公开(公告)号：US20240167939A1

公开(公告)日：2024-05-23

申请号：US18507648

申请日：2023-11-13

Applicant: 10x Genomics, Inc.

Inventor： Evan DeJARNETTE ,  Tyler DRAKE ,  Hendricus MARINDRA ,  Jack HERRERA ,  Eric EVJE ,  Alexander Post KINDWALL ,  David MORGAN

IPC: G01N21/03 ,  G01N21/75 ,  H05K7/20

CPC classification number: G01N21/0332 ,  G01N21/75 ,  H05K7/20281

Abstract: Various embodiments of the present disclosure disclose methods and systems for heat exchange in an opto-fluidic instrument. The opto-fluidic instrument includes a sample interface module (SIM), an illumination module, a camera module, and a reagent deck. A coolant from a coolant reservoir is directed into one or more of the modules so that heat exchange occurs at each module with the coolant. The heated coolant from the one or more modules flows to a radiator for cooling, for example, with fans flowing ambient air over the radiator, before the cooled coolant is returned to the coolant reservoir for subsequent use in cooling the modules.

公开(公告)号：US20240171833A1

公开(公告)日：2024-05-23

申请号：US18509584

申请日：2023-11-15

Applicant: 10x Genomics, Inc.

Inventor： David HOFFMAN ,  Denis PRISTINSKI ,  Evan DeJARNETTE ,  David MORGAN

IPC: H04N23/51 ,  H04N23/11 ,  H04N23/52 ,  H04N23/55 ,  H04N23/56

CPC classification number: H04N23/51 ,  H04N23/11 ,  H04N23/52 ,  H04N23/55 ,  H04N23/56

Abstract: An imaging system includes an optical mounting plate having an aperture disposed between a first portion and a second portion, an imaging sensor disposed on the first portion, an objective lens disposed on the second portion, and an illumination assembly arranged within the aperture and disposed between the imaging sensor and the objective lens. The imaging system includes a heat sink coupled to the illumination assembly and configured to transfer heat away from light sources of the illumination assembly via a working fluid that flows through the heat sink.