公开(公告)号：US20130288313A1

公开(公告)日：2013-10-31

申请号：US13938601

申请日：2013-07-10

Applicant: Ajinomoto Co., Inc.

Inventor： Yuri Nagai ,  Kazuyuki Hayashi ,  Takuji Ueda ,  Yoshihiro Usuda ,  Kazuhiko Matsui

IPC: C12P13/08

CPC classification number: C12P13/08 ,  C12P13/04

Abstract: An L-amino acid is produced by culturing a microorganism belonging to the family Enterobacteriaceae having an L-amino acid-producing ability and modified so that glycerol dehydrogenase and dihydroxyacetone kinase activities are increased, in a medium containing glycerol as a carbon source to produce and accumulate an L-amino acid in the medium or cells, and collecting the L-amino acid from the medium or the cells.

Abstract translation: 通过在含有甘油作为碳源的培养基中培养属于具有L-氨基酸生产能力的肠杆菌科的微生物并进行修饰以使甘油脱氢酶和二羟基丙酮激酶活性增加的L-氨基酸产生， 在培养基或细胞中积累L-氨基酸，并从培养基或细胞中收集L-氨基酸。

公开(公告)号：US20140287472A1

公开(公告)日：2014-09-25

申请号：US14301438

申请日：2014-06-11

Applicant: AJINOMOTO CO., INC.

Inventor： Konstantin Vyacheslavovich Rybak ,  Ekaterina Aleksandrovna Slivinskaya ,  Ekaterina Alekseevna Savrasova ,  Valeriy Zavenovich Akhverdian ,  Elena Vitalievna Klyachko ,  Sergei Vladimirovich Mashko ,  Vera Georgievna Doroshenko ,  Larisa Gotlibovna Airikh ,  Tatyana Viktorovna Leonova ,  Mikhail Markovich Gusyatiner ,  Elvira Borisovna Voroshilova ,  Yury Ivanovich Kozlov ,  Yoshihiko Hara ,  Takuji Ueda

IPC: C12P13/04 ,  C12P13/24 ,  C12P13/10 ,  C12P13/08

CPC classification number: C12P13/04 ,  C12P13/08 ,  C12P13/10 ,  C12P13/24

Abstract: There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease.

Abstract translation: 公开了使用肠杆菌科的细菌生产L-氨基酸的方法，例如L-苏氨酸，L-赖氨酸，L-组氨酸，L-苯丙氨酸，L-精氨酸或L-谷氨酸，其中细菌 已被修饰以增强D-木糖通透酶的活性。