lin , Anthony Makarewicz , Pranav Patel , Katherine Pfeiffer , Andrew D. Price , Mohammad Rahimi Lenji , Tobias Daniel Wheeler , Yifeng Yin
IPC: C12N15/10 , C12Q1/6806 , C12Q1/6869
Abstract: Methods and systems are provided for sample preparation techniques and sequencing of macromolecular constituents of cells and other biological materials.
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