公开(公告)号：US20200276154A1

公开(公告)日：2020-09-03

申请号：US16650140

申请日：2018-09-20

Applicant: AMOREPACIFIC CORPORATION

Inventor： Pil Joon PARK ,  Tae Ryong LEE ,  Eungyung CHO

IPC: A61K31/351 ,  A61K8/67 ,  A61K8/49 ,  A61Q19/00 ,  A23L29/00 ,  A23L33/155 ,  A61K47/10

Abstract: The present disclosure relates to a composition for promoting adipocyte differentiation or adiponectin production, including a trimethoxy phenyl compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an effective ingredient. A composition according to the present specification promotes adipocyte differentiation or adiponectin production, thereby exhibiting the effect of making the skin plump or increasing skin elasticity. Hence, the composition of the present specification can find various applications as a pharmaceutical composition or cosmetic composition in the field such as that concerning skin damage.

公开(公告)号：US20190004034A1

公开(公告)日：2019-01-03

申请号：US16023045

申请日：2018-06-29

Applicant: AMOREPACIFIC CORPORATION

Inventor： Sunghoon LEE ,  Il-Hong BAE ,  Daejin MIN ,  Soojung OH ,  Tae Ryong LEE ,  Eungyung CHO

IPC: G01N33/50 ,  C12N5/071

Abstract: According to an embodiment, a method of producing artificial skin includes mixing fibroblasts and collagen to form a dermis simulating layer, applying keratinocytes on the dermis simulating layer and culturing the same, culturing the dermis simulating layer in a first medium that is a keratinocyte medium, and culturing the dermis simulating layer that is cultured in the first medium in a second medium including a DMEM medium and a F12 medium.