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公开(公告)号:US20170065575A1
公开(公告)日:2017-03-09
申请号:US15357383
申请日:2016-11-21
Applicant: AbbVie Inc.
Inventor: Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey
IPC: A61K31/4545 , A61K31/506 , A61K31/501 , A61K31/5377 , A61K31/496
CPC classification number: A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
Abstract translation: 公开了抑制NAMPT活性的化合物,含有该化合物的组合物和治疗其中NAMPT表达的疾病的方法。
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公开(公告)号:US20130303511A1
公开(公告)日:2013-11-14
申请号:US13891366
申请日:2013-05-10
Applicant: AbbVie Inc.
Inventor: Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , A61K45/06 , C07D487/04 , A61K31/4985 , A61K31/437 , A61K31/5377
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US20130303509A1
公开(公告)日:2013-11-14
申请号:US13891354
申请日:2013-05-10
Applicant: AbbVie Inc.
Inventor: Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey
IPC: C07D405/14 , C07D409/14 , A61K31/501 , C07D417/14 , A61K31/496 , A61K31/4545 , A61K31/5377
CPC classification number: A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US20130303508A1
公开(公告)日:2013-11-14
申请号:US13891349
申请日:2013-05-10
Applicant: AbbVie Inc.
Inventor: Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , A61K31/5377 , A61K45/06 , A61K31/496 , A61K31/55 , A61K31/4725 , A61K31/437 , A61K31/4545
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US20160168134A1
公开(公告)日:2016-06-16
申请号:US15048574
申请日:2016-02-19
Applicant: AbbVie Inc.
Inventor: Michael L. Curtin , Kenton Longenecker , Todd M. Hansen , Richard F. Clark , Bryan Sorensen , Howard R. Heyman , Zhiqin Ji
IPC: C07D405/14
CPC classification number: C07D405/14 , A61K45/06 , C07D401/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US09193723B2
公开(公告)日:2015-11-24
申请号:US13891349
申请日:2013-05-10
Applicant: AbbVie Inc.
Inventor: Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4985 , A61K45/06 , A61K31/5377 , C07D471/04 , C07D487/04 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K31/407
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
Abstract translation: 公开了抑制NAMPT活性的化合物,含有该化合物的组合物和治疗其中NAMPT表达的疾病的方法。
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公开(公告)号:US20160184281A1
公开(公告)日:2016-06-30
申请号:US14878836
申请日:2015-10-08
Applicant: AbbVie Inc.
Inventor: Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K31/5377 , A61K31/444
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US09296723B2
公开(公告)日:2016-03-29
申请号:US13891363
申请日:2013-05-10
Applicant: AbbVie Inc.
Inventor: Michael L. Curtin , Kenton Longenecker , Todd M. Hansen , Richard F. Clark , Bryan Sorensen , Howard R. Heyman , Zhiqin Ji
IPC: C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14 , A61K45/06
CPC classification number: C07D405/14 , A61K45/06 , C07D401/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US09187472B2
公开(公告)日:2015-11-17
申请号:US13891366
申请日:2013-05-10
Applicant: AbbVie Inc.
Inventor: Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , C07D487/04 , A61K31/437 , A61K31/4985 , A61K45/06 , A61K31/5377 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K31/407
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
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公开(公告)号:US20150141398A1
公开(公告)日:2015-05-21
申请号:US14603832
申请日:2015-01-23
Applicant: AbbVie Inc.
Inventor: Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey
IPC: A61K31/501 , A61K31/4545
CPC classification number: A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
Abstract translation: 公开了抑制NAMPT活性的化合物,含有该化合物的组合物和治疗其中NAMPT表达的疾病的方法。
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