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    MULTILAYER BALLOON FOR A CATHETER
    1.
    发明申请
    MULTILAYER BALLOON FOR A CATHETER 审中-公开
    用于导管的多层气泡

    公开(公告)号：US20150290434A1

    公开(公告)日：2015-10-15

    申请号：US14443805

    申请日：2013-11-18

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： Tung-Liang Lin ,  Jeong S. Lee ,  Roseminda J. White ,  Kenneth L. Wantink

    IPC: A61M25/10

    CPC classification number: A61M25/10 ,  A61F2/958 ,  A61L29/126 ,  A61L29/14 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/1075 ,  A61M2025/1084 ,  C08L77/00

    Abstract: Multilayer balloon for a catheter comprises a first layer made of a first polymer material having a first Shore durometer hardness, a second layer made of a second polymer material having a second Shore durometer hardness greater than the first Shore durometer hardness, wherein the second layer is an inner layer relative to the first layer, and a third layer made of a third polymer material having a third Shore durometer hardness less the first Shore durometer hardness, wherein the third layer is an inner layer relative to the second layer. Method of making a multilayer balloon for a catheter and a balloon catheter are also provided.

    Abstract translation: 用于导管的多层气囊包括由具有第一肖氏硬度计硬度的第一聚合物材料制成的第一层，由具有大于第一肖氏硬度计硬度的第二肖氏硬度计硬度的第二聚合物材料制成的第二层，其中第二层为 相对于第一层的内层，以及由第三聚合物材料制成的第三层，其具有比第一肖氏硬度计硬度小的第三肖氏硬度硬度，其中第三层是相对于第二层的内层。 还提供了制造用于导管和球囊导管的多层气囊的方法。

    Manufacturing processes for making medical devices having a coating gradient
    2.
    发明授权
    Manufacturing processes for making medical devices having a coating gradient 有权
    制造具有涂层梯度的医疗装置的制造方法

    公开(公告)号：US08747940B2

    公开(公告)日：2014-06-10

    申请号：US13749483

    申请日：2013-01-24

    Applicant: Abbott Cardiovascular Systems Inc.

    Inventor： Jeong S. Lee ,  Kenneth L. Wantink

    IPC: B05D3/02 ,  A61M25/00 ,  B05D1/32

    CPC classification number: B05D5/08 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/42 ,  A61L2400/10 ,  C08L39/06 ,  C08L71/02

    Abstract: Methods for forming a “coating gradient” on medical devices, such as a balloon catheter or guidewire are disclosed. The balloon portion of the catheter has a protective covering initially placed over it to prevent the balloon from receiving a first hydrophilic coating. After a first hydrophilic coating is applied, the protective covering is removed. A second hydrophilic coating could be applied to the catheter. A guidewire having less lubricity at the distal end portion also can be created. A first hydrophilic coating is applied to the elongated shaft and distal shaft section of the guidewire. After the first hydrophilic coating cures, the first hydrophilic coating is removed from a portion of the distal shaft section of the guidewire. A second hydrophillic coating can then be applied to the elongated shaft and distal shaft section of the guidewire. The second hydrophilic coating can be allowed to cure.

    Abstract translation: 公开了在诸如气囊导管或导丝的医疗装置上形成“涂层梯度”的方法。 导管的气囊部分具有最初放置在其上的防护罩，以防止气囊接收第一亲水性涂层。 在施加第一亲水涂层之后，去除保护层。 可以将第二亲水涂层施加到导管上。 也可以形成在前端部具有较少润滑性的导丝。 将第一亲水涂层施加到导丝的细长轴和远端轴部分。 在第一亲水涂层固化之后，第一亲水涂层从导丝的远端轴部分的一部分去除。 然后可以将第二亲水涂层施加到导丝的细长轴和远侧轴部分。 可以使第二亲水涂层固化。

    Catheter having monolithic multilayer distal outer member
    3.
    发明授权
    Catheter having monolithic multilayer distal outer member 有权

    公开(公告)号：US10426933B2

    公开(公告)日：2019-10-01

    申请号：US14843074

    申请日：2015-09-02

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： Jeong S. Lee ,  Kenneth L. Wantink

    IPC: A61M25/10 ,  A61M25/00 ,  A61M25/01

    Abstract: Balloon catheter includes an outer shaft including a hypotube and a monolithic multilayer distal outer member and having an inflation lumen defined therethrough, a balloon in fluid communication with the inflation lumen, and an inner tubular member having a guidewire lumen defined therethrough. The monolithic multilayer distal outer member has a proximal end portion and a distal end portion. The monolithic multilayer distal outer member has an inner layer comprising a first polymer having a tensile strength greater than about 8,000 psi and an outer layer comprising a second polymer having a flexural modulus of less than about 130,000 psi at room temperature. A proximal end of the monolithic multilayer distal outer member is coupled to the hypotube. The monolithic multilayer distal outer member is necked to a reduced diameter along at least a portion of a length thereof. The balloon has a proximal balloon shaft coupled to a distal end of the monolithic multilayer distal outer member. The inner tubular member extends distally from a proximal port in the proximal end portion of the monolithic multilayer distal outer member through at least a portion of the balloon.

    MANUFACTURING PROCESSES FOR MAKING MEDICAL DEVICES HAVING A COATING GRADIENT
    6.
    发明申请
    MANUFACTURING PROCESSES FOR MAKING MEDICAL DEVICES HAVING A COATING GRADIENT 有权
    用于制造具有涂层梯度的医疗装置的制造方法

    公开(公告)号：US20130136847A1

    公开(公告)日：2013-05-30

    申请号：US13749483

    申请日：2013-01-24

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： Jeong S. Lee ,  Kenneth L. Wantink

    IPC: B05D5/08

    CPC classification number: B05D5/08 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/42 ,  A61L2400/10 ,  C08L39/06 ,  C08L71/02

    Abstract: Methods for forming a “coating gradient” on medical devices, such as a balloon catheter or guidewire are disclosed. The balloon portion of the catheter could have a protective covering initially placed over it to prevent the balloon from receiving a first hydrophilic coating. After a first hydrophilic coating is applied to the catheter, the protective covering can be removed exposing the uncoated surface of the balloon. Next, after the protective covering has been removed, a second hydrophilic coating could be applied to the catheter. A guidewire having less lubricity at the distal end portion of the guidewire than the shaft portion which extends proximally away from the distal end section can be created. The method includes the application of a first hydrophilic coating on the elongated shaft and distal shaft section of the guidewire. This first hydrophilic coating is then allowed to cure. Next, the first hydrophilic coating is removed from a portion of the distal shaft section of the guidewire. After the first coating has been removed, a second hydrophillic coating can be applied to the elongated shaft and distal shaft section of the guidewire. The second hydrophilic coating can be allowed to cure.

    Abstract translation: 公开了在诸如气囊导管或导丝的医疗装置上形成“涂层梯度”的方法。 导管的气囊部分可以具有最初放置在其上的保护性覆盖物，以防止气囊接收第一亲水性涂层。 在对导管施加第一亲水涂层之后，可以去除保护性覆盖物，暴露气球的未涂覆表面。 接下来，在保护覆盖物被去除之后，可以将第二亲水涂层施加到导管。 可以产生在导丝的远端部处具有比远离远端部分向远侧延伸的轴部更小的润滑性的导丝。 该方法包括在导丝的细长轴和远端轴部分上施加第一亲水性涂层。 然后使该第一亲水涂层固化。 接下来，从引导线的远侧轴部的一部分去除第一亲水性涂层。 在去除第一涂层之后，可以将第二亲水涂层施加到导丝的细长轴和远侧轴部分。 可以使第二亲水涂层固化。

    CATHETER HAVING MONOLITHIC MULTILAYER DISTAL OUTER MEMBER
    8.
    发明申请
    CATHETER HAVING MONOLITHIC MULTILAYER DISTAL OUTER MEMBER 审中-公开
    具有单层多层超声波外部成员的导管

    公开(公告)号：US20160339211A1

    公开(公告)日：2016-11-24

    申请号：US14843074

    申请日：2015-09-02

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： Jeong S. Lee ,  Kenneth L. Wantink

    IPC: A61M25/10 ,  A61M25/00

    CPC classification number: A61M25/10 ,  A61M25/0045 ,  A61M25/1027 ,  A61M25/1029 ,  A61M2025/0046 ,  A61M2025/0059 ,  A61M2025/0183

    Abstract: Balloon catheter includes an outer shaft including a hypotube and a monolithic multilayer distal outer member and having an inflation lumen defined therethrough, a balloon in fluid communication with the inflation lumen, and an inner tubular member having a guidewire lumen defined therethrough. The monolithic multilayer distal outer member has a proximal end portion and a distal end portion. The monolithic multilayer distal outer member has an inner layer comprising a first polymer having a tensile strength greater than about 8,000 psi and an outer layer comprising a second polymer having a flexural modulus of less than about 130,000 psi at room temperature. A proximal end of the monolithic multilayer distal outer member is coupled to the hypotube. The monolithic multilayer distal outer member is necked to a reduced diameter along at least a portion of a length thereof. The balloon has a proximal balloon shaft coupled to a distal end of the monolithic multilayer distal outer member. The inner tubular member extends distally from a proximal port in the proximal end portion of the monolithic multilayer distal outer member through at least a portion of the balloon.

    Abstract translation: 气球导管包括外轴，包括海波管和单片多层远端外部构件，并且具有限定在其中的充气腔，与膨胀腔流体连通的气囊，以及具有通过其限定的导丝腔的内管状构件。 整体式多层远端外部构件具有近端部分和远端部分。 整体式多层远端外部构件具有包含第一聚合物的内层，其具有大于约8,000psi的拉伸强度，外层包含在室温下具有小于约130,000psi的挠曲模量的第二聚合物。 整体式多层远端外部构件的近端联接到海波管。 整体式多层远端外部构件沿其长度的至少一部分颈缩到减小的直径。 球囊具有联接到整体式多层远端外部构件的远端的近端球轴。 内部管状构件通过气囊的至少一部分从整体式多层远端外部构件的近端部分中的近端口向远侧延伸。

    Soft Tip Balloon Catheter
    9.
    发明申请
    Soft Tip Balloon Catheter 审中-公开
    软提示气球导管

    公开(公告)号：US20140358176A1

    公开(公告)日：2014-12-04

    申请号：US14463088

    申请日：2014-08-19

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： Kenneth L. Wantink ,  Jeong S. Lee ,  Justin K. Mann

    IPC: B29C65/02 ,  A61M25/10

    CPC classification number: B29C65/02 ,  A61M25/001 ,  A61M25/10 ,  A61M25/1034 ,  A61M2025/0047 ,  A61M2025/0081 ,  A61M2025/1075 ,  A61M2025/1093 ,  B29K2677/00 ,  B29K2995/0049 ,  B29L2009/00 ,  B29L2022/022 ,  B29L2023/005 ,  B29L2031/7543 ,  Y10T156/1005 ,  Y10T156/1015

    Abstract: Method for fabricating a balloon catheter including providing an inner tubular member having a distal section and a distal end with a lumen extending therein and forming a balloon having a distal leg with a first segment having a first diameter and a first wall thickness and a second segment having a second wall thickness. The second diameter is greater than the first diameter and the first wall thickness is greater than the second wall thickness. The distal end section of the inner tubular member can be positioned in the balloon and bonded to the first segment while reducing the diameter of the second segment. Method also provided for fabricating a multilayer balloon catheter including removing at least a portion of an outer layer from the distal leg of the balloon.

    Abstract translation: 一种用于制造球囊导管的方法，包括提供具有远侧部分和远端的内部管状构件，所述内部管状构件具有在其中延伸的内腔，并且形成具有远端腿部的气囊，所述远端腿部具有第一部分，所述第一部分具有第一直径和第一壁厚， 具有第二壁厚。 第二直径大于第一直径，第一壁厚大于第二壁厚。 内管状构件的远端部分可以定位在球囊中并且结合到第一段上，同时减小第二段的直径。 还提供了用于制造多层气囊导管的方法，其包括从气囊的远端腿部移除外层的至少一部分。

    Catheter Shaft and Method of Forming Same
    10.
    发明申请
    Catheter Shaft and Method of Forming Same 审中-公开
    导管轴及其形成方法

    公开(公告)号：US20140276401A1

    公开(公告)日：2014-09-18

    申请号：US14212966

    申请日：2014-03-14

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

    Inventor： Jeong S. Lee ,  Kenneth L. Wantink

    IPC: A61M25/00 ,  A61M25/10

    CPC classification number: A61M25/0045 ,  A61L29/041 ,  A61L29/06 ,  A61L29/085 ,  A61L29/14 ,  A61M25/0009 ,  A61M25/1036 ,  A61M25/104 ,  A61M2025/0183 ,  C08L77/00 ,  C08L77/12 ,  C08L71/12 ,  C08L67/02 ,  C08L23/12

    Abstract: Elongate, flexible catheter includes an elongated shaft having a proximal end, a distal end, and a lumen defined therein. The shaft includes a tubular member having an outer layer and an inner layer. The outer layer includes a first polymer selected from the group consisting of nylon 12, polyether block amide, and combinations thereof. The inner layer includes a second polymer having a heat deflection temperature greater than about 53° C. selected from the group consisting of nylon 11, nylon 6, nylon 6,6, nylon 6,12, polyamide-imide, polyetherimide, polypropylene, polyethylene terephthalate, polybutylene terephthalate, polyethereetherketone, and combinations thereof. Method of making an elongate, flexible catheter is also provided.

    Abstract translation: 细长的柔性导管包括细长轴，其具有近端，远端和限定在其中的内腔。 轴包括具有外层和内层的管状构件。 外层包括选自尼龙12，聚醚嵌段酰胺及其组合的第一聚合物。 内层包括热变形温度大于约53℃的第二聚合物，其选自尼龙11，尼龙6，尼龙6,6，尼龙6,12，聚酰胺酰亚胺，聚醚酰亚胺，聚丙烯，聚乙烯 对苯二甲酸酯，聚对苯二甲酸丁二醇酯，聚醚醚酮及其组合。 还提供了制造细长柔性导管的方法。

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