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公开(公告)号：US20130303511A1
公开(公告)日：2013-11-14
申请号：US13891366
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , A61K45/06 , C07D487/04 , A61K31/4985 , A61K31/437 , A61K31/5377
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号：US20130303508A1
公开(公告)日：2013-11-14
申请号：US13891349
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , A61K31/5377 , A61K45/06 , A61K31/496 , A61K31/55 , A61K31/4725 , A61K31/437 , A61K31/4545
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号：US20180215764A1
公开(公告)日：2018-08-02
申请号：US15852179
申请日：2017-12-22
Applicant: AbbVie Inc.
Inventor： Eric C. Breinlinger , Andrew Burchat , Justin D. Dietrich , Michael Friedman , David Ihle , David Kinsman , Kelly Mullen , Augustine T. Osuma , Anil Vasudevan , Noel S. Wilson
IPC: C07D487/04 , C07D519/00 , C07D498/04
CPC classification number: C07D487/04 , C07D498/04 , C07D519/00
Abstract: The disclosure provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the disclosure are useful for treating immunological and oncological conditions.
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公开(公告)号：US09193723B2
公开(公告)日：2015-11-24
申请号：US13891349
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4985 , A61K45/06 , A61K31/5377 , C07D471/04 , C07D487/04 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K31/407
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
Abstract translation: 公开了抑制NAMPT活性的化合物，含有该化合物的组合物和治疗其中NAMPT表达的疾病的方法。
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公开(公告)号：US20170135994A9
公开(公告)日：2017-05-18
申请号：US14878858
申请日：2015-10-08
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4545 , A61K31/496
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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Patent Agency Ranking
公开(公告)号：US20160184282A1
公开(公告)日：2016-06-30
申请号：US14878858
申请日：2015-10-08
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4545 , A61K31/496
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号：US10266532B2
公开(公告)日：2019-04-23
申请号：US15829243
申请日：2017-12-01
Applicant: AbbVie Inc.
Inventor： Eric C. Breinlinger , Phil B. Cox , Justin D. Dietrich , Kristine E. Frank , Michael M. Friedman , Huan-Qui Li , Kenton L. Longenecker , Augustine T. Osuma , Ann Marie Rowley , Anil Vasudevan , Noel S. Wilson , Jerome Daanen , Stevan Djuric , Amanda W. Dombrowski , Arthur Gomtsyan , Robert Schmidt
IPC: C07D521/00 , C07D471/04 , C07D471/14 , C07D487/04 , C07D498/04 , C07D498/14 , C07D498/18 , C07D498/20 , C07D498/22 , C07D519/00 , C07D471/18 , C07D491/147 , C07D491/22
Abstract: The invention provides tricyclic heterocyclic compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the invention may be useful for treating immunological and oncological conditions.
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公开(公告)号：US20180179198A1
公开(公告)日：2018-06-28
申请号：US15829243
申请日：2017-12-01
Applicant: AbbVie Inc.
Inventor： Eric C. Breinlinger , Phil B. Cox , Justin D. Dietrich , Kristine E. Frank , Michael M. Friedman , Huan-Qui Li , Kenton L. Longenecker , Augustine T. Osuma , Ann Marie Rowley , Anil Vasudevan , Noel S. Wilson
IPC: C07D471/04 , C07D491/147 , C07D498/22 , C07D487/04 , C07D491/22 , C07D498/18 , C07D471/14 , C07D498/04 , C07D498/14 , C07D498/20 , C07D519/00 , C07D471/18
CPC classification number: C07D471/04 , C07D471/14 , C07D471/18 , C07D487/04 , C07D491/147 , C07D491/22 , C07D498/04 , C07D498/14 , C07D498/18 , C07D498/20 , C07D498/22 , C07D519/00
Abstract: The invention provides tricyclic heterocyclic compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the invention may be useful for treating immunological and oncological conditions.
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公开(公告)号：US20160184281A1
公开(公告)日：2016-06-30
申请号：US14878836
申请日：2015-10-08
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K31/5377 , A61K31/444
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号：US09187472B2
公开(公告)日：2015-11-17
申请号：US13891366
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , C07D487/04 , A61K31/437 , A61K31/4985 , A61K45/06 , A61K31/5377 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K31/407
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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