-
公开(公告)号：US12084686B2
公开(公告)日：2024-09-10
申请号：US17051528
申请日：2019-04-30
Applicant: Amgen Inc.
Inventor： Christopher Kenyon Crowell , Jian Wu , Neil Kitchen , Alison Jean Gillespie , Simina Crina Petrovan , Michael Charles Brandenstein
CPC classification number: C12N5/0682 , C07K16/2875 , C07K2317/14 , C07K2317/92 , C12N2500/34
Abstract: This invention relates to recombinantly-expressed denosumab molecules and methods for modulating glycan profiles of denosumab molecules.
-
公开(公告)号：US11319568B2
公开(公告)日：2022-05-03
申请号：US16654933
申请日：2019-10-16
Applicant: AMGEN INC.
Inventor： Jian Wu , Sean Davern , Simina Crina Petrovan , Michael Charles Brandenstein , Katherine Rose Lindahl , Shawn Erik Lillie
Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.
-
公开(公告)号：US09822388B2
公开(公告)日：2017-11-21
申请号：US14776404
申请日：2014-03-10
Applicant: AMGEN INC.
Inventor： Jian Wu , Sean Davern , Simina Crina Petrovan , Michael Charles Brandenstein , Katherine Rose Lindahl , Shawn Erik Lillie
CPC classification number: C12P21/005 , C07K16/00 , C07K2317/14 , C07K2317/41 , C12N1/38 , C12N5/0037 , C12N2500/32 , C12N2500/34 , C12N2510/02
Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.
-
Patent Agency Ranking
公开(公告)号：US11459595B2
公开(公告)日：2022-10-04
申请号：US17554836
申请日：2021-12-17
Applicant: AMGEN INC.
Inventor： Jian Wu , Sean Davern , Simina Crina Petrovan , Michael Charles Brandenstein , Katherine Rose Lindahl , Shawn Erik Lillie
Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.
-
公开(公告)号：US11952605B2
公开(公告)日：2024-04-09
申请号：US18172670
申请日：2023-02-22
Applicant: AMGEN INC.
Inventor： Jian Wu , Sean Davern , Simina Crina Petrovan , Michael Charles Brandenstein , Katherine Rose Lindahl , Shawn Erik Lillie
CPC classification number: C12P21/005 , C07K16/00 , C12N1/38 , C12N5/0037 , C07K2317/14 , C07K2317/41 , C12N2500/32 , C12N2500/34 , C12N2510/02
Abstract: The present invention relates to methods of modulating the mannose content of recombinant proteins.
-
公开(公告)号：US10829551B2
公开(公告)日：2020-11-10
申请号：US15150627
申请日：2016-05-10
Applicant: AMGEN INC.
Inventor： Jian Wu , Nicole Sabo , Michael De La Cruz , Gregory Flynn
Abstract: The present invention relates to methods of modulating (e.g., reducing) the mannose content, particularly high-mannose content of recombinant glycoproteins.
-
公开(公告)号：US09388447B2
公开(公告)日：2016-07-12
申请号：US14821574
申请日：2015-08-07
Applicant: Amgen Inc.
Inventor： Matthew I. Jerums , Amanda Kano , Henry Lin , Shun Luo , Jian Wu , Rebecca E. McCoy , Arvia E. Morris
CPC classification number: C12P21/00 , C12N5/0037 , C12N5/0043 , C12N2500/32 , C12N2510/02 , C12N2511/00
Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.
-
公开(公告)号：US09359435B2
公开(公告)日：2016-06-07
申请号：US13741280
申请日：2013-01-14
Applicant: AMGEN INC.
Inventor： Jian Wu , Nicole Le , Michael De La Cruz , Gregory Flynn
IPC: A61K39/00 , A61K39/395 , C07K16/00 , C07K16/24 , C12P21/00
CPC classification number: C07K16/244 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/41 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C12N5/0037 , C12N2500/02 , C12N2500/12 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12P21/005
Abstract: The present invention relates to methods of modulating (e.g., reducing) the mannose content, particularly high-mannose content of recombinant glycoproteins.
-
-
-
-
-
-
-
Search Results
8
records
(took 0.013 seconds)
