-
公开(公告)号：US20190265212A1
公开(公告)日：2019-08-29
申请号：US16412704
申请日：2019-05-15
申请人： ACADEMIA SINICA
发明人： Chung-Hsuan CHEN , Chen-Yu HSIEH , Jung-Lee LIN
IPC分类号： G01N30/74
摘要： Apparatus and methods for high performance liquid chromatography. The apparatus includes a preparation loop comprising two linear stepping pumps, a sample loop comprising a sample injector, a chromatography column, and a detector device. The detector device can include a flash lamp, a flow cell, and a light sensor comprising an entrance slit, a grating; and a charge-coupled device array.
-
公开(公告)号：US20130206975A1
公开(公告)日：2013-08-15
申请号：US13691785
申请日：2012-12-01
申请人： Academia Sinica
发明人： Chung-Hsuan CHEN , Jung-Lee LIN , Nien-Yeen HSU , Yi-Sheng WANG
CPC分类号： H05H5/047 , H01J49/06 , H01J49/40 , H01J49/403
摘要： A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.
摘要翻译： 提供了一种用于加速分析物的新系统和方法，包括但不限于分子离子，生物分子，聚合物，纳米和微粒。 本发明可用于在诸如质谱法，进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。
-
公开(公告)号：US20200161110A1
公开(公告)日：2020-05-21
申请号：US16686203
申请日：2019-11-17
申请人： Academia Sinica
发明人： Abdil OZDEMIR , Jung-Lee LIN , Chung-Hsuan CHEN
摘要： Disclosed herein is a device for characterizing a biological sample or an airborne sample. According to embodiments of the present disclosure, the device comprises an electrospray source, a mass analyzer, a charge detector, and optionally, an ion guide. The present device is useful in analyzing the particle population in the biological or airborne sample based on the mass to charge (m/z) ratio and the charge (z) of each particle. Also disclosed herein are the methods of making a diagnosis of cancer by use of the present device, and methods of determining the mass distribution of particles in an airborne sample.
-
公开(公告)号：US20150160232A1
公开(公告)日：2015-06-11
申请号：US14298911
申请日：2014-06-07
申请人： Academia Sinica
CPC分类号： H01J49/0031 , G01N33/6818 , G01N33/6851 , H01J49/0054
摘要： Apparatus and methods for automatic amino acid sequencing of a glycopeptide by mass spectrometry. The glycopeptide is fragmented by higher energy collision dissociation fragmentation, and sequentially fragmented by collision induced dissociation fragmentation. The glycopeptide Y1 ion is isolated, and the mass spectra of fragmented glycopeptide Y1 ions provide mass spectral peaks corresponding to the amino acid sequence of the glycopeptide.
摘要翻译： 通过质谱法对糖肽进行自动氨基酸测序的装置和方法。 糖肽通过较高的能量碰撞解离断裂而碎裂，并通过碰撞诱导的解离片段依次碎裂。 分离糖肽Y1离子，碎片糖肽Y1离子的质谱提供对应于糖肽的氨基酸序列的质谱峰。
-
-
-
搜索结果
4 条记录 (耗时 0.011 秒)
