公开(公告)号：US20190008814A1

公开(公告)日：2019-01-10

申请号：US16129875

申请日：2018-09-13

Applicant: AJINOMOTO CO., INC.

Inventor： Tomoyuki MINE ,  Ryo Uchida ,  Naoki Hayashi

IPC: A61K31/202 ,  A61K35/60 ,  A61K31/198

Abstract: Compositions which contain an amino acid containing serine and a lipid containing a n-3 fatty acid are useful for the prophylaxis or improvement of peripheral neuropathy.

公开(公告)号：US20160374381A1

公开(公告)日：2016-12-29

申请号：US15247070

申请日：2016-08-25

Applicant: AJINOMOTO CO., INC.

Inventor： Tomoyuki Mine ,  Naoki Hayashi ,  Itaru Kon ,  Kazunori Saima

IPC: A23L33/12

CPC classification number: A23L33/12 ,  A23L2/52 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/17 ,  A23L33/175 ,  A23L33/18 ,  A23V2002/00 ,  A61K31/07 ,  A61K31/198 ,  A61K31/20 ,  A61K31/202 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4415 ,  A61K31/51 ,  A61K31/525 ,  A61K31/714 ,  A61K33/04 ,  A61K33/30 ,  A61K38/05 ,  A61K2300/00

Abstract: A nutritional composition is provided which has an effective prophylactic and/or improving effect for various symptoms of muscle mass decrease, decreased basal metabolism, low body temperature, suppression of obesity, suppression of visceral fat accumulation, hyperglycemia, hyperlipidemia and the like in elderly people. The nutritional composition can include n-3 fatty acid and one or more of free lysine, dipeptides containing lysine, and lysine salts, wherein the content of free lysine, dipeptides containing lysine, and/or lysine salts is 0.1 g-10.0 g per 100 kcal of the composition, and the content of the total amount of n-3 fatty acid is 0.17 g-5.00 g per 100 kcal of the composition.

Abstract translation: 提供了一种营养组合物，其对于老年人的肌肉量减少，基础代谢降低，体温低，抑制肥胖，抑制内脏脂肪积聚，高血糖，高脂血症等的各种症状具有有效的预防和/或改善效果 。 营养组合物可包括n-3脂肪酸和游离赖氨酸，含有赖氨酸的二肽和赖氨酸盐中的一种或多种，​​其中游离赖氨酸，含有赖氨酸和/或赖氨酸的二肽的含量为0.1g-10.0g / 100 kcal的组成，并且n-3脂肪酸的总量的含量为每100千卡组合物0.17g-5.00g。

公开(公告)号：US20140044828A1

公开(公告)日：2014-02-13

申请号：US14051576

申请日：2013-10-11

Applicant: AJINOMOTO CO., INC.

Inventor： Tomoyuki Mine ,  Naoki Hayashi ,  Itaru Kon ,  Kazunori Saima

IPC: A23L1/30 ,  A23L1/305 ,  A23L1/304 ,  A23L1/302 ,  A23L1/303

CPC classification number: A23L33/12 ,  A23L2/52 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/17 ,  A23L33/175 ,  A23L33/18 ,  A23V2002/00 ,  A61K31/07 ,  A61K31/198 ,  A61K31/20 ,  A61K31/202 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4415 ,  A61K31/51 ,  A61K31/525 ,  A61K31/714 ,  A61K33/04 ,  A61K33/30 ,  A61K38/05 ,  A61K2300/00

Abstract: A nutritional composition is provided which has an effective prophylactic and/or improving effect for various symptoms of muscle mass decrease, decreased basal metabolism, low body temperature, suppression of obesity, suppression of visceral fat accumulation, hyperglycemia, hyperlipidemia and the like in elderly people. The nutritional composition can include n-3 fatty acid and one or more of free lysine, dipeptides containing lysine, and lysine salts, wherein the content of free lysine, dipeptides containing lysine, and/or lysine salts is 0.1 g-10.0 g per 100 kcal of the composition, and the content of the total amount of n-3 fatty acid is 0.17 g-5.00 g per 100 kcal of the composition.

Abstract translation: 提供了一种营养组合物，其对于老年人的肌肉量减少，基础代谢降低，体温低，抑制肥胖，抑制内脏脂肪积聚，高血糖，高脂血症等各种症状具有有效的预防和/或改善效果 。 营养组合物可以包括n-3脂肪酸和游离赖氨酸，含有赖氨酸的二肽和赖氨酸盐中的一种或多种，​​其中游离赖氨酸，含有赖氨酸和/或赖氨酸的二肽的含量为0.1g-10.0g / 100 kcal的组成，并且n-3脂肪酸的总量的含量为每100千卡组合物0.17g-5.00g。

公开(公告)号：US10136669B2

公开(公告)日：2018-11-27

申请号：US15247070

申请日：2016-08-25

Applicant: AJINOMOTO CO., INC.

Inventor： Tomoyuki Mine ,  Naoki Hayashi ,  Itaru Kon ,  Kazunori Saima

IPC: A23L33/12 ,  A61K31/07 ,  A61K31/198 ,  A61K31/20 ,  A61K31/202 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4415 ,  A61K31/51 ,  A61K31/525 ,  A61K31/714 ,  A61K33/04 ,  A61K33/30 ,  A61K38/05 ,  A23L2/52 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/17 ,  A23L33/175 ,  A23L33/18

Abstract: A nutritional composition is provided which has an effective prophylactic and/or improving effect for various symptoms of muscle mass decrease, decreased basal metabolism, low body temperature, suppression of obesity, suppression of visceral fat accumulation, hyperglycemia, hyperlipidemia and the like in elderly people. The nutritional composition can include n-3 fatty acid and one or more of free lysine, dipeptides containing lysine, and lysine salts, wherein the content of free lysine, dipeptides containing lysine, and/or lysine salts is 0.1 g-10.0 g per 100 kcal of the composition, and the content of the total amount of n-3 fatty acid is 0.17 g-5.00 g per 100 kcal of the composition.

公开(公告)号：US20130243933A1

公开(公告)日：2013-09-19

申请号：US13869120

申请日：2013-04-24

Applicant: AJINOMOTO CO., INC.

Inventor： Itaru Kon ,  Naoki Hayashi ,  Tatsuro Tanaka ,  Hisayuki Uneyama ,  Shinji Somekawa

IPC: A23L1/29

CPC classification number: A23L1/296 ,  A23L33/40 ,  A61K35/20

Abstract: The present invention relates to a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that the volume-based median size (d50) of particles in the nutrient composition is 5 to 100 μm and water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition, or a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition and the mass of the protein with respect to the total moles of divalent ions forming the water-insoluble particles is 1.5 to 3 g/mmol.

Abstract translation: 本发明涉及至少含有碳水化合物，脂质，蛋白质和矿物质，并且是液体或半固体的营养组合物，其特征在于，营养组合物中颗粒的基于体积的中值大小（d50）为 作为营养组合物的主要成分，含有至少含有碳水化合物，脂质，蛋白质和矿物质的营养成分，含有5〜100μm的具有不溶于二价阳离子的蛋白质的水不溶性粒子，以及 是液体或半固体，其特征在于含有不溶于二价阳离子的蛋白质的水不溶性颗粒作为营养组合物的主要组分，并且蛋白质的质量相对于形成水不溶性的二价离子的总摩尔数 颗粒为1.5〜3g / mmol。

公开(公告)号：US10653655B2

公开(公告)日：2020-05-19

申请号：US16129875

申请日：2018-09-13

Applicant: AJINOMOTO CO., INC.

Inventor： Tomoyuki Mine ,  Ryo Uchida ,  Naoki Hayashi

IPC: A61K31/202 ,  A61K31/198 ,  A61K35/60

Abstract: Compositions which contain an amino acid containing serine and a lipid containing a n-3 fatty acid are useful for the prophylaxis or improvement of peripheral neuropathy.

公开(公告)号：US08747939B2

公开(公告)日：2014-06-10

申请号：US13869120

申请日：2013-04-24

Applicant: Ajinomoto Co., Inc.

Inventor： Itaru Kon ,  Naoki Hayashi ,  Tatsuro Tanaka ,  Hisayuki Uneyama ,  Shinji Somekawa

IPC: A23J1/00

CPC classification number: A23L1/296 ,  A23L33/40 ,  A61K35/20

Abstract: The present invention relates to a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that the volume-based median size (d50) of particles in the nutrient composition is 5 to 100 μm and water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition, or a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition and the mass of the protein with respect to the total moles of divalent ions forming the water-insoluble particles is 1.5 to 3 g/mmol.

Abstract translation: 本发明涉及至少含有碳水化合物，脂质，蛋白质和矿物质，并且是液体或半固体的营养组合物，其特征在于，营养组合物中颗粒的基于体积的中值大小（d50）为 作为营养组合物的主要成分，含有至少含有碳水化合物，脂质，蛋白质和矿物质的营养成分，含有具有由二价阳离子不溶解的蛋白质的水不溶性粒子，以及 是液体或半固体，其特征在于含有不溶于二价阳离子的蛋白质的水不溶性颗粒作为营养组合物的主要成分，并且蛋白质的质量相对于形成水不溶性的二价离子的总摩尔数 颗粒为1.5〜3g / mmol。