公开(公告)号：US06902556B2

公开(公告)日：2005-06-07

申请号：US10162799

申请日：2002-06-05

申请人： Kevin V. Grimes ,  Jan Komtebedde ,  Daniel C. Rosenman ,  Hanson S. Gifford, III ,  Michi E. Garrison ,  Wesley D. Sterman ,  David M. Taylor ,  A. Adam Sharkawy ,  Pinaki Ray

发明人： Kevin V. Grimes ,  Jan Komtebedde ,  Daniel C. Rosenman ,  Hanson S. Gifford, III ,  Michi E. Garrison ,  Wesley D. Sterman ,  David M. Taylor ,  A. Adam Sharkawy ,  Pinaki Ray

IPC分类号： A61B17/00 ,  A61B17/02 ,  A61B17/34 ,  A61F2/958 ,  A61M31/00 ,  A61M29/00 ,  A61M37/00

CPC分类号： A61B17/3417 ,  A61B17/0206 ,  A61B17/3421 ,  A61B2017/00243 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1084 ,  A61M2210/127

摘要： A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula of the aortic occlusion catheter. In another aspect of the invention, an arterial cannula having a curved or angled distal portion. An introducer straightens the distal portion for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer is used to stabilize a discoid occluding member.

摘要翻译： 一种用于闭塞患者升主动脉的方法和装置，保持患者中含氧血液的循环并输送心脏停搏液以阻止患者的心脏。 主动脉闭塞导管具有用于闭塞升主动脉的阻塞构件。 主动脉闭塞导管穿过套管。 氧合血液的输送通过主动脉闭塞导管的插管来实现。 在本发明的另一方面，一种具有弯曲或成角度的远侧部分的动脉插管。 引导器拉直远端部分以引入患者体内。 在本发明的另一方面，使用开口网稳定剂来稳定盘状闭塞构件。

公开(公告)号：US06589206B1

公开(公告)日：2003-07-08

申请号：US09685383

申请日：2000-10-10

申请人： A. Adam Sharkawy ,  Wesley D. Sterman ,  David M. Taylor ,  Pinaki Ray

发明人： A. Adam Sharkawy ,  Wesley D. Sterman ,  David M. Taylor ,  Pinaki Ray

IPC分类号： A61M2900

CPC分类号： A61B17/3417 ,  A61B17/0206 ,  A61B17/3421 ,  A61B2017/00243 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1084 ,  A61M2210/127

摘要： A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula or the aortic occlusion catheter.

摘要翻译： 一种用于闭塞患者升主动脉的方法和装置，保持患者中充氧血液的循环并输送心脏停搏液以阻止患者的心脏。 主动脉闭塞导管具有用于闭塞升主动脉的阻塞构件。 主动脉闭塞导管穿过套管。 氧合血液的输送通过套管或主动脉闭塞导管完成。

公开(公告)号：US06592547B2

公开(公告)日：2003-07-15

申请号：US09235043

申请日：1999-01-21

申请人： Kevin V. Grimes ,  Jan Komtebedde ,  Daniel C. Rosenman ,  Hanson S. Gifford, III ,  Michi E. Garrison ,  Wesley D. Sterman ,  David M. Taylor ,  A. Adam Sharkawy ,  Pinaki Ray

发明人： Kevin V. Grimes ,  Jan Komtebedde ,  Daniel C. Rosenman ,  Hanson S. Gifford, III ,  Michi E. Garrison ,  Wesley D. Sterman ,  David M. Taylor ,  A. Adam Sharkawy ,  Pinaki Ray

IPC分类号： A61M2900

CPC分类号： A61B17/3417 ,  A61B17/0206 ,  A61B17/3421 ,  A61B2017/00243 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1084 ,  A61M2210/127

摘要： A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula or the aortic occlusion catheter. In another aspect of the invention, an arterial cannula having a curved or angled distal portion. An introducer straightens the distal portion for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer is used to stabilize a discoid occluding member.

公开(公告)号：US6159178A

公开(公告)日：2000-12-12

申请号：US12833

申请日：1998-01-23

申请人： A. Adam Sharkawy ,  Wesley D. Sterman ,  David M. Taylor ,  Pinaki Ray

发明人： A. Adam Sharkawy ,  Wesley D. Sterman ,  David M. Taylor ,  Pinaki Ray

IPC分类号： A61B17/00 ,  A61B17/02 ,  A61B17/34 ,  A61F2/958 ,  A61M29/00

CPC分类号： A61B17/3417 ,  A61M25/10 ,  A61B17/0206 ,  A61B17/3421 ,  A61B2017/00243 ,  A61M2025/1052 ,  A61M2025/1084 ,  A61M2210/127 ,  A61M25/1002

摘要： A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula or the aortic occlusion catheter.

公开(公告)号：US08512360B2

公开(公告)日：2013-08-20

申请号：US10778723

申请日：2004-02-13

申请人： A. Adam Sharkawy ,  Dean F. Carson ,  Darin C. Gittings ,  Keke J. Lepulu ,  Mark J. Foley ,  Wally S. Buch ,  Alan R. Rapacki

发明人： A. Adam Sharkawy ,  Dean F. Carson ,  Darin C. Gittings ,  Keke J. Lepulu ,  Mark J. Foley ,  Wally S. Buch ,  Alan R. Rapacki

IPC分类号： A61B17/08 ,  A61M5/00

CPC分类号： A61F2/94 ,  A61B17/11 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2018/00392 ,  A61F2/064 ,  A61F2/24 ,  A61F2/2493 ,  A61F2002/30079 ,  A61F2210/009 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2230/0058 ,  A61F2230/0076

摘要： Methods and devices for placing a target vessel in fluid communication with a source of blood and a target vessel. A conduit includes first portion adapted to be placed in fluid communication with a source of blood, such as a heart chamber, and a second portion adapted to be placed in fluid communication with a target vessel having a lumen, such as coronary artery. The first and second conduit portions are transverse to each other such that the conduit is generally T-shaped. The conduit lies on an exterior of the heart between the blood source and the target vessel and is configured to deliver blood in multiple directions into the lumen of the target vessel. For example, in an occluded coronary artery, blood flows both toward and away from the occlusion. The conduit may be flexible, rigid, collapsible or non-collapsible, and may be formed of synthetic vascular graft material, tissue, or a combination of the two. A conduit delivery device is disclosed for deploying the conduit in a target vessel and perfusing the vessel during such deployment.

摘要翻译： 用于放置目标血管与血液源和靶血管流体连通的方法和装置。 导管包括适于与诸如心脏腔的血液源流体连通的第一部分和适于与具有诸如冠状动脉的内腔的靶血管流体连通的第二部分。 第一和第二导管部分彼此横向，使得导管通常为T形。 导管位于血液源和目标血管之间的心脏外部，并被构造成将多个方向的血液输送到目标血管的内腔中。 例如，在闭塞的冠状动脉中，血液朝向和远离闭塞流动。 导管可以是柔性的，刚性的，可收缩的或不可折叠的，并且可以由合成的血管移植物材料，组织或两者的组合形成。 公开了一种导管输送装置，用于将导管部署在靶容器中并且在这种部署期间灌注容器。

公开(公告)号：US07137962B2

公开(公告)日：2006-11-21

申请号：US10011630

申请日：2001-10-22

申请人： Darin C. Gittings ,  A. Adam Sharkawy ,  Alan R. Rapacki ,  Gilbert S. Laroya

发明人： Darin C. Gittings ,  A. Adam Sharkawy ,  Alan R. Rapacki ,  Gilbert S. Laroya

IPC分类号： A61N5/00 ,  A61F2/04

CPC分类号： A61F2/94 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61F2/24 ,  A61F2/2493 ,  A61F2/82 ,  A61F2210/009 ,  A61F2220/0016 ,  A61F2230/005 ,  A61F2230/0091 ,  A61F2250/0007

摘要： Devices and methods utilized in performing transmyocardial coronary bypass include retractors used to engage and support myocardial tissue, and mechanisms for supporting coronary vessels so as to allow precise entry into a vessel lumen. In addition, various conduits are provided having a configuration that permits their positioning in a heart wall to place a coronary vessel in communication with a heart chamber.

公开(公告)号：US20080018016A1

公开(公告)日：2008-01-24

申请号：US11903680

申请日：2007-09-24

申请人： Alan Rapacki ,  Dean Carson ,  A. Adam Sharkawy

发明人： Alan Rapacki ,  Dean Carson ,  A. Adam Sharkawy

IPC分类号： B28B5/00

CPC分类号： B29C39/42 ,  A61F2/062 ,  A61F2240/001 ,  B29C39/025 ,  B29C39/10 ,  B29C45/1671 ,  B29K2083/005 ,  B29L2031/7534

摘要： Methods and devices for manufacturing a conduit for placing a target vessel in fluid communication with a source of blood, such as a heart chamber containing blood. The conduit includes first and second portion adapted to be placed in fluid communication with a heart chamber and a target vessel. The conduit lies on the exterior of the myocardium between the blood source and the target vessel and delivers blood in multiple directions within the lumen of the target vessel. The conduit, which may be formed of any suitable synthetic vascular graft material, is generally T-shaped with the leg having two free ends disposed in the target vessel, preferably being secured thereto via a suture-free attachment. The conduit comprises vascular graft material and may be manufactured various ways, such as molding a conduit from any suitable biocompatible material or fabricating a conduit from one or more pieces of vascular graft material.

摘要翻译： 用于制造用于放置目标血管与血液源（例如含有血液的心室）流体连通的导管的方法和装置。 导管包括适于与心脏腔室和靶容器流体连通的第一和第二部分。 导管位于血液源和目标血管之间的心肌外部，并在目标血管内腔内的多个方向输送血液。 可以由任何合适的合成血管移植材料形成的导管通常是T形的，腿部具有设置在靶容器中的两个自由端，优选通过无缝线的附件固定到其上。 导管包括血管移植材料，并且可以以各种方式制造，例如从任何合适的生物相容性材料模制导管或从一个或多个血管移植物材料制造导管。

公开(公告)号：US07232449B2

公开(公告)日：2007-06-19

申请号：US10388374

申请日：2003-03-12

申请人： A. Adam Sharkawy ,  J. Greg Stine ,  David H. Cole ,  Samuel Crews ,  Darin C. Gittings ,  Adam Kessler ,  Mark J. Foley

发明人： A. Adam Sharkawy ,  J. Greg Stine ,  David H. Cole ,  Samuel Crews ,  Darin C. Gittings ,  Adam Kessler ,  Mark J. Foley

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/0644 ,  A61B17/11 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/00876 ,  A61B2017/1107 ,  A61B2017/1132 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61B2018/00392 ,  A61F2/064 ,  A61F2/07 ,  A61F2/2493 ,  A61F2/848 ,  A61F2/852 ,  A61F2/90 ,  A61F2/94 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/30079 ,  A61F2002/821 ,  A61F2210/0076 ,  A61F2210/009 ,  A61F2220/005 ,  A61F2220/0066 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2250/006 ,  H01F41/026

摘要： Anastomotic components may be attached to hollow bodies or vessels by magnetic or mechanical force to create an anastomosis, form a port in a vessel, or repair a diseased vessel lumen. Anastomoses are created by coupling a first connection to an end of a vessel and then attracting it to a second connector secured to the side wall of another vessel. The connection between the first and second connectors may be solidly magnetic, solely mechanical, or a combination thereof. Also disclosed are methods and devices for treating diseased vessel lumens, for example abdominal aortic aneurysm. A plurality of docking members is attached to the vessel at solicited positions, and then one or more grafts is secured to the docking members in any suitable manner.

公开(公告)号：US06808498B2

公开(公告)日：2004-10-26

申请号：US09170793

申请日：1998-10-13

申请人： Gilbert S. Laroya ,  A. Adam Sharkawy ,  Mark J. Foley

发明人： Gilbert S. Laroya ,  A. Adam Sharkawy ,  Mark J. Foley

IPC分类号： A61B500

CPC分类号： A61F2/24 ,  A61B17/3415 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2018/00392 ,  A61F2/2493 ,  A61F2/94 ,  A61F2002/30079 ,  A61F2210/009 ,  A61M25/01

摘要： A guide member positioned through a coronary vessel and the wall of the heart provides access to a heart chamber. A first end of the guide member is passed through the coronary vessel and the heart wall into the heart chamber, and then is passed back out of the heart chamber. The end of the guide member may then be used to deliver devices into the heart chamber to carry out various medical procedures. A conduit delivery system is coupled to the end of the guide member and is delivered into the heart chamber and then used to place a conduit in the heart wall to communicate the coronary vessel with the heart chamber.

公开(公告)号：US06635214B2

公开(公告)日：2003-10-21

申请号：US09394119

申请日：1999-09-10

申请人： Alan R. Rapacki ,  Dean F. Carson ,  A. Adam Sharkawy

发明人： Alan R. Rapacki ,  Dean F. Carson ,  A. Adam Sharkawy

IPC分类号： B29C3902

CPC分类号： A61F2/2493 ,  A61B2017/00252 ,  A61F2/064 ,  B29C41/14 ,  B29C45/14598 ,  B29C45/261 ,  B29C66/857 ,  B29L2023/007 ,  B29L2031/7534 ,  B29C65/00

摘要： Methods and devices for manufacturing a conduit for placing a target vessel in fluid communication with a source of blood, such as a heart chamber containing blood. The conduit includes first and second portion adapted to be placed in fluid communication with a heart chamber and a target vessel. The conduit lies on the exterior of the myocardium between the blood source and the target vessel and delivers blood in multiple directions within the lumen of the target vessel. The conduit, which may be formed of any suitable synthetic vascular graft material, is generally T-shaped with the leg having two free ends disposed in the target vessel, preferably being secured thereto via a suture-free attachment. The conduit comprises vascular graft material and may be manufactured various ways, such as molding a conduit from any suitable biocompatible material or fabricating a conduit from one or more pieces of vascular graft material.

摘要翻译： 用于制造用于放置目标血管与血液源（例如含有血液的心室）流体连通的导管的方法和装置。 导管包括适于与心脏腔室和靶容器流体连通的第一和第二部分。 导管位于血液源和目标血管之间的心肌外部，并在目标血管内腔内的多个方向输送血液。 可以由任何合适的合成血管移植材料形成的导管通常是T形的，腿部具有设置在靶容器中的两个自由端，优选通过无缝线的附件固定到其上。 导管包括血管移植材料，并且可以以各种方式制造，例如从任何合适的生物相容性材料模制导管或从一个或多个血管移植物材料制造导管。