公开(公告)号：US20220362104A1

公开(公告)日：2022-11-17

申请号：US17770355

申请日：2020-10-23

申请人： AMGEN INC. ,  AMGEN RESEARCH MUNICH GMBH

发明人： Cornelius Pompe ,  Nicholas J. Clark ,  Wei Qi ,  Arnold J. McAuley ,  MIchael Schneider ,  Chia-Jung Wu ,  Twinkle R. Christian ,  Heather N. Franey ,  Bharadwaj Jagannathan ,  Jeffrey Abel ,  Franz Dietzel

IPC分类号： A61J1/14 ,  A61M5/14 ,  G01N33/15

摘要： An approach for determining material compatibility for components of a drug delivery system is provided that includes using surface zeta-potential analytical method to evaluate surface interactions between a desired molecule and at least one material present within a given IV-bag system.

公开(公告)号：US20220087901A1

公开(公告)日：2022-03-24

申请号：US17425412

申请日：2020-02-12

申请人： AMGEN INC.

发明人： Nicholas J. Clark ,  Chia-Jung Wu ,  Mingda Eu ,  Artemio A. Alanis ,  Jennifer Lyn Sawicky ,  Monica Goss ,  Jennifer Stevenson ,  Heather N. Franey ,  Deirdre Piedmonte ,  Stephen Robert Brych

IPC分类号： A61J1/20 ,  A61M39/00

摘要： An approach for preparing a drug delivery device includes providing a prefilled delivery container and transferring a drug product contained in a drug container to the prefilled delivery container. The prefilled delivery container includes a container body containing a predetermined quantity of saline solution and a predetermined quantity of IV stabilizing solution (“IVSS”). The drug product is transferred to the prefilled delivery container via a delivery container adapter.

公开(公告)号：US20200253823A1

公开(公告)日：2020-08-13

申请号：US16782306

申请日：2020-02-05

申请人： AMGEN INC.

发明人： Chia-Jung Wu ,  Nicholas J. Clark ,  Ronak Maheshwari ,  Heather N. Franey

IPC分类号： A61J1/10 ,  A61J1/14 ,  A61J1/16

摘要： A drug delivery system includes a delivery container, a first drug insertion port, at least one additional drug insertion port, and an IV connection port. The delivery container includes upper, lower, first side, and second side portions, and further includes a tapered region extending between the first side portion and the second side portion. The first drug insertion port is positioned at the lower portion of the delivery container and has a first coupling mechanism. The at least one additional drug insertion port is also positioned at the lower portion of the delivery container, but includes a second coupling mechanism that is different than the first coupling mechanism. The IV connection port is positioned at the lower portion of the delivery container adjacent to a lower portion of the tapered region.