公开(公告)号：US20160184281A1

公开(公告)日：2016-06-30

申请号：US14878836

申请日：2015-10-08

Applicant: AbbVie Inc.

Inventor： Richard F. Clark ,  Bryan Sorensen ,  Augustine T. Osuma ,  Robin Frey ,  Kenton Longenecker ,  George Doherty ,  Michael L. Curtin ,  Michael Michaelides ,  Ramzi Sweis ,  Marina Pliushchev ,  Andrew Judd ,  Todd Hansen ,  Howard R. Heyman

IPC: A61K31/437 ,  A61K31/4545 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/55 ,  A61K31/5377 ,  A61K31/444

CPC classification number: A61K31/437 ,  A61K31/407 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/5377 ,  A61K31/55 ,  A61K45/06 ,  C07D471/04 ,  C07D487/04 ,  A61K2300/00

Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

公开(公告)号：US20170135994A9

公开(公告)日：2017-05-18

申请号：US14878858

申请日：2015-10-08

Applicant: AbbVie Inc.

Inventor： Richard F. Clark ,  Bryan Sorensen ,  Augustine T. Osuma ,  Robin Frey ,  Kenton Longenecker ,  George Doherty ,  Michael L. Curtin ,  Michael Michaelides ,  Ramzi Sweis ,  Marina Pliushchev ,  Andrew Judd ,  Todd Hansen ,  Howard R. Heyman

IPC: A61K31/437 ,  A61K31/4545 ,  A61K31/496

CPC classification number: A61K31/437 ,  A61K31/407 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/5377 ,  A61K31/55 ,  A61K45/06 ,  C07D471/04 ,  C07D487/04 ,  A61K2300/00

Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

公开(公告)号：US20160184282A1

公开(公告)日：2016-06-30

申请号：US14878858

申请日：2015-10-08

Applicant: AbbVie Inc.

Inventor： Richard F. Clark ,  Bryan Sorensen ,  Augustine T. Osuma ,  Robin Frey ,  Kenton Longenecker ,  George Doherty ,  Michael L. Curtin ,  Michael Michaelides ,  Ramzi Sweis ,  Marina Pliushchev ,  Andrew Judd ,  Todd Hansen ,  Howard R. Heyman

IPC: A61K31/437 ,  A61K31/4545 ,  A61K31/496

CPC classification number: A61K31/437 ,  A61K31/407 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/5377 ,  A61K31/55 ,  A61K45/06 ,  C07D471/04 ,  C07D487/04 ,  A61K2300/00

Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.