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公开(公告)号：US20150297380A1
公开(公告)日：2015-10-22
申请号：US14687843
申请日：2015-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Benjamyn Serna , Michael Huy Ngo , Syed F.A. Hossainy , O. Mikael Trollsas
CPC classification number: A61F2/95 , A61F2210/0076 , A61F2230/0063 , A61F2240/001 , A61F2250/0067 , A61L2420/02 , B05D1/002 , B05D1/38 , B05D3/10 , B05D3/12
Abstract: Embodiments of the present invention encompass methods of forming coatings, particularly coatings for medical devices, and more particularly, for braided or woven medical devices. Embodiments of the present invention encompass the coatings and the coated devices. The coatings may include a polymer and optionally a therapeutic agent.
Abstract translation: 本发明的实施例包括形成涂层的方法，特别是用于医疗装置的涂层，更具体地，涉及编织或编织的医疗装置。 本发明的实施例包括涂层和涂覆装置。 涂层可以包括聚合物和任选的治疗剂。
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公开(公告)号：US20140212476A1
公开(公告)日：2014-07-31
申请号：US14227589
申请日：2014-03-27
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Dariush Davalian , John Stankus , Yuet Mei Khong , O. Mikael Trollsas , Syed F.A. Hossainy
IPC: A61K9/127 , A61K31/439 , A61K47/48 , A61K41/00
CPC classification number: A61K9/127 , A61K9/107 , A61K9/1273 , A61K31/439 , A61K47/6911
Abstract: This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions.
Abstract translation: 本发明涉及疏水性药物或疏水性药物与光动力治疗剂的组合的靶向递送，其通过使药物与血清脂蛋白的复合而形成，所述血清脂蛋白与这种血管病变具有亲和力并且积聚在血管损伤中。
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公开(公告)号：US09345668B2
公开(公告)日：2016-05-24
申请号：US14542983
申请日：2014-11-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael H. Ngo , David J. Sherman , Syed F. A. Hossainy
IPC: A61F2/00 , A61K31/56 , A61K31/33 , A61K31/497 , A61L31/16 , A61L27/34 , A61K9/50 , A61K38/13 , A61K38/44 , A61K45/06 , A61L31/10 , A61K47/34 , A61K31/436
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
Abstract translation: 本发明提供具有包含缓慢溶解性聚合物或材料的涂层的可植入装置及其制造和使用方法。
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4.发明申请Polymer Blends For Drug Delivery Stent Matrix With Improved Thermal Stability 审中-公开用于具有改进的热稳定性的药物递送支架基质的聚合物共混物公开(公告)号：US20140335143A1
公开(公告)日：2014-11-13
申请号：US14279234
申请日：2014-05-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Florencia Lim , Bozena Z. Maslanka , Yiwen Tang , O. Mikael Trollsas
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L2420/02 , A61L2420/06 , C08L67/04 , C09D167/04 , C08L2666/18
Abstract: Various embodiments of the present invention generally relate to a polymer blend composition used for coating a medical device that exhibits improved thermal stability. The invention also encompasses implantable medical devices coated the aforementioned coating.
Abstract translation: 本发明的各种实施方案一般涉及用于涂覆显示改善的热稳定性的医疗装置的聚合物共混物组合物。 本发明还包括涂覆上述涂层的可植入医疗装置。
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公开(公告)号：US08865189B2
公开(公告)日：2014-10-21
申请号：US13731875
申请日：2012-12-31
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy , O. Mikael Trollsas , Michael Huy Ngo
CPC classification number: A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
Abstract: Implantable medical devices including a coating having a bioactive agent and a poly(ester amide) polymer. Methods of forming these coatings are also described.
Abstract translation: 可植入医疗装置，包括具有生物活性剂和聚（酯酰胺）聚合物的涂层。 还描述了形成这些涂层的方法。
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Patent Agency Ranking
公开(公告)号：US20140127279A1
公开(公告)日：2014-05-08
申请号：US14152867
申请日：2014-01-10
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael Huy Ngo , David J. Sherman , Syed Faiyaz Ahmed Hossainy
IPC: A61K47/34
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
Abstract translation: 本发明提供具有包含缓慢溶解性聚合物或材料的涂层的可植入装置及其制造和使用方法。
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公开(公告)号：US20130230564A1
公开(公告)日：2013-09-05
申请号：US13770988
申请日：2013-02-19
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Lothar W. Kleiner , Yiwen Tang , Syed Faiyaz Ahmed Hossainy , Florencia Lim , Michael Huy Ngo , O. Mikael Trollsas
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L31/16 , A61L2300/416 , C08L67/04 , C08L77/12
Abstract: The present invention provides a coating comprising a semi-crystalline polymer on an implantable device and methods of making and using the same.
Abstract translation: 本发明提供一种包含可植入装置上的半结晶聚合物的涂层及其制备和使用方法。
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公开(公告)号：US09629944B2
公开(公告)日：2017-04-25
申请号：US15160999
申请日：2016-05-20
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： O. Mikael Trollsas , Michael H. Ngo , David J. Sherman , Syed F. A. Hossainy
IPC: A61F2/00 , A61L31/16 , A61L27/34 , A61L31/10 , A61K31/33 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/44 , A61K45/06 , A61K47/34 , A61K9/50 , A61K31/436 , A61L31/14
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
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公开(公告)号：US09468707B2
公开(公告)日：2016-10-18
申请号：US14752637
申请日：2015-06-26
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , O. Mikael Trollsas
IPC: A61F2/00 , A61F13/00 , A61K38/00 , A61F2/04 , A61L31/10 , A61L29/04 , A61L29/16 , A61L31/04 , A61L31/16 , A61K31/436 , A61L31/06 , C08G81/00
CPC classification number: A61L31/10 , A61K31/436 , A61L29/041 , A61L29/16 , A61L31/048 , A61L31/06 , A61L31/16 , A61L2300/606 , A61L2420/00 , C08G81/00
Abstract: The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.
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公开(公告)号：US20150374885A1
公开(公告)日：2015-12-31
申请号：US14752637
申请日：2015-06-26
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , O. Mikael Trollsas
CPC classification number: A61L31/10 , A61K31/436 , A61L29/041 , A61L29/16 , A61L31/048 , A61L31/06 , A61L31/16 , A61L2300/606 , A61L2420/00 , C08G81/00
Abstract: The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.
Abstract translation: 本发明涉及由可生物降解的，生物可吸收的三嵌段共聚物和含有这种聚合材料的可植入装置（例如药物递送支架）制成的聚合材料。 聚合物材料还可含有至少一种治疗物质。 配制聚合物材料以改善这些材料的机械和粘合性能，降解，生物相容性和药物渗透性，从而改善由这些材料形成的可植入装置。
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