公开(公告)号：US09388447B2

公开(公告)日：2016-07-12

申请号：US14821574

申请日：2015-08-07

Applicant: Amgen Inc.

Inventor： Matthew I. Jerums ,  Amanda Kano ,  Henry Lin ,  Shun Luo ,  Jian Wu ,  Rebecca E. McCoy ,  Arvia E. Morris

IPC: C12N5/077 ,  C12P21/00 ,  C12N5/00

CPC classification number: C12P21/00 ,  C12N5/0037 ,  C12N5/0043 ,  C12N2500/32 ,  C12N2510/02 ,  C12N2511/00

Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.

公开(公告)号：US11427848B2

公开(公告)日：2022-08-30

申请号：US17537766

申请日：2021-11-30

Applicant: Amgen Inc.

Inventor： Chetan Goudar ,  Sean Cole ,  Nicole Sabo ,  Henry Lin ,  Jonathan Lull ,  Tharmala Tharmalingam

IPC: C12P21/00 ,  C12M3/00 ,  C12M1/00 ,  C12N5/00 ,  C12M1/36 ,  C07K16/00 ,  C12M1/26

Abstract: The invention provides methods and materials for culturing mammalian cells and harvesting recombinant protein.

公开(公告)号：US12195779B2

公开(公告)日：2025-01-14

申请号：US17746008

申请日：2022-05-17

Applicant: Amgen Inc.

Inventor： Chetan Goudar ,  Sean Cole ,  Nicole Sabo ,  Henry Lin ,  Jonathan Lull ,  Tharmala Tharmalingam

IPC: C12P21/00 ,  C07K16/00 ,  C12M1/00 ,  C12M1/26 ,  C12M1/36 ,  C12N5/00

Abstract: The invention provides methods and materials for culturing mammalian cells and harvesting recombinant protein.

公开(公告)号：US11384378B2

公开(公告)日：2022-07-12

申请号：US15316147

申请日：2015-06-04

Applicant: AMGEN INC.

Inventor： Chetan Goudar ,  Sean Cole ,  Nicole Le ,  Henry Lin ,  Jonathan Lull ,  Tharmala Tharmalingam

IPC: C12P21/00 ,  C12M3/00 ,  C12M1/00 ,  C12N5/00 ,  C12M1/36 ,  C07K16/00 ,  C12M1/26

Abstract: The invention provides methods and materials for culturing mammalian cells and harvesting recombinant protein.