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公开(公告)号:US20220234382A1
公开(公告)日:2022-07-28
申请号:US17610498
申请日:2020-05-26
发明人: Kevin W. Gotrik , Scott J. Jones , Huiwen Tai , Joan M. Frankel , Robert R. Owings , Bhaskar V. Velamakanni , Jeanne M. Bruss , David J. Rowe , Matthew E. Sousa , Bradley L. Givot
摘要: A transfer article with a thickness of less than 3 micrometers includes a first acrylate layer that is releasable from a metal or doped semiconductor release layer at a release value of from 2 to 50 grams/inch. The article includes a functional layer overlaying the first acrylate layer. The functional layer includes at least one microfractured inorganic layer about 3 nanometers to about 200 nanometers thick, which has a plurality of toolmarks interspersed with cracks.
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公开(公告)号:US20160317395A1
公开(公告)日:2016-11-03
申请号:US15102472
申请日:2014-12-08
发明人: Bhaskar V. Velamakanni , Steven Yu
CPC分类号: A61K6/04 , A61C5/70 , A61C5/73 , A61C5/77 , A61C7/12 , A61C7/14 , A61C7/20 , A61C8/00 , A61C8/0013 , A61C8/0048 , A61C8/005 , A61C8/008 , A61C13/0001 , A61C13/0003 , A61K6/0002 , A61K6/0017 , A61K6/046
摘要: The present disclosure provides a metal based dental article and a method of forming the metal based dental article. The metal based dental article includes a base layer, a first coating on the base layer and a second coating on the first coating. The base layer is formed from a metal substrate selected from the group consisting of a stainless steel, a titanium alloy or a nickel titanium alloy. The first coating is formed from a metal selected from the group consisting of nickel, a nickel alloy, copper, a copper alloy, zinc, a zinc alloy, tin, a tin alloy, gold or a gold alloy, where one of the first coating or the surface of the base layer has a surface roughness (Ra) from 0.1 to 1.0 microns as measured according to ASTM B46.1-2009. The second coating is formed from a metal selected from the group consisting of rhodium, a rhodium alloy, ruthenium, a ruthenium alloy, cobalt, a cobalt alloy, palladium, or a palladium alloy. The second coating has a predetermined thickness that provides the metal based dental article with a matte finish and a whiteness, L*, of at least 80 of the CIELAB color system (L*, a*, B*). t,?
摘要翻译: 本公开提供了一种金属基牙科用品和形成金属基牙科用品的方法。 金属基牙科制品包括基底层,基底层上的第一涂层和第一涂层上的第二涂层。 基层由选自不锈钢,钛合金或镍钛合金的金属基材形成。 第一涂层由选自镍,镍合金,铜,铜合金,锌,锌合金,锡,锡合金,金或金合金的金属形成,其中第一涂层 或者根据ASTM B46.1-2009测量,基底层的表面具有0.1至1.0微米的表面粗糙度(Ra)。 第二涂层由选自铑,铑合金,钌,钌合金,钴,钴合金,钯或钯合金的金属形成。 第二涂层具有预定厚度,其为金属基牙科制品提供了CIELAB颜色系统(L *,a *,B *)的至少80的无光泽度和白度L *。 t,?
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公开(公告)号:US20130052146A1
公开(公告)日:2013-02-28
申请号:US13664452
申请日:2012-10-31
发明人: Jie Yang , Bhaskar V. Velamakanni , Sumita B. Mitra , Alphonsus V. Pocius , John J. Stofko, JR. , Jeremy M. Yarwood
IPC分类号: A61K8/41 , A61K8/43 , A61K8/49 , A61K8/81 , A61Q11/00 , A61K8/89 , A61K8/87 , A61K8/84 , C07C215/10 , C07C233/18 , A61K8/42 , A61K8/85
摘要: Dental compositions are provided comprising a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein n is an integer from about 2 to about 5.
摘要翻译: 提供牙科组合物,其包含式I化合物或其药学上可接受的盐:其中n为约2至约5的整数。
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公开(公告)号:US20230049504A1
公开(公告)日:2023-02-16
申请号:US17788013
申请日:2020-12-29
发明人: Bhaskar V. Velamakanni , Kevin W. Gotrik , Kevin T. Reddy , Scott J. Jones , Matthew S. Stay , Matthew R.D. Smith , Yizhong Wang , Mikhail L. Pekurovsky , Narina Y. Stepanova
摘要: A transfer article includes an acrylate layer releasable from a release layer including a metal layer, a metal oxide layer, or a doped semiconductor layer at a release value of from 2 to 50 grams/inch (0.8 to 20 g/cm). A functional layer overlies the acrylate layer, wherein the functional layer includes at least one layer of a functional material selected to provide at least one of a therapeutic, aesthetic or cosmetic benefit on a dental appliance in a mouth of a patient, and wherein the transfer article has a thickness of less than 3 micrometers. A pattern of a transfer material is on a major surface of the functional layer, wherein the transfer material includes an adhesion modifying material chosen from release materials and adhesives.
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公开(公告)号:US20230000596A1
公开(公告)日:2023-01-05
申请号:US17784752
申请日:2020-12-23
发明人: Bhaskar V. Velamakanni , Paul R. Klaiber , Richard P. Rusin , Yizhong Wang , Kevin T. Reddy , Matthew S. Stay , Matthew R.D. Smith , Jennifer J. Post
IPC分类号: A61C7/08 , B33Y10/00 , B33Y80/00 , B29C64/106 , B41M1/12 , B41M1/04 , B29C59/02 , B33Y40/20 , A61C19/06 , A61C5/00
摘要: A method for making a dental appliance configured to position at least one tooth of a patient includes printing a hardenable liquid resin composition on a major surface of a polymeric material to form a pattern thereon, wherein the hardenable liquid resin composition includes a glass ionomer, a resin modified glass ionomer, and mixtures and combinations thereof. A dental appliance is formed from the polymeric material that includes an arrangement of cavities configured to receive one or more teeth.
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公开(公告)号:US20210353387A1
公开(公告)日:2021-11-18
申请号:US17284540
申请日:2019-10-11
发明人: Bhaskar V. Velamakanni , Paul R. Klaiber , Richard P. Rusin , Daniel J. Skamser , Negus B. Adefris
摘要: A dental appliance is described, the dental appliance including a polymeric substrate with a plurality of cavities for receiving one or more teeth, an arrangement of engineered microstructures on the substrate wherein the engineered microstructures include a therapeutic agent. The microstructures may be three-dimensionally engineered on a polymeric film disposed on a major surface of the polymeric substrate, wherein the microstructures extend outwards from the surface. The microstructures also comprise a compound releasable from the three-dimensionally engineered microstructures over a predetermined patient wear time.
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公开(公告)号:US20220061961A1
公开(公告)日:2022-03-03
申请号:US17417851
申请日:2019-12-30
发明人: Richard Y. Liu , Daniel J. Skamser , Bhaskar V. Velamakanni , Nathaniel I. Lehn , Mitchell A. Hirsch , Lyudmila A. Pekurovsky
摘要: A dental appliance for positioning a patients teeth includes a polymeric shell with a plurality of cavities for receiving one or more teeth. The polymeric shell includes at least 3 alternating polymeric layers AB, wherein layer A includes a thermoplastic polymer A, layer B includes a thermoplastic polymer B, and the thermoplastic polymer B is different from the thermoplastic polymer A. Each of the thermoplastic polymers A and B have a flexural modulus of about 1.0 GPa to about 4.0 GPa; and each of the thermoplastic polymers A and B have a glass transition temperature (Tg) greater than about 40° C.
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公开(公告)号:US20210251724A1
公开(公告)日:2021-08-19
申请号:US17251873
申请日:2019-06-10
发明人: Bhaskar V. Velamakanni , Ta-Hua Yu , Daniel J. Skamser , Narina Y. Stepanova , Mitchell A. Hirsch , Junkang J. Liu , Carola A. Carrera Vidal
摘要: A dental appliance includes a polymeric shell with a first major surface having a plurality of cavities for receiving one or more teeth, and a layer of a metal oxide MOx on the first major surface.
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公开(公告)号:US08647608B2
公开(公告)日:2014-02-11
申请号:US13664452
申请日:2012-10-31
发明人: Jie Yang , Bhaskar V. Velamakanni , Sumita B. Mitra , Alphonsus V. Pocius , John J. Stofko, Jr. , Jeremy M. Yarwood
IPC分类号: A61K8/41 , A61K8/42 , A61K8/85 , A61K8/87 , A61K8/89 , A61Q11/00 , C07C215/10 , C07C233/18
摘要: Dental compositions are provided comprising a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein n is an integer from about 2 to about 5.
摘要翻译: 提供牙科组合物,其包含式I化合物或其药学上可接受的盐:其中n为约2至约5的整数。
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公开(公告)号:US11999188B2
公开(公告)日:2024-06-04
申请号:US17610498
申请日:2020-05-26
发明人: Kevin W. Gotrik , Scott J. Jones , Huiwen Tai , Joan M. Frankel , Robert R. Owings , Bhaskar V. Velamakanni , Jeanne M. Bruss , David J. Rowe , Matthew E. Sousa , Bradley L. Givot
CPC分类号: B44C1/1708 , C23C14/5886
摘要: A transfer article with a thickness of less than 3 micrometers includes a first acrylate layer that is releasable from a metal or doped semiconductor release layer at a release value of from 2 to 50 grams/inch. The article includes a functional layer overlaying the first acrylate layer. The functional layer includes at least one microfractured inorganic layer about 3 nanometers to about 200 nanometers thick, which has a plurality of toolmarks interspersed with cracks.
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