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公开(公告)号：US08883186B2
公开(公告)日：2014-11-11
申请号：US13734858
申请日：2013-01-04
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Stephen Dirk Pacetti
IPC: A61F2/00 , A61F13/00 , C09D129/04 , A61L27/16 , A61L27/54 , A61L31/10 , A61L31/16 , C09D129/06
CPC classification number: A61L31/10 , A61L27/16 , A61L27/30 , A61L27/54 , A61L31/16 , C09D129/04 , C09D129/06 , C08L29/02
Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
Abstract translation: 一种基于聚烯烃衍生物的医疗器械聚合物涂层。 描述了各种聚合物以制备用于医疗装置的涂层，特别是用于药物递送支架。 聚合物包括具有至少一种烯烃衍生单元和至少一种衍生自乙烯醇，烯丙醇及其衍生物的单元的均聚物，共聚物和三元共聚物。
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公开(公告)号：US08734817B2
公开(公告)日：2014-05-27
申请号：US13631399
申请日：2012-09-28
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Dirk Pacetti
IPC: A61K9/00 , C08F251/00
CPC classification number: A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
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公开(公告)号：US09173982B2
公开(公告)日：2015-11-03
申请号：US13734860
申请日：2013-01-04
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Stephen Dirk Pacetti
IPC: A61F13/00 , A61F2/00 , A61L31/10 , A61L27/16 , A61L27/54 , A61L31/16 , C09D129/04 , C09D129/06 , A61L27/30
CPC classification number: A61L31/10 , A61L27/16 , A61L27/30 , A61L27/54 , A61L31/16 , C09D129/04 , C09D129/06 , C08L29/02
Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
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4.发明授权Coatings for implantable devices comprising poly(hydroxy-alkanoates) and diacid linkages 有权用于可植入装置的涂料包括聚（羟基链烷酸酯）和二酸键公开(公告)号：US08758801B2
公开(公告)日：2014-06-24
申请号：US13686392
申请日：2012-11-27
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Stephen Dirk Pacetti , Thierry Glauser
CPC classification number: A61L31/10 , A61L27/34 , C08G63/66 , C09D167/00
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包括包含至少一种聚（羟基酸）或聚（羟基 - 链烷酸酯）嵌段的嵌段聚合物，至少一个生物相容性聚合物的嵌段和至少 一种类型的连接部分。
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公开(公告)号：US08906394B2
公开(公告)日：2014-12-09
申请号：US13631387
申请日：2012-09-28
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Dirk Pacetti
IPC: A61K9/00 , A61F2/00 , C08F251/00 , A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785
CPC classification number: A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
Abstract translation: 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。
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Patent Agency Ranking
6.发明授权Coatings for implantable devices comprising poly(hydroxy-alkanoates) and diacid linkages 有权用于可植入装置的涂料包括聚（羟基链烷酸酯）和二酸键公开(公告)号：US08586075B2
公开(公告)日：2013-11-19
申请号：US13686380
申请日：2012-11-27
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Stephen Dirk Pacetti , Thierry Glauser
CPC classification number: A61L31/10 , A61L27/34 , C08G63/66 , C09D167/00
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings include block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
Abstract translation: 公开了用于植入式医疗装置的涂层及其制造方法，所述涂层包括包含至少一种聚（羟基酸）或聚（羟基 - 链烷酸酯）嵌段的至少一种生物相容性聚合物的至少一个嵌段 一种类型的连接部分。
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7.发明申请COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES 有权用于包含聚（羟基 - 烷基）酸酯和双向连接的可植入装置的涂料公开(公告)号：US20130123422A1
公开(公告)日：2013-05-16
申请号：US13686380
申请日：2012-11-27
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Stephen Dirk Pacetti , Thierry Glauser
IPC: A61L27/34
CPC classification number: A61L31/10 , A61L27/34 , C08G63/66 , C09D167/00
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings include block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
Abstract translation: 公开了用于植入式医疗装置的涂层及其制造方法，所述涂层包括包含至少一种聚（羟基酸）或聚（羟基 - 链烷酸酯）嵌段的至少一种生物相容性聚合物的至少一个嵌段 一种类型的连接部分。
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8.发明申请COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES 有权用于包含聚（羟基 - 烷基）酸酯和双向连接的可植入装置的涂料公开(公告)号：US20130116380A1
公开(公告)日：2013-05-09
申请号：US13686392
申请日：2012-11-27
Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
Inventor： Stephen Dirk Pacetti , Thierry Glauser
IPC: C09D167/00
CPC classification number: A61L31/10 , A61L27/34 , C08G63/66 , C09D167/00
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包括包含至少一种聚（羟基酸）或聚（羟基 - 链烷酸酯）嵌段的嵌段聚合物，至少一个生物相容性聚合物的嵌段和至少 一种类型的连接部分。
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公开(公告)号：US08846836B2
公开(公告)日：2014-09-30
申请号：US13631026
申请日：2012-09-28
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Thierry Glauser , Syed Faiyaz Ahmed Hossainy , Connie Kwok , Stephen Dirk Pacetti , Eugene Michal
IPC: A61F2/00 , C07H3/00 , C08B37/00 , C12P19/04 , A61K31/727 , A61K31/785 , A61K31/728 , A61L31/10
CPC classification number: A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
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公开(公告)号：US20130150460A1
公开(公告)日：2013-06-13
申请号：US13734858
申请日：2013-01-04
Applicant: Advanced Cardiovascular Systems, Inc.
Inventor： Stephen Dirk Pacetti
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L27/16 , A61L27/30 , A61L27/54 , A61L31/16 , C09D129/04 , C09D129/06 , C08L29/02
Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
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