MOLECULAR ION ACCELERATOR
    1.
    发明申请
    MOLECULAR ION ACCELERATOR 有权
    分子加速器

    公开(公告)号:US20100276582A1

    公开(公告)日:2010-11-04

    申请号:US12431896

    申请日:2009-04-29

    摘要: A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.

    摘要翻译: 提供了一种用于加速分析物的新系统和方法,包括但不限于分子离子,生物分子,聚合物,纳米和微粒。 本发明可用于在诸如质谱法,进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。

    ORTHOGONAL ACCELERATION SYSTEM FOR TIME-OF-FLIGHT MASS SPECTROMETER

    公开(公告)号:US20160071717A1

    公开(公告)日:2016-03-10

    申请号:US14928793

    申请日:2015-10-30

    发明人: David G. Welkie

    IPC分类号: H01J49/40 H01J49/00

    摘要: An orthogonal pulse accelerator for a Time-of-Flight mass analyzer includes an electrically-conductive first plate extending in a first plane, and a second plate spaced from the first plate. The second plate includes a grid that defines a plurality of apertures each having a first dimension extending in a first direction and a second dimension orthogonal to the first dimension, the first and second dimensions lying in the second plane and the second dimension begin larger than the first dimension. The first and second plates are positioned in the Time-of-Flight mass analyzer to receive, during operation of the mass analyzer, an ion beam propagating in the first direction in a region between the first and second plates, and the orthogonal pulse accelerator directs ions in the ion beam through the apertures.

    Orthogonal acceleration system for time-of-flight mass spectrometer

    公开(公告)号:US09177777B2

    公开(公告)日:2015-11-03

    申请号:US14610003

    申请日:2015-01-30

    发明人: David G. Welkie

    IPC分类号: H01J49/40 H01J49/00

    摘要: An orthogonal pulse accelerator for a Time-of-Flight mass analyzer includes an electrically-conductive first plate extending in a first plane, and a second plate spaced from the first plate. The second plate includes a grid that defines a plurality of apertures each having a first dimension extending in a first direction and a second dimension orthogonal to the first dimension, the first and second dimensions lying in the second plane and the second dimension begin larger than the first dimension. The first and second plates are positioned in the Time-of-Flight mass analyzer to receive, during operation of the mass analyzer, an ion beam propagating in the first direction in a region between the first and second plates, and the orthogonal pulse accelerator directs ions in the ion beam through the apertures.

    Orthogonal acceleration system for time-of-flight mass spectrometer
    4.
    发明授权
    Orthogonal acceleration system for time-of-flight mass spectrometer 有权
    飞行时间质谱仪的正交加速系统

    公开(公告)号:US09576782B2

    公开(公告)日:2017-02-21

    申请号:US14928793

    申请日:2015-10-30

    发明人: David G. Welkie

    摘要: An orthogonal pulse accelerator for a Time-of-Flight mass analyzer includes an electrically-conductive first plate extending in a first plane, and a second plate spaced from the first plate. The second plate includes a grid that defines a plurality of apertures each having a first dimension extending in a first direction and a second dimension orthogonal to the first dimension, the first and second dimensions lying in the second plane and the second dimension begin larger than the first dimension. The first and second plates are positioned in the Time-of-Flight mass analyzer to receive, during operation of the mass analyzer, an ion beam propagating in the first direction in a region between the first and second plates, and the orthogonal pulse accelerator directs ions in the ion beam through the apertures.

    摘要翻译: 用于飞行时间质量分析器的正交脉冲加速器包括在第一平面中延伸的导电第一板和与第一板间隔开的第二板。 第二板包括限定多个孔的栅格,每个孔具有在第一方向上延伸的第一尺寸和与第一尺寸正交的第二尺寸,第一和第二尺寸位于第二平面中,而第二尺寸开始大于 第一维度。 第一和第二板位于飞行时间质量分析器中,以在质量分析仪的操作期间接收在第一和第二板之间的区域中沿第一方向传播的离子束,并且正交脉冲加速器指示 离子束中的离子通过孔。

    Molecular ion accelerator
    5.
    发明授权
    Molecular ion accelerator 有权
    分子离子加速器

    公开(公告)号:US08344317B2

    公开(公告)日:2013-01-01

    申请号:US13365105

    申请日:2012-02-02

    IPC分类号: H01J49/26 H01J49/40

    摘要: A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.

    摘要翻译: 提供了一种用于加速分析物的新系统和方法,包括但不限于分子离子,生物分子,聚合物,纳米和微粒。 本发明可用于在诸如质谱法,进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。

    SHORT PULSE NEUTRON GENERATOR
    7.
    发明申请
    SHORT PULSE NEUTRON GENERATOR 审中-公开
    短脉冲中子发生器

    公开(公告)号:US20160302297A1

    公开(公告)日:2016-10-13

    申请号:US15190035

    申请日:2016-06-22

    IPC分类号: H05H3/06 H05H5/04 H05H5/03

    摘要: Short pulse neutron generators are described herein. In a general embodiment, the short pulse neutron generator includes a Blumlein structure. The Blumlein structure includes a first conductive plate, a second conductive plate, a third conductive plate, at least one of an inductor or a resistor, a switch, and a dielectric material. The first conductive plate is positioned relative to the second conductive plate such that a gap separates these plates. A vacuum chamber is positioned in the gap, and an ion source is positioned to emit ions in the vacuum chamber. The third conductive plate is electrically grounded, and the switch is operable to electrically connect and disconnect the second conductive plate and the third conductive plate. The at least one of the resistor or the inductor is coupled to the first conductive plate and the second conductive plate.

    摘要翻译: 本文描述了短脉冲中子发生器。 在一般实施例中,短脉冲中子发生器包括Blumlein结构。 Blumlein结构包括第一导电板,第二导电板,第三导电板,电感器或电阻器中的至少一个,开关和电介质材料。 第一导电板相对于第二导电板定位,使得间隙分离这些板。 真空室位于间隙中,离子源被定位成在真空室中发射离子。 第三导电板电接地,并且开关可操作以电连接和断开第二导电板和第三导电板。 电阻器或电感器中的至少一个耦合到第一导电板和第二导电板。

    ORTHOGONAL ACCELERATION SYSTEM FOR TIME-OF-FLIGHT MASS SPECTROMETER
    8.
    发明申请
    ORTHOGONAL ACCELERATION SYSTEM FOR TIME-OF-FLIGHT MASS SPECTROMETER 有权
    用于飞行时间质谱仪的正交加速系统

    公开(公告)号:US20150155153A1

    公开(公告)日:2015-06-04

    申请号:US14610003

    申请日:2015-01-30

    发明人: David G. Welkie

    IPC分类号: H01J49/40

    摘要: An orthogonal pulse accelerator for a Time-of-Flight mass analyzer includes an electrically-conductive first plate extending in a first plane, and a second plate spaced from the first plate. The second plate includes a grid that defines a plurality of apertures each having a first dimension extending in a first direction and a second dimension orthogonal to the first dimension, the first and second dimensions lying in the second plane and the second dimension begin larger than the first dimension. The first and second plates are positioned in the Time-of-Flight mass analyzer to receive, during operation of the mass analyzer, an ion beam propagating in the first direction in a region between the first and second plates, and the orthogonal pulse accelerator directs ions in the ion beam through the apertures.

    摘要翻译: 用于飞行时间质量分析器的正交脉冲加速器包括在第一平面中延伸的导电第一板和与第一板间隔开的第二板。 第二板包括限定多个孔的栅格,每个孔具有在第一方向上延伸的第一尺寸和与第一尺寸正交的第二尺寸,第一和第二尺寸位于第二平面中,而第二尺寸开始大于 第一维度。 第一和第二板位于飞行时间质量分析器中,以在质量分析仪的操作期间接收在第一和第二板之间的区域中沿第一方向传播的离子束,并且正交脉冲加速器指示 离子束中的离子通过孔。

    MOLECULAR ION ACCELERATOR
    9.
    发明申请
    MOLECULAR ION ACCELERATOR 有权
    分子加速器

    公开(公告)号:US20130206975A1

    公开(公告)日:2013-08-15

    申请号:US13691785

    申请日:2012-12-01

    申请人: Academia Sinica

    IPC分类号: H05H5/04 H01J49/40

    摘要: A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.

    摘要翻译: 提供了一种用于加速分析物的新系统和方法,包括但不限于分子离子,生物分子,聚合物,纳米和微粒。 本发明可用于在诸如质谱法,进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。

    MOLECULAR ION ACCELERATOR
    10.
    发明申请
    MOLECULAR ION ACCELERATOR 有权
    分子加速器

    公开(公告)号:US20120126112A1

    公开(公告)日:2012-05-24

    申请号:US13365105

    申请日:2012-02-02

    IPC分类号: H01J49/40 H05H9/00 H01J49/10

    摘要: A novel system and methods for accelerating analytes including, without limitation, molecular ions, biomolecules, polymers, nano- and microparticles, is provided. The invention can be useful for increasing detection sensitivity in applications such as mass spectrometry, performing collision-induced dissociation molecular structure analysis, and probing surfaces and samples using accelerated analyte.

    摘要翻译: 提供了一种用于加速分析物的新系统和方法,包括但不限于分子离子,生物分子,聚合物,纳米和微粒。 本发明可用于在诸如质谱法,进行碰撞诱导的解离分子结构分析和使用加速分析物的探测表面和样品等应用中提高检测灵敏度。