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公开(公告)号:US20170174624A1
公开(公告)日:2017-06-22
申请号:US15398978
申请日:2017-01-05
Applicant: AbbVie Inc.
Inventor: Dominique Bonafoux , Heather M. Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep K. Somal , Jennifer Van Camp , Stacy A. Van Epps , Anil Vasudevan , Grier A. Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D209/08 , C07D405/14 , C07D403/04 , C07D401/04 , C07D209/18 , C07D405/04 , C07D209/12 , C07D209/10 , C07D209/14 , C07D417/14 , C07D401/14 , C07D409/14 , C07D403/10 , C07D409/04 , C07D409/12 , C07D403/14 , C07D413/04
CPC classification number: C07D209/08 , A61P35/00 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US20150005279A1
公开(公告)日:2015-01-01
申请号:US14315504
申请日:2014-06-26
Applicant: ABBVIE INC.
Inventor: Dominique Bonafoux , Heather M. Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep K. Somal , Jennifer Van Camp , Stacy A. Van Epps , Anil Vasudevan , Grier A. Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D487/04 , C07D471/04 , C07D209/08 , C07D401/12 , C07D401/14 , C07D403/14 , C07D231/56 , C07D417/12 , C07D417/14
CPC classification number: C07D209/08 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
Abstract translation: 本发明提供式(I)化合物,其药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号:US20210179556A1
公开(公告)日:2021-06-17
申请号:US17173613
申请日:2021-02-11
Applicant: AbbVie Inc.
Inventor: Dominique Bonafoux , Heather Michele Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep Kaur Somal , Jennifer Van Camp , Stacy Anne Van Epps , Anil Vasudevan , Grier Allan Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D209/08 , C07D487/04 , C07D417/12 , C07D471/04 , C07D417/14 , C07D401/14 , C07D403/14 , C07D231/56 , C07D401/12 , A61P35/00 , C07D513/04 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US10280184B2
公开(公告)日:2019-05-07
申请号:US15304131
申请日:2015-04-16
Applicant: AbbVie Inc.
Inventor: Michael M. Friedman , Philip Cox , Kristine E. Frank , Michael Z. Hoemann , Augustine Osuma , Noel S. Wilson , Xiangdong Xu , Kevin Cusack , Raymond Huntley , J. Martin Herold
IPC: C07D471/04 , C07D519/00 , A61K31/437 , C07D487/04 , C07D498/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US09567339B2
公开(公告)日:2017-02-14
申请号:US14315504
申请日:2014-06-26
Applicant: AbbVie Inc.
Inventor: Dominique Bonafoux , Heather M. Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep K. Somal , Jennifer Van Camp , Stacy A. Van Epps , Anil Vasudevan , Grier A. Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D487/04 , C07D417/12 , C07D471/04 , C07D209/08 , C07D417/14 , C07D401/14 , C07D403/14 , C07D231/56 , C07D401/12
CPC classification number: C07D209/08 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
Abstract translation: 本发明提供式(I)化合物,其药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号:US20190135836A1
公开(公告)日:2019-05-09
申请号:US16230408
申请日:2018-12-21
Applicant: AbbVie Inc.
Inventor: Michael Friedman , Phil Cox , Kristine E. Frank , Michael Z. Hoemann , Augustine Osuma , Noel S. Wilson , Xiangdong Xu , Kevin Cusack , Raymond Huntley , J. Martin Herold
IPC: C07D519/00 , A61K31/437 , C07D471/04 , C07D487/04 , C07D498/04
Abstract: This invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers, and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US20190284135A1
公开(公告)日:2019-09-19
申请号:US16421006
申请日:2019-05-23
Applicant: AbbVie Inc.
Inventor: Dominique Bonafoux , Heather Michele Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep Kaur Somal , Jennifer Van Camp , Stacy Anne Van Epps , Anil Vasudevan , Grier Allan Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D209/08 , C07D487/04 , C07D405/14 , C07D231/56 , C07D403/14 , C07D401/14 , C07D417/14 , C07D471/04 , C07D417/12 , A61P35/00 , C07D513/04 , C07D209/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D209/10 , C07D209/12 , C07D413/04 , C07D209/18 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/04 , C07D401/12
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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