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公开(公告)号：US10160730B2
公开(公告)日：2018-12-25
申请号：US15208329
申请日：2016-07-12
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Agostino Marasco , Giuseppe Alvaro , Anne Dècor , Dieter Hamprecht , Paolo Dambruoso , Simona Tommasi
IPC: C07D405/14 , C07D249/12 , C07D307/94 , C07D311/04 , C07D311/76 , C07D311/96 , C07D401/04 , C07D307/87 , C07C43/313 , C07C255/46 , C07C43/29 , C07C255/37 , C07C43/225 , C07C255/48
Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
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公开(公告)号：US11180461B2
公开(公告)日：2021-11-23
申请号：US16785083
申请日：2020-02-07
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Agostino Marasco , Giuseppe Alvaro , Anne Dècor , Dieter Hamprecht , Paolo Dambruoso , Simona Tommasi
IPC: C07D405/14 , C07D249/12 , C07D307/94 , C07D311/04 , C07D311/76 , C07D311/96 , C07D401/04 , C07D307/87 , C07C43/313 , C07C255/46 , C07C43/29 , C07C255/37 , C07C43/225 , C07C255/48 , C07D405/04
Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
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公开(公告)号：US20150111910A1
公开(公告)日：2015-04-23
申请号：US14403048
申请日：2013-05-22
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Agostino Marasco , Giuseppe Alvaro , Anne Dècor , Dieter Hamprecht , Paolo Dambruoso , Simona Tommasi
IPC: C07D249/12 , C07C255/37 , C07D311/96 , C07C43/29 , C07D311/76 , C07D307/94 , C07D405/14 , C07D307/87
CPC classification number: C07D249/12 , C07C43/225 , C07C43/29 , C07C43/313 , C07C255/37 , C07C255/46 , C07C255/48 , C07C2601/02 , C07D307/87 , C07D307/94 , C07D311/04 , C07D311/76 , C07D311/96 , C07D401/04 , C07D405/14
Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
Abstract translation: 式（I）化合物可用于调节Kv3.1，Kv.3.2和Kv3.3通道，并可用于治疗或预防相关疾病。
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公开(公告)号：US11197859B2
公开(公告)日：2021-12-14
申请号：US16985160
申请日：2020-08-04
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Giuseppe Alvaro , Paolo Dambruoso , Simona Tommasi , Anne Decor , Charles Large , Agostino Marasco
IPC: C07D413/12 , A61K31/506 , C07D405/12 , C07D413/14 , C07D307/79 , C07D307/94 , C07D405/14 , C07D317/46 , A61K31/4439
Abstract: The disclosure provides compounds of formula (I): said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
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公开(公告)号：US20190071405A1
公开(公告)日：2019-03-07
申请号：US16181864
申请日：2018-11-06
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Agostino Marasco , Giuseppe Alvaro , Anne Dècor , Dieter Hamprecht , Paolo Dambruoso , Simona Tommasi
IPC: C07D249/12 , C07C255/37 , C07C43/225 , C07C255/46 , C07C43/313 , C07D307/87 , C07D401/04 , C07D311/96 , C07D311/76 , C07D311/04 , C07D307/94 , C07D405/14 , C07C255/48 , C07C43/29
Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
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Patent Agency Ranking
公开(公告)号：US20200172496A1
公开(公告)日：2020-06-04
申请号：US16785083
申请日：2020-02-07
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Agostino Marasco , Giuseppe Alvaro , Anne Dècor , Dieter Hamprecht , Paolo Dambruoso , Simona Tommasi
IPC: C07D249/12 , C07D405/14 , C07D307/94 , C07D311/04 , C07D311/76 , C07D311/96 , C07D401/04 , C07D307/87 , C07C43/313 , C07C255/46 , C07C43/29 , C07C255/37 , C07C43/225 , C07C255/48
Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
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公开(公告)号：US10265316B2
公开(公告)日：2019-04-23
申请号：US15621400
申请日：2017-06-13
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Giuseppe Alvaro , Paolo Dambruoso , Simona Tommasi , Anne Decor , Charles Large , Agostino Marasco
IPC: C07D405/12 , A61K31/506 , C07D413/12 , C07D413/14 , C07D307/79 , C07D307/94 , C07D405/14 , C07D317/46 , A61K31/4439
Abstract: The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
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公开(公告)号：US11583527B2
公开(公告)日：2023-02-21
申请号：US17517620
申请日：2021-11-02
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Giuseppe Alvaro , Paolo Dambruoso , Simona Tommasi , Anne Decor , Charles Large , Agostino Marasco
IPC: C07D413/12 , A61K31/506 , C07D405/12 , C07D413/14 , C07D307/79 , C07D307/94 , C07D405/14 , C07D317/46 , A61K31/4439
Abstract: The disclosure provides compounds of formula (I): said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
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公开(公告)号：US20220054490A1
公开(公告)日：2022-02-24
申请号：US17517620
申请日：2021-11-02
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Giuseppe Alvaro , Paolo Dambruoso , Simona Tommasi , Anne Decor , Charles Large , Agostino Marasco
IPC: A61K31/506 , C07D413/12 , C07D405/12 , C07D413/14 , C07D307/79 , C07D307/94 , C07D405/14 , C07D317/46 , A61K31/4439
Abstract: The disclosure provides compounds of formula (I): said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
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公开(公告)号：US09422252B2
公开(公告)日：2016-08-23
申请号：US14403048
申请日：2013-05-22
Applicant: AUTIFONY THERAPEUTICS LIMITED
Inventor： Agostino Marasco , Giuseppe Alvaro , Anne Dècor , Dieter Hamprecht , Paolo Dambruoso , Simona Tommasi
IPC: C07D401/04 , C07D249/12 , C07D405/14 , C07D307/94 , C07D311/04 , C07D311/76 , C07D311/96 , C07D307/87 , C07C43/313 , C07C255/46 , C07C43/29 , C07C255/37
CPC classification number: C07D249/12 , C07C43/225 , C07C43/29 , C07C43/313 , C07C255/37 , C07C255/46 , C07C255/48 , C07C2601/02 , C07D307/87 , C07D307/94 , C07D311/04 , C07D311/76 , C07D311/96 , C07D401/04 , C07D405/14
Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
Abstract translation: 式（I）化合物可用于调节Kv3.1，Kv.3.2和Kv3.3通道，并可用于治疗或预防相关疾病。
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