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公开(公告)号:US20150132249A1
公开(公告)日:2015-05-14
申请号:US14590590
申请日:2015-01-06
Applicant: Abbott Cardiovascular Systems, Inc.
Inventor: Gina Zhang , Jessica Renee DesNoyer , Gordon Stewart , Maricela Kezis , Syed Faiyaz Ahmed Hossainy
IPC: A61K47/48 , C08G69/44 , A61K31/436
CPC classification number: A61K31/436 , A61K9/0019 , A61K47/595 , A61L24/001 , A61L24/046 , A61L2430/36 , C08G69/44 , Y10S977/906 , C08L77/12
Abstract: A composition including a solution suitable for introduction into a blood vessel comprising particles including a treatment agent and a tunable stimuli-responsive polymer. A method including introducing a delivery device into a blood vessel; and introducing a solution into the blood vessel, the solution including particles comprising a treatment agent and a tunable stimuli-responsive polymer. A method including combining a treatment agent and a tunable stimuli-responsive polymer; and forming particles of the combination suitable for delivery through a blood vessel.
Abstract translation: 一种包含适于引入血管的溶液的组合物,其包含包含处理剂和可调节刺激响应性聚合物的颗粒。 一种包括将输送装置引入血管的方法; 并且将溶液引入血管中,所述溶液包括包含处理剂和可调节刺激响应性聚合物的颗粒。 一种包括处理剂和可调谐刺激响应性聚合物的组合的方法; 以及形成适于通过血管输送的组合颗粒。
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公开(公告)号:US09067000B2
公开(公告)日:2015-06-30
申请号:US14083226
申请日:2013-11-18
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor: Jessica Renee DesNoyer , Stephen Dirk Pacetti , Vidya Nayak , Lothar Kleiner
CPC classification number: C08G69/48 , A61L27/34 , A61L31/041 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/416 , C08G69/44 , Y10T428/31551 , Y10T428/31725 , C08L77/12
Abstract: This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of vascular diseases.
Abstract translation: 本发明涉及包含灭活的末端氨基和羧基的聚(酯酰胺)(PEA),合成灭活的PEAs的方法及其用于治疗血管疾病的用途。
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公开(公告)号:US20140107148A1
公开(公告)日:2014-04-17
申请号:US14083226
申请日:2013-11-18
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor: Jessica Renee DesNoyer , Stephen Dirk Pacetti , Vidya Nayak , Lothar Kleiner
CPC classification number: C08G69/48 , A61L27/34 , A61L31/041 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/416 , C08G69/44 , Y10T428/31551 , Y10T428/31725 , C08L77/12
Abstract: This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of vascular diseases.
Abstract translation: 本发明涉及包含灭活的末端氨基和羧基的聚(酯酰胺)(PEA),合成灭活的PEAs的方法及其用于治疗血管疾病的用途。
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公开(公告)号:US20130129794A1
公开(公告)日:2013-05-23
申请号:US13731875
申请日:2012-12-31
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor: Lothar Walter Kleiner , Jessica Renee DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy , O. Mikael Trollsas , Michael Huy Ngo
IPC: A61L27/34
CPC classification number: A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
Abstract: Implantable medical devices including a coating having a bioactive agent and a poly(ester amide) polymer. Methods of forming these coatings are also described.
Abstract translation: 可植入医疗装置,包括具有生物活性剂和聚(酯酰胺)聚合物的涂层。 还描述了形成这些涂层的方法。
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公开(公告)号:US20150267000A1
公开(公告)日:2015-09-24
申请号:US14732568
申请日:2015-06-05
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor: Jessica Renee DesNoyer , Stephen Dirk Pacetti , Vidya Nayak , Lothar Kleiner
CPC classification number: C08G69/48 , A61L27/34 , A61L31/041 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/416 , C08G69/44 , Y10T428/31551 , Y10T428/31725 , C08L77/12
Abstract: This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of vascular diseases.
Abstract translation: 本发明涉及包含灭活的末端氨基和羧基的聚(酯酰胺)(PEA),合成灭活的PEAs的方法及其用于治疗血管疾病的用途。
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