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1.发明申请公开(公告)号：US20170296387A1
公开(公告)日：2017-10-19
申请号：US15583053
申请日：2017-05-01
申请人： Acclarent, Inc.
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
IPC分类号： A61F11/00
CPC分类号： A61F11/002
摘要： Methods and devices for providing a gas pathway between the nasopharynx and the Eustachian tube are provided. One device may include a lumen with a valve. A portion of the valve may be tethered to adjacent muscle. Another portion of the valve may be tethered to adjacent cartilage. When the muscle contracts the valve may open through movement of the tethers, and provide a gas pathway between the nasopharynx and the Eustachian tube.
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公开(公告)号：US09629656B2
公开(公告)日：2017-04-25
申请号：US14845604
申请日：2015-09-04
申请人： Acclarent, Inc.
IPC分类号： A61B17/34 , A61B1/313 , A61B6/12 , A61B6/00 , A61B90/94 , A61B90/00 , A61B17/00 , A61B90/50 , A61B34/20
CPC分类号： A61B17/3415 , A61B1/313 , A61B6/12 , A61B6/485 , A61B90/39 , A61B90/50 , A61B90/94 , A61B2017/00292 , A61B2017/3407 , A61B2017/3486 , A61B2034/2051 , A61B2090/3958 , A61B2090/397 , A61B2090/3975 , A61B2090/3983
摘要： Devices and methods wherein an adapter is used to attach an electromagnetic image guidance component to a medical device such that an electromagnetic image guidance system may be used to track the location of the medical device within the body of a human or animal subject.
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公开(公告)号：US20160287145A1
公开(公告)日：2016-10-06
申请号：US14827568
申请日：2015-08-17
申请人： Acclarent, Inc.
发明人： Joshua Makower
摘要： A method for detecting characteristics of a Eustachian tube of a patient includes communicating pressurized air into an oro-nasal cavity of the patient. The method further includes directing an energy signal into the oro-nasal cavity. The method further includes detecting transmission of the energy signal from the oro-nasal cavity through the Eustachian tube with a sensor. The method further includes determining at least one characteristic of the Eustachian tube based on whether the energy signal is detected by the sensor.
摘要翻译： 用于检测患者的咽鼓管的特征的方法包括将加压空气连通到患者的鼻腔中。 该方法还包括将能量信号引导到鼻腔中。 该方法还包括通过传感器检测来自鼻腔的能量信号通过咽鼓管的传播。 该方法还包括基于传感器检测到能量信号来确定咽鼓管的至少一个特征。
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公开(公告)号：US09370649B2
公开(公告)日：2016-06-21
申请号：US14614799
申请日：2015-02-05
申请人： Acclarent, Inc.
发明人： John Y. Chang , Joshua Makower , Julia D. Vrany , John H. Morriss , Ketan P. Muni , Isaac J. Kim , Hung V. Ha , William M. Facteau , Amrish Jayprakash Walke
IPC分类号： A61M29/00 , A61B17/24 , A61B17/3207 , A61M29/02 , A61B1/233 , A61B17/12 , A61B17/16 , A61B17/32 , A61M25/09 , A61M25/06 , A61B19/00 , A61M25/00 , A61M25/10 , A61B17/00
CPC分类号： A61M29/00 , A61B1/233 , A61B17/12104 , A61B17/12136 , A61B17/1657 , A61B17/1688 , A61B17/24 , A61B17/320016 , A61B17/320725 , A61B34/20 , A61B2017/00292 , A61B2017/246 , A61B2034/2051 , A61B2090/3764 , A61B2503/40 , A61M25/0041 , A61M25/0054 , A61M25/0662 , A61M25/09 , A61M25/1002 , A61M29/02 , A61M2025/0008 , A61M2025/1079 , A61M2029/025 , A61M2210/0618 , A61M2210/1028
摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.
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5.发明授权公开(公告)号：US09308361B2
公开(公告)日：2016-04-12
申请号：US13784293
申请日：2013-03-04
申请人： Acclarent, Inc.
发明人： Ketan P. Muni , Hung V. Ha , John H. Morriss , William E. Bolger , Joshua Makower , John Y. Chang , Randy S. Chan , Nga K. Van , Anton G. Clifford , William M. Facteau
IPC分类号： A61M29/02 , A61B17/24 , A61B17/34 , A61F11/00 , A61M25/10 , A61M25/00 , A61M25/04 , A61B17/12
CPC分类号： A61M29/02 , A61B17/1204 , A61B17/12104 , A61B17/12136 , A61B17/24 , A61B17/3417 , A61B17/3421 , A61B17/3478 , A61F11/004 , A61M25/0075 , A61M25/0084 , A61M25/04 , A61M25/10 , A61M2025/105 , A61M2025/1052 , A61M2025/1086 , A61M2210/0618
摘要： A method for treating ethmoid disease in human or non-human animal subjects includes inserting a sheath containing an implantable device having an expandable member. The sheath is removed from the implantable device causing the expandable member to expand, allowing for stability of the implantable device in the subject. Stenting, spacing, draining, ventilating and/or delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects may also be involved.
摘要翻译： 用于在人或非人类动物受试者中治疗筛骨病的方法包括插入含有具有可扩张构件的可植入装置的护套。 护套从可植入装置移除，导致可扩张构件膨胀，从而允许可植入装置在受试者中的稳定性。 还可能涉及支架，间隔，排水，通气和/或递送药物和其他治疗或诊断物质到人类或非人类动物受试者体内所需位置。
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公开(公告)号：US09220879B2
公开(公告)日：2015-12-29
申请号：US14266025
申请日：2014-04-30
申请人： Acclarent, Inc.
发明人： John Y. Chang , Joshua Makower , Julia D. Vrany , John H. Morriss , Ketan P. Muni , Isaac J. Kim , Hung V. Ha , William M. Facteau
CPC分类号： A61M29/00 , A61B1/233 , A61B17/12104 , A61B17/12136 , A61B17/1657 , A61B17/1688 , A61B17/24 , A61B17/320016 , A61B17/320725 , A61B34/20 , A61B2017/00292 , A61B2017/246 , A61B2034/2051 , A61B2090/3764 , A61B2503/40 , A61M25/0041 , A61M25/0054 , A61M25/0662 , A61M25/09 , A61M25/1002 , A61M29/02 , A61M2025/0008 , A61M2025/1079 , A61M2029/025 , A61M2210/0618 , A61M2210/1028
摘要： Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.
摘要翻译： 使用具有柔性或刚性器械的微创方法诊断和/或治疗鼻窦炎和其他耳朵，鼻子和喉咙疾病。 各种方法和装置用于重建或改变耳朵，鼻子或喉咙中的窦口或导管或其他解剖结构的形状，尺寸或构型; 植入装置，细胞或组织; 从耳朵，鼻子或喉咙去除物质; 提供诊断或治疗物质或执行其他诊断或治疗程序。 可以使用引入装置（例如，引导导管，管，导线，细长探针，其它细长构件）来促进工作装置（例如，导管例如球囊导管，导线，组织切割或重塑装置，用于植入元件如支架的装置， 电外科装置，能量发射装置，用于递送诊断或治疗剂，物质输送植入物，范围等的装置）到耳鼻窦或耳朵，鼻子或喉咙中的其他结构中。 提供特定装置（例如，管状引导件，导丝，气囊导管，管状护套），制造和使用这种装置来治疗耳朵，鼻子或喉咙的障碍的方法。
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公开(公告)号：US20150328051A1
公开(公告)日：2015-11-19
申请号：US14722337
申请日：2015-05-27
申请人： Acclarent, Inc.
发明人： John H. Morriss , Greg Liu , Rohit Girotra , Tom Thanh Vo , Richard Roy Newhauser, JR. , Thomas R. Jenkins , Joshua Makower
CPC分类号： A61F11/002 , A61F11/006 , A61M1/0031 , A61M1/008 , A61M3/0262 , A61M3/0279 , A61M2210/0675
摘要： A method is disclosed for clearing effusion from an ear. The method may include applying liquid to an ear canal, which is proximal to a perforated tympanic membrane, which is proximal to a middle ear containing effusion, applying an ear device to seal and pressurize the liquid inside the ear canal, the ear device regulating the amount of pressure inside the ear canal, and inducing a Eustachian tube, which is distal to the middle ear, to open, which causes the fluid to displace the effusion into the Eustachian tube.
摘要翻译： 公开了一种从耳朵清除渗出物的方法。 该方法可以包括将液体施加到耳道，所述耳道接近穿孔鼓膜，所述鼓膜接近含有渗出液的中耳，施加耳朵装置以密封和加压耳道内的液体，耳朵装置调节 耳道内的压力量，以及诱导位于中耳远端的咽鼓管打开，导致流体将渗出液置于咽鼓管内。
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8.发明申请IMPLANTABLE DEVICES AND METHODS FOR DELIVERING DRUGS AND OTHER SUBSTANCES TO TREAT SINUSITIS AND OTHER DISORDERS 审中-公开用于输送药物和其他物质以治疗神经痛和其他疾病的可植入装置和方法公开(公告)号：US20150217097A1
公开(公告)日：2015-08-06
申请号：US14689245
申请日：2015-04-17
申请人： Acclarent, Inc.
CPC分类号： A61M31/002 , A61B5/06 , A61B5/064 , A61B5/411 , A61B17/24 , A61B17/320725 , A61B17/320758 , A61B17/320783 , A61B17/3478 , A61B34/20 , A61B2017/22061 , A61F2/18 , A61F2/82 , A61F2002/825 , A61F2250/0039 , A61M25/0029 , A61M25/007 , A61M25/10 , A61M2025/0037 , A61M2025/105 , A61M2025/1052
摘要： Implantable devices and methods for delivering drugs and other substances to locations within the body of a human or animal subject to treat or diagnose sinusitis and a variety of other disorders. The invention includes implantable substance delivery devices that comprise reservoirs and barriers that control the rate at which substances pass out of the reservoirs. The delivery devices may be advanced into the body using guidewires, catheters, ports, introducers and other access apparatus. In some embodiments the delivery devices may be loaded with one or more desired substance before their introduction into the body. In other embodiments the delivery devices are loaded and/or reloaded with a desired substance after the delivery device has been introduced into the body.
摘要翻译： 用于将药物和其他物质递送到人或动物身体内的位置以进行治疗或诊断鼻窦炎和各种其他疾病的可植入装置和方法。 本发明包括可植入物质输送装置，其包括控制物质从储存器中流出的速率的储存器和屏障。 输送装置可以使用导线，导管，端口，引导器和其它存取装置进入体内。 在一些实施方案中，递送装置可以在引入体内之前装载一种或多种所需物质。 在其他实施方案中，递送装置在输送装置已经被引入体内之后被装载和/或重新加载所需物质。
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9.发明申请公开(公告)号：US20130090544A1
公开(公告)日：2013-04-11
申请号：US13647562
申请日：2012-10-09
申请人： ACCLARENT, INC.
发明人： Anton G. Clifford , Greg Liu , John H. Morriss , Joshua Makower , William M. Facteau , Eric Goldfarb , John Y. Chang
CPC分类号： A61M31/00 , A61B5/0077 , A61B2017/00787 , A61F11/002 , A61F2230/0039 , A61F2230/0052 , A61F2250/0039 , A61M2210/0662 , A61N1/30 , A61N1/306
摘要： Systems and methods for treating a patient having a head with a first ear and a second car, function by mounting a support structure to the head of the patient; aligning the support structure with a target tissue in an ear canal of the first ear; stabilizing the support structure relative to the target tissue by injecting a material into the canal and hardening the material; and actuating a device while the device is supported by the support system so that the device therapeutically remodels the target tissue of the first ear.
摘要翻译： 用于治疗患有具有第一耳朵和第二部分的头部的患者的系统和方法通过将支撑结构安装到患者的头部而起作用; 将支撑结构与第一耳的耳道中的目标组织对准; 通过将材料注入到管道中并使材料硬化来相对于目标组织稳定支撑结构; 以及当所述装置由所述支撑系统支撑时启动装置，使得所述装置治疗性地改造所述第一耳朵的目标组织。
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公开(公告)号：US11065061B2
公开(公告)日：2021-07-20
申请号：US15083826
申请日：2016-03-29
申请人： Acclarent, Inc.
发明人： Joshua Makower
IPC分类号： A61B5/00 , A61B5/06 , A61B6/00 , A61B34/20 , A61B90/16 , A61B90/00 , A61B50/13 , A61B6/03 , A61M29/02 , A61B1/233 , A61M25/09 , A61B17/00 , A61B18/20 , A61B18/02 , A61B34/10
摘要： Devices, systems and methods for performing image guided interventional and surgical procedures, including various procedures to treat sinusitis and other disorders of the paranasal sinuses, ears, nose or throat.
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