-
公开(公告)号:US20230280254A1
公开(公告)日:2023-09-07
申请号:US18160948
申请日:2023-01-27
Applicant: Aerosol Dynamics Inc. , Washington University
Inventor: Jian Wang , Steven Russel Spielman , Jiaoshi Zhang , Susanne Vera Hering , Jing Li
CPC classification number: G01N15/0266 , G01N1/2202 , G01N2001/2223
Abstract: A system and method to measure a size distribution of particles based on their electrical mobility. The method includes: introducing, via a sheath flow inlet, a particle free sheath flow into a chamber formed by two parallel walls which are separated by a gap, the chamber having a width and a length, the sheath flow having a direction along the length of the chamber and flowing a laminar manner; introducing an aerosol sample flow into the chamber downstream of the sheath inlet such that the aerosol sample flow joins the particle free sheath flow in a laminar manner; applying an electric field between the two parallel walls of the chamber, the field having a strength which varies across the width of the chamber; extracting an output aerosol flow through a first outlet downstream of the sample inlet; and outputting an excess flow equal to a sum of the sheath flow and aerosol sample flow minus the output aerosol flow. The method may also include: passing the output aerosol flow through a growth cell in a laminar manner, the growth cell having a region of wetted walls with two or more temperature regions such that the particles within the output aerosol flow grow by condensation to form droplets, and such that relative positions of droplets are indicative of particle electrical mobility; and counting and capturing a spatial position of individual droplets exiting the growth cell.
-
公开(公告)号:US20220026333A1
公开(公告)日:2022-01-27
申请号:US17494449
申请日:2021-10-05
Applicant: Aerosol Dynamics Inc.
Inventor: Susanne Vera Hering , Gregory Stephen Lewis , Steven Russel Spielman
IPC: G01N15/06
Abstract: A method and apparatus to create water vapor supersaturation and particulate counts from an air sample. The method and apparatus include introducing an air sample into a chamber by passing a flow into the chamber through the inlet by pumping at the outlet. The method further includes closing the inlet while continuing the pumping to exhaust the air sample from the chamber through the outlet. The pumping is performed at a rate operable to reduce pressure inside the chamber such that the air sample in the central portion of the chamber cools, and water vapor from walls of the chamber has time to diffuse into the air sample in the chamber from the walls. The cycles are repeated by continuously repeating the introducing and closing. The walls of the chamber may be wet or dry.
-
3.
公开(公告)号:US20150024379A1
公开(公告)日:2015-01-22
申请号:US14378768
申请日:2013-02-19
Applicant: RESEARCH TRIANGLE INSTITUTE , AEROSOL DYNAMICS INC.
Inventor: David S. Ensor , Howard Jerome Walls , Karin K. Foarde , Susanne Vera Hering , Steven Russel Spielman
IPC: C12Q1/24
CPC classification number: C12Q1/24
Abstract: An aerosol collection system and method. The system includes a bio-aerosol delivery device configured to supply bioparticles in a gas stream, a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream, and an aerosol collection medium downstream from the moisture exchange device and configured to collect the bioparticles. The method includes delivering bioparticles in a gas stream, humidifying or dehumidifying the bioparticles in the gas stream by transport of water across a partition member and into a vapor phase of the gas stream, and collecting the bioparticles by a collection medium.
Abstract translation: 气溶胶收集系统及方法。 该系统包括构造成供应气流中的生物颗粒的生物气溶胶输送装置,水分交换装置,其包括耦合到气流的分隔构件,并被配置为对气流中的生物颗粒进行加湿或除湿;以及下游的气溶胶收集介质 从湿度交换装置并配置成收集生物颗粒。 该方法包括在气流中输送生物颗粒,通过将水输送通过分隔构件并进入气流的气相来加湿或除湿气流中的生物颗粒,以及通过收集介质收集生物颗粒。
-
公开(公告)号:US12234440B2
公开(公告)日:2025-02-25
申请号:US16912486
申请日:2020-06-25
Inventor: Arantzazu Eiguren Fernandez , Gregory Stephen Lewis , Steven Russel Spielman , Chang-Yu Wu , Trevor Benson Tilly
Abstract: An apparatus and method for the delivery and deposition of particles air-liquid-interface (ALI) cell cultures includes a sample inlet coupled to a growth tube having interior walls that are wet. The growth tube is configured to operate at a first temperature along a first length of the tube and a second temperature along a second length positioned between the first length and a growth tube outlet. The apparatus also includes a nozzle plate having a plurality of nozzles. The exposure chamber adapted to hold cell cultures at an air-liquid interface positioned underneath the plurality of nozzles and a temperature regulator adapted to control a temperature of the exposure chamber. The apparatus also includes a controller including instructions operable to cause the controller to maintain a relative humidity within the exposure chamber by controlling at least the second temperature of the growth tube and the temperature of the exposure chamber.
-
公开(公告)号:US11029240B2
公开(公告)日:2021-06-08
申请号:US16159604
申请日:2018-10-12
Applicant: Aerosol Dynamics Inc.
Inventor: Susanne Vera Hering , Steven Russel Spielman , Gregory Stephen Lewis
Abstract: A wick liquid sensor suitable for use in a particle condensation device is provided. The sensor includes a light source configured to illuminate a surface of the wick. A detector is configured to detect wick reflected light from the light source and determine the intensity of reflected light. The wick is formed from a porous media that is wettable by the liquid, and becomes translucent when filled with the liquid. The amount of reflectivity decreases as the saturation content of the liquid in the wick increases.
-
公开(公告)号:US10378042B2
公开(公告)日:2019-08-13
申请号:US14378768
申请日:2013-02-19
Applicant: RESEARCH TRIANGLE INSTITUTE , AEROSOL DYNAMICS INC.
Inventor: David S. Ensor , Howard Jerome Walls , Karin K. Foarde , Susanne Vera Hering , Steven Russel Spielman
IPC: C12Q1/24
Abstract: An aerosol collection system and method. The system includes a bio-aerosol delivery device configured to supply bioparticles in a gas stream, a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream, and an aerosol collection medium downstream from the moisture exchange device and configured to collect the bioparticles. The method includes delivering bioparticles in a gas stream, humidifying or dehumidifying the bioparticles in the gas stream by transport of water across a partition member and into a vapor phase of the gas stream, and collecting the bioparticles by a collection medium.
-
公开(公告)号:US20140033915A1
公开(公告)日:2014-02-06
申请号:US14043455
申请日:2013-10-01
Applicant: Aerosol Dynamics Inc.
Inventor: Susanne Vera Hering , Steven Russel Spielman , Gregory Stephen Lewis , Nathan Michael Kreisberg
IPC: B01D47/00
CPC classification number: B01D47/00 , B01D5/0009 , B01D53/1475 , B01D53/18 , F25J3/08 , F25J2200/70 , G01M15/102 , G01N15/06 , G01N15/065 , G01N2015/0038 , G01N2015/1481
Abstract: A system and method for particle enlargement with continuously wetted wicks includes a container into which a flow of particle-laden air is introduced in a laminar manner through an inlet and to an outlet. The container has a first section, a second section and a third section though which the particle-laden air flows between the inlet and the outlet. The temperature of the second section is warmer than that of the first section at the inlet and the third section at the outlet. In one embodiment, a continuous wick spanning an interior wall of the first second, second section and third section, said wick being capable of internally transporting liquid water along its length is provided. Alternatively, a wick characterized by a bubble point pressure has one side in contact with air and an opposing side mounted adjacent to the interior wall of a housing with a gap formed between the wick and the housing, wherein the wick is used with a water reservoir such that the pressure difference between the air flow and the water filled gap is less than the bubble point pressure of the wick material.
Abstract translation: 具有连续润湿的芯的颗粒增大的系统和方法包括容器,通过入口和出口以层流方式将颗粒载气的空气流引入该容器中。 容器具有第一部分,第二部分和第三部分,通过该第一部分,颗粒载满的空气在入口和出口之间流动。 第二部分的温度比入口处的第一部分和出口处的第三部分的温度更暖。 在一个实施例中,提供横跨第一第二,第二部分和第三部分的内壁的连续的芯,所述芯能够沿其长度内部输送液态水。 或者,以泡点压力为特征的芯具有与空气接触的一侧,并且相邻侧安装在壳体的内壁附近,在芯和壳体之间形成有间隙,其中芯与水槽一起使用 使得空气流与填充水的间隙之间的压差小于芯材料的泡点压力。
-
公开(公告)号:US12111241B2
公开(公告)日:2024-10-08
申请号:US17568940
申请日:2022-01-05
Applicant: Aerosol Dynamics Inc.
Inventor: Susanne Vera Hering , Gregory Stephen Lewis , Steven Russel Spielman
IPC: G01N15/06 , G01N15/075
CPC classification number: G01N15/06 , G01N15/075
Abstract: A method and apparatus to create water vapor supersaturation and particulate counts from an air sample. The method and apparatus include introducing an air sample into a chamber connected to an optical detector and an outlet by pumping at the outlet. The method further includes passing air through the chamber and optical detector in a steady flow, and subsequently closing the inlet while continuing the pumping to expand the air sample and exhaust a portion of the air sample through the optical detector. The walls of the particle chamber are wetted with a fluid such as water, and one portion of the wall is warmer than the other portions such that there is some condensational growth prior to the expansion, and yet more condensational growth during the expansion. The cycles are repeated by continuously repeating the introducing, passing and closing.
-
公开(公告)号:US11789166B2
公开(公告)日:2023-10-17
申请号:US16911368
申请日:2020-06-24
Applicant: Aerosol Dynamics Inc.
Inventor: Susanne Vera Hering , Gregory Stephen Lewis , Steven Russel Spielman , Mark R. Stolzenberg
CPC classification number: G01T1/171 , G01N15/0205 , G01N15/0211 , G01N15/065 , G01N15/1459 , G01T1/172
Abstract: An approach for counting particles suspended in a flow of gas or liquid in instruments that direct the flow through an illuminated region. Pulses are detected when the signal is below a threshold amplitude and moves above the threshold amplitude. This movement above the threshold creates a dead time during which only one pulse is detected until the signal amplitude moves sufficiently below the threshold such that a subsequent particle creates a distinct pulse. After counting the number of pulses, and determining the measured live time that the signal is below the threshold value, an initial particle concentration is calculated, and the calculation corrected for coincidence by calculating an actual live time as a measured live time minus a constant multiplied by the number of distinctly counted pulses, where the constant has the units of time. From this, particle concentrations in a volume can be determined.
-
公开(公告)号:US11237091B2
公开(公告)日:2022-02-01
申请号:US16671594
申请日:2019-11-01
Applicant: Aerosol Dynamics Inc.
Inventor: Susanne Vera Hering , Arantzazu Eiguren Fernandez , Gregory Stephen Lewis , Steven Russel Spielman , Philip Bourgeois
Abstract: A particle growth apparatus includes a temperature-controlled humidifier coupled to a water-based condensation growth system. The humidifier may include a tube of sulfonated tetrafluoroethylene-based fluoropolymer-copolymer and surrounded by a region containing water or water vapor. The apparatus includes a wetted wick and wick sensor in the condensation growth system, configured such that the gas sample flows through the sulfonated tetrafluoroethylene-based fluoropolymer-copolymer tube into the condensation growth system.
-
-
-
-
-
-
-
-
-