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公开(公告)号：US20190284135A1
公开(公告)日：2019-09-19
申请号：US16421006
申请日：2019-05-23
Applicant: AbbVie Inc.
Inventor： Dominique Bonafoux , Heather Michele Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep Kaur Somal , Jennifer Van Camp , Stacy Anne Van Epps , Anil Vasudevan , Grier Allan Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D209/08 , C07D487/04 , C07D405/14 , C07D231/56 , C07D403/14 , C07D401/14 , C07D417/14 , C07D471/04 , C07D417/12 , A61P35/00 , C07D513/04 , C07D209/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D209/10 , C07D209/12 , C07D413/04 , C07D209/18 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/04 , C07D401/12
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号：US20180086737A1
公开(公告)日：2018-03-29
申请号：US15670708
申请日：2017-08-07
Applicant: AbbVie Inc.
Inventor： Maria Argiriadi , Eric Breinlinger , Justin D. Dietrich , Michael Friedman , David Ihle , Michael Morytko , Kelly Mullen , Augustine Osuma , Gloria Y. LoSchiavo , Noel S. Wilson
IPC: C07D403/04 , C07F9/6558 , C07D401/14 , C07D413/04 , C07D471/04 , C07D498/04 , C07D491/107 , C07D487/04 , C07D417/14 , C07D417/04 , C07D403/14 , C07D401/04 , C07D413/14 , C07D405/14 , C07D405/04
CPC classification number: C07D403/04 , C07D401/04 , C07D401/14 , C07D403/14 , C07D405/04 , C07D405/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/107 , C07D498/04 , C07F9/65583
Abstract: The disclosure provides indazolone compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the disclosure may be useful for treating immunological and oncological conditions.
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公开(公告)号：US20170174624A1
公开(公告)日：2017-06-22
申请号：US15398978
申请日：2017-01-05
Applicant: AbbVie Inc.
Inventor： Dominique Bonafoux , Heather M. Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep K. Somal , Jennifer Van Camp , Stacy A. Van Epps , Anil Vasudevan , Grier A. Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D209/08 , C07D405/14 , C07D403/04 , C07D401/04 , C07D209/18 , C07D405/04 , C07D209/12 , C07D209/10 , C07D209/14 , C07D417/14 , C07D401/14 , C07D409/14 , C07D403/10 , C07D409/04 , C07D409/12 , C07D403/14 , C07D413/04
CPC classification number: C07D209/08 , A61P35/00 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号：US20150005279A1
公开(公告)日：2015-01-01
申请号：US14315504
申请日：2014-06-26
Applicant: ABBVIE INC.
Inventor： Dominique Bonafoux , Heather M. Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep K. Somal , Jennifer Van Camp , Stacy A. Van Epps , Anil Vasudevan , Grier A. Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D487/04 , C07D471/04 , C07D209/08 , C07D401/12 , C07D401/14 , C07D403/14 , C07D231/56 , C07D417/12 , C07D417/14
CPC classification number: C07D209/08 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
Abstract translation: 本发明提供式（I）化合物，其药学上可接受的盐，前药，生物活性代谢物，立体异构体和异构体，其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号：US20190135836A1
公开(公告)日：2019-05-09
申请号：US16230408
申请日：2018-12-21
Applicant: AbbVie Inc.
Inventor： Michael Friedman , Phil Cox , Kristine E. Frank , Michael Z. Hoemann , Augustine Osuma , Noel S. Wilson , Xiangdong Xu , Kevin Cusack , Raymond Huntley , J. Martin Herold
IPC: C07D519/00 , A61K31/437 , C07D471/04 , C07D487/04 , C07D498/04
Abstract: This invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers, and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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Patent Agency Ranking
公开(公告)号：US09856253B2
公开(公告)日：2018-01-02
申请号：US15130362
申请日：2016-04-15
Applicant: AbbVie Inc.
Inventor： Eric C. Breinlinger , Phil B. Cox , Justin Dietrich , Kristine E. Frank , Michael M. Friedman , Huan-Qui Li , Kenton Longenecker , Augustine Osuma , Ann Marie Rowley , Anil Vasudevan , Noel Wilson
IPC: C07D227/00 , C07D471/04 , C07D471/14 , C07D487/04 , C07D498/04 , C07D498/14 , C07D498/18 , C07D498/20 , C07D498/22 , C07D519/00 , C07D471/18 , C07D491/147 , C07D491/22
CPC classification number: C07D471/04 , C07D471/14 , C07D471/18 , C07D487/04 , C07D491/147 , C07D491/22 , C07D498/04 , C07D498/14 , C07D498/18 , C07D498/20 , C07D498/22 , C07D519/00
Abstract: The invention provides tricyclic heterocyclic compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the invention may be useful for treating immunological and oncological conditions.
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公开(公告)号：US20210179556A1
公开(公告)日：2021-06-17
申请号：US17173613
申请日：2021-02-11
Applicant: AbbVie Inc.
Inventor： Dominique Bonafoux , Heather Michele Davis , Kristine E. Frank , Michael M. Friedman , J. Martin Herold , Michael Z. Hoemann , Raymond Huntley , Augustine Osuma , George Sheppard , Gagandeep Kaur Somal , Jennifer Van Camp , Stacy Anne Van Epps , Anil Vasudevan , Grier Allan Wallace , Lu Wang , Lu Wang , Zhi Wang , Noel S. Wilson , Xiangdong Xu
IPC: C07D209/08 , C07D487/04 , C07D417/12 , C07D471/04 , C07D417/14 , C07D401/14 , C07D403/14 , C07D231/56 , C07D401/12 , A61P35/00 , C07D513/04 , C07D209/10 , C07D209/12 , C07D209/14 , C07D209/18 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04
Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号：US10273238B2
公开(公告)日：2019-04-30
申请号：US15852179
申请日：2017-12-22
Applicant: AbbVie Inc.
Inventor： Eric C. Breinlinger , Andrew Burchat , Justin Dietrich , Michael Friedman , David Ihle , David Kinsman , Kelly Mullen , Augustine Osuma , Anil Vasudevan , Noel S. Wilson
IPC: C07D487/04 , C07D519/00 , C07D498/04
Abstract: The disclosure provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the disclosure are useful for treating immunological and oncological conditions.
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公开(公告)号：US20160304526A1
公开(公告)日：2016-10-20
申请号：US15130323
申请日：2016-04-15
Applicant: AbbVie Inc.
Inventor： Eric Breinlinger , Andrew Burchat , Justin Dietrich , Michael Friedman , David Ihle , David Kinsman , Kelly Mullen , Augustine Osuma , Anil Vasudevan , Noel Wilson
IPC: C07D487/04 , C07D498/04 , C07D519/00
CPC classification number: C07D487/04 , C07D498/04 , C07D519/00
Abstract: The disclosure provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the disclosure are useful for treating immunological and oncological conditions.
Abstract translation: 药学上可接受的盐，前药，生物活性代谢物，立体异构体和异构体，其中变量在本文中定义。 本公开的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号：US20160304517A1
公开(公告)日：2016-10-20
申请号：US15130362
申请日：2016-04-15
Applicant: AbbVie Inc.
Inventor： Eric C. Breinlinger , Phil B. Cox , Jerome Daanen , Justin Dietrich , Stevan Djuric , Amanda W. Dombrowski , Kristine E. Frank , Michael M. Friedman , Arthur Gomtsyan , Huan-Qui Li , Kenton Longenecker , Augustine Osuma , Ann Marie Rowley , Robert Schmidt , Anil Vasudevan , Noel Wilson
IPC: C07D471/04 , C07D491/147 , C07D491/22 , C07D498/04 , C07D471/18 , C07D471/14 , C07D498/22 , C07D498/14 , C07D498/20 , C07D487/04 , C07D519/00
CPC classification number: C07D471/04 , C07D471/14 , C07D471/18 , C07D487/04 , C07D491/147 , C07D491/22 , C07D498/04 , C07D498/14 , C07D498/18 , C07D498/20 , C07D498/22 , C07D519/00
Abstract: The invention provides tricyclic heterocyclic compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the invention may be useful for treating immunological and oncological conditions.
Abstract translation: 本发明提供三环杂环化合物，药学上可接受的盐，前药，生物活性代谢物，立体异构体和异构体，其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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