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公开(公告)号：US10059977B2
公开(公告)日：2018-08-28
申请号：US15484781
申请日：2017-04-11
IPC分类号： C12Q1/22
摘要： Spore carriers suitable for use in biological indicators are described. The spore carriers include a substrate such as polymeric film or non-woven web with a hydrophilic nanostructured layer bonded to it. Spores are bonded to the nanostructured layer. Nanostructured layers including nanoparticles, such as acid-sintered silica nanoparticles are described. Biological indicators including such spore carriers are also described.
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公开(公告)号：US11951226B2
公开(公告)日：2024-04-09
申请号：US16949727
申请日：2020-11-12
IPC分类号： A61L2/28 , A61L2/20 , G01N21/77 , A61L101/44
CPC分类号： A61L2/28 , A61L2/206 , G01N21/77 , A61L2101/44
摘要： An ethylene oxide sterilization sensor, and method of use, wherein the sensor includes: a heat-shrinkable film; an acid-functional porous sorbent in thermal contact with the heat-shrinkable film; and an acid having a boiling point above 120° C. and a pKa of no greater than 2.5, wherein the acid is impregnated in or covalently attached to the porous sorbent.
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公开(公告)号：US20210154347A1
公开(公告)日：2021-05-27
申请号：US16949727
申请日：2020-11-12
摘要： An ethylene oxide sterilization sensor, and method of use, wherein the sensor includes: a heat-shrinkable film; an acid-functional porous sorbent in thermal contact with the heat-shrinkable film; and an acid having a boiling point above 120° C. and a pKa of no greater than 2.5, wherein the acid is impregnated in or covalently attached to the porous sorbent.
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公开(公告)号：US09650661B2
公开(公告)日：2017-05-16
申请号：US14891760
申请日：2014-05-13
摘要： Spore carriers suitable for use in biological indicators are described. The spore carriers include a substrate such as polymeric film or non-woven web with a hydrophilic nanostructured layer bonded to it. Spores are bonded to the nanostructured layer. Nanostructured layers including nanoparticles, such as acid-sintered silica nanoparticles are described. Biological indicators including such spore carriers are also described.
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公开(公告)号：US20220387653A1
公开(公告)日：2022-12-08
申请号：US17708475
申请日：2022-03-30
发明人： Michael W. Kobe , Michael S. Wendland , Richard C. Webb , Michael E. Hamerly , Daniel J. O'Neal , Kelvin J. Witcher , Dawud H. Tan , Daniel J. Zillig
摘要： The present disclosure provides an ethylene oxide sterilization sensor and method of use. The sensor includes: at least one thermal indicator component independently selected from an electronic thermal sensor, an irreversible temperature indicator, and a heat-shrinkable film; an acid-functional porous sorbent or an acid-functional nonwoven fibrous substrate in thermal contact with the at least one thermal indicator component; and an acid having a boiling point above 120° C. and a pKa of no greater than 2.5. The acid is impregnated in or covalently attached to the porous sorbent or is covalently attached to the nonwoven fibrous substrate. The sensor includes at least one of the electronic thermal sensor, the irreversible temperature indicator, or the acid-functional nonwoven fibrous substrate.
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公开(公告)号：US09575022B2
公开(公告)日：2017-02-21
申请号：US14429719
申请日：2013-10-02
发明人： G. Marco Bommarito , Myungchan Kang , Michael C. Palazzotto , Timothy J. Nies , Kelvin J. Witcher
CPC分类号： G01N27/023 , A47L15/4295 , A47L15/46 , A61L2/04 , A61L2/28 , A61L2202/17 , D06F39/002 , G01N27/021 , G01N27/22
摘要： An electronic indicator includes artificial soil and sensor. An electrical characteristic of the electronic indicator can vary due to a change in the volume of the artificial soil. In some embodiments, the electrical characteristic of the electronic indicator can be measured by an electrical characteristic reader and used to determine efficacy of a cleaning cycle.
摘要翻译： 电子指示器包括人造土壤和传感器。 电子指示器的电气特性可能由于人造土体积的变化而变化。 在一些实施例中，电子指示器的电特性可以由电特性读取器测量并用于确定清洁循环的功效。
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公开(公告)号：US20230047207A1
公开(公告)日：2023-02-16
申请号：US17758585
申请日：2021-01-14
摘要： The present disclosure is directed to self-contained biological indicators wherein a single type of indicator is capable of being used for various sterilization conditions, including sterilization with steam, hydrogen peroxide, and/or ethylene oxide. In some embodiments, a single type of biological indicator is capable of being used for different steam sterilization conditions having varied temperatures and sterilization cycles.
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公开(公告)号：US11421261B2
公开(公告)日：2022-08-23
申请号：US15733271
申请日：2018-12-17
发明人： Kelvin J. Witcher , Francois Ahimou , Naiyong Jing , Tonya D. Bonilla , Joshua D. Erickson , Hsi-Chou Liu , Andrew W. Vail
摘要： A method is provided. The method includes providing an article, the article including a nonwoven substrate having a copolymer grafted thereto, the copolymer including interpolymerized monomer units of a quaternary ammonium-containing ligand monomers; an amide monomer; an oxy monomer; and a coating on the nonwoven substrate, the coating including a plurality of test microorganisms, an enzyme or a second substrate; and contacting the article with a detection medium for a period of time.
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公开(公告)号：US20150233852A1
公开(公告)日：2015-08-20
申请号：US14429719
申请日：2013-10-02
发明人： G. Marco Bommarito , Myungchan Kang , Michael C. Palazzotto , Timothy J. Nies , Kelvin J. Witcher
CPC分类号： G01N27/023 , A47L15/4295 , A47L15/46 , A61L2/04 , A61L2/28 , A61L2202/17 , D06F39/002 , G01N27/021 , G01N27/22
摘要： An electronic indicator includes artificial soil and sensor. An electrical characteristic of the electronic indicator can vary due to a change in the volume of the artificial soil. In some embodiments, the electrical characteristic of the electronic indicator can be measured by an electrical characteristic reader and used to determine efficacy of a cleaning cycle.
摘要翻译： 电子指示器包括人造土壤和传感器。 电子指示器的电气特性可能由于人造土体积的变化而变化。 在一些实施例中，电子指示器的电特性可以由电特性读取器测量并用于确定清洁循环的功效。
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