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公开(公告)号：US20210041436A1
公开(公告)日：2021-02-11
申请号：US16896117
申请日：2020-06-08
Inventor： Stephen Johnston , Lu Wang
IPC: G01N33/569
Abstract: Assays, arrays, and methods for distinguishing a bacterial infection from a viral infection are disclosed. The antibiotic crisis is in part driven by over prescription of antibiotics. There is a tendency, particular in pediatrics, to give an antibiotic even for viral infections. Thus, embodiments herein are directed to the problem of distinguishing a bacterial infection from a viral infection to reduce unnecessary antibiotic usage.
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公开(公告)号：US20180284114A1
公开(公告)日：2018-10-04
申请号：US15764143
申请日：2016-09-30
Inventor： Stephen Johnston
IPC: G01N33/543
Abstract: Provided herein are methods for processing biopolymeric arrays, where conditions suitable for forming complexes of immobilized biopolymers (e.g., peptides) and target molecules of a sample can be varied independently of conditions suitable for detecting such complexes using a secondary detection reagent.
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公开(公告)号：US09970932B2
公开(公告)日：2018-05-15
申请号：US14773751
申请日：2014-03-14
Inventor： Neal Woodbury , Stephen Johnston , Zhan Gong Zhao , Matthew Greving
IPC: G01N33/543 , G01N27/62 , G01N33/53 , G01N33/68 , C12Q1/68
CPC classification number: G01N33/54366
Abstract: The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.
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公开(公告)号：US10712342B2
公开(公告)日：2020-07-14
申请号：US16480887
申请日：2018-01-31
Inventor： Stephen Johnston , Lu Wang
IPC: C12Q1/00 , G01N33/569
Abstract: Assays, arrays, and methods for distinguishing a bacterial infection from a viral infection are disclosed. The antibiotic crisis is in part driven by over prescription of antibiotics. There is a tendency, particular in pediatrics, to give an antibiotic even for viral infections. Thus, embodiments herein are directed to the problem of distinguishing a bacterial infection from a viral infection to reduce unnecessary antibiotic usage.
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公开(公告)号：US10011649B2
公开(公告)日：2018-07-03
申请号：US14913089
申请日：2014-08-25
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , Christopher Diehnelt , Nidhi Gupta , Valeriy Domenyuk , Zhan-Gong Zhao , Stephen Johnston
Inventor： Christopher Diehnelt , Nidhi Gupta , Valeriy Domenyuk , Zhan-Gong Zhao , Stephen Johnston
IPC: C07K16/28 , A61K38/00 , A61K39/395 , A61K39/00 , G01N33/53 , C07K16/10 , C07K14/11 , C07K14/00 , G01N33/569
CPC classification number: C07K16/1018 , A61K38/00 , C07K14/001 , C07K14/11 , C07K2318/20 , G01N33/56983 , G01N2333/11 , G01N2469/10
Abstract: Composition of synbodies that bind influenza. The synbodies are composed of two peptides joined on a scaffold.
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Patent Agency Ranking
公开(公告)号：US11360086B2
公开(公告)日：2022-06-14
申请号：US16896117
申请日：2020-06-08
Inventor： Stephen Johnston , Lu Wang
IPC: G01N33/53 , G01N33/569
Abstract: Assays, arrays, and methods for distinguishing a bacterial infection from a viral infection are disclosed. The antibiotic crisis is in part driven by over prescription of antibiotics. There is a tendency, particular in pediatrics, to give an antibiotic even for viral infections. Thus, embodiments herein are directed to the problem of distinguishing a bacterial infection from a viral infection to reduce unnecessary antibiotic usage.
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公开(公告)号：US20220170935A1
公开(公告)日：2022-06-02
申请号：US17651235
申请日：2022-02-15
Inventor： Stephen Johnston
IPC: G01N33/574 , C07K16/28 , G16B40/00 , G16H50/00 , G16H20/00 , G16H50/30 , G16H10/40 , G16H50/20 , G16H50/70 , G01N33/543
Abstract: Provided herein are methods for classifying how a subject having a cancer will respond to immunotherapeutic (IT) therapy based on the subject's immunosignature or frameshift signature. Also provided herein are methods for classifying a subject having a cancer as having a good prognosis or a poor prognosis based on the subject's immunosignature or frameshift signature.
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公开(公告)号：US20200209241A1
公开(公告)日：2020-07-02
申请号：US16647434
申请日：2018-09-13
Inventor： Stephen Johnston
IPC: G01N33/574 , C07K16/28
Abstract: Provided herein are methods for classifying how a subject having a cancer will respond to immunotherapeutic (IT) therapy based on the subject's immunosignature or frameshift signature. Also provided herein are methods for classifying a subject having a cancer as having a good prognosis or a poor prognosis based on the subject's immunosignature or frameshift signature.
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公开(公告)号：US20190361021A1
公开(公告)日：2019-11-28
申请号：US16480887
申请日：2018-01-31
Inventor： Stephen Johnston , Lu Wang
IPC: G01N33/569
Abstract: Assays, arrays, and methods for distinguishing a bacterial infection from a viral infection are disclosed. The antibiotic crisis is in part driven by over prescription of antibiotics. There is a tendency, particular in pediatrics, to give an antibiotic even for viral infections. Thus, embodiments herein are directed to the problem of distinguishing a bacterial infection from a viral infection to reduce unnecessary antibiotic usage.
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公开(公告)号：US20190234962A1
公开(公告)日：2019-08-01
申请号：US16116592
申请日：2018-08-29
Inventor： Stephen Johnston , Kurt Whittemore , Phillip Stafford , Lu Wang
CPC classification number: G01N33/6854 , G01N33/6848 , G16H50/20 , G16H50/50 , G16H50/80
Abstract: In certain embodiments, the present invention provides methods and compositions to measure unbiasedly the immune health status of an individual or population. A number of measures, including Shannon's entropy, can provide a measure of the diversity and disorder in the population of antibodies in a subject. The measure can be established by reacting the population of antibodies in a subject's blood with a complex surface, such as a peptide array.
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